Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Immunomodulator |
Is a |
False |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Immunosuppressant (substance) |
Is a |
False |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Immune enhancement agent (substance) |
Is a |
False |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Immunologic agent |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Intraperitoneal immunotherapy (procedure) |
Direct substance |
False |
Immunologic agent (substance) |
Inferred relationship |
Some |
1 |
Abciximab (substance) |
Is a |
False |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Ciclosporin |
Is a |
False |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Immunotherapeutic agent |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Subcutaneous immunotherapy |
Direct substance |
False |
Immunologic agent (substance) |
Inferred relationship |
Some |
1 |
Vaccine, immunoglobulin, AND/OR antiserum |
Is a |
False |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Intravenous immunotherapy |
Direct substance |
False |
Immunologic agent (substance) |
Inferred relationship |
Some |
1 |
Intraperitoneal immunotherapy (procedure) |
Direct substance |
False |
Immunologic agent (substance) |
Inferred relationship |
Some |
1 |
Subcutaneous immunotherapy |
Direct substance |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
1 |
Intravenous immunotherapy |
Direct substance |
False |
Immunologic agent (substance) |
Inferred relationship |
Some |
1 |
Intravenous immunotherapy |
Direct substance |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
1 |
Intraperitoneal immunotherapy (procedure) |
Direct substance |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
1 |
Uramustine |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Teniposide (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Ocrelizumab |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Pomalidomide |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Semustine |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Dimethyl fumarate (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Thymalfasin |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Nitrogen mustard derivative (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Pyrimidine analog (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Nitrosurea (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Imiquimod (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Etoposide phosphate (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Canakinumab (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Triazene antineoplastic (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Bortezomib (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Belimumab (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Antifolate (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Purine antagonist |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Oprelvekin |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Adalimumab (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Etanercept (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Triethylenemelamine (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Mitoxantrone (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Inosine pranobex (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Etoposide (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Leflunomide (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Paclitaxel (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Sarilumab (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Ixazomib (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Mifamurtide |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Purine analog (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Anakinra (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Pipobroman |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Substance with interleukin 5 receptor antagonist mechanism of action (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Docetaxel (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Rilonacept (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Mitobronitol |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Carfilzomib |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Brodalumab (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Vinorelbine (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Lenalidomide (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Albumin bound paclitaxel (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Pixantrone (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Human mesenchymal stem cell (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Teriflunomide (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Busulfan (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Treosulfan (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Thiotepa (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Substance with interleukin 23 receptor antagonist mechanism of action (substance) |
Is a |
False |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Mitoxantrone hydrochloride (substance) |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Ixazomib citrate |
Is a |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
|
Antineoplastic chemoimmunotherapy (regime/therapy) |
Direct substance |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
2 |
Chimeric antigen receptor T-cell immunotherapy (procedure) |
Direct substance |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
1 |
Injection of immunotherapeutic agent (procedure) |
Direct substance |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
1 |
Tumor infiltrating lymphocyte therapy (procedure) |
Direct substance |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
1 |
A rare, acquired pituitary hormone deficiency characterised by inflammation of the pituitary gland secondary to immunotherapy for cancer treatments (such as monoclonal antibodies against cytotoxic T lymphocytes antigen, programmed cell death protein-1, and programmed cell death ligand molecules). Major clinical features include headache, fatigue, adrenal insufficiency and hypothyroidism. Patients may also have nausea and vomiting associated to the headache as well as dizziness and hot flashes. Enlargement of the pituitary gland is present in the brain imaging. |
Causative agent (attribute) |
True |
Immunologic agent (substance) |
Inferred relationship |
Some |
1 |