386835005: Mercaptopurine (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Immunomodulator\Antimetabolite (substance)\Purine analog (substance)\Mercaptopurine (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Immunologic agent (substance)\Purine analog (substance)\Mercaptopurine (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Antimetabolite (substance)\Purine analog (substance)\Mercaptopurine (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Purine and/or purine derivative\Purine analog (substance)\Mercaptopurine (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound\Purine and/or purine derivative\Purine analog (substance)\Mercaptopurine (substance)
\Organic compound\Organic nitrogen compound\Purine and/or purine derivative\Purine analog (substance)\Mercaptopurine (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

1461013018 Mercaptopurine (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

1480950017 Mercaptopurine en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

5382313016 Mercaptopurine monohydrate en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

5382314010 6-mercaptopurine monohydrate en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Mercaptopurine (substance)	Is a	Purine antagonist	false	Inferred relationship	Some
Mercaptopurine (substance)	Is a	Purine analog (substance)	true	Inferred relationship	Some
Mercaptopurine (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	A substance that competes with, replaces or inhibits a specific metabolite of a cell and thereby interferes with the cell's normal metabolic functioning.	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing mercaptopurine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Mercaptopurine measurement	Component	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Accidental mercaptopurine poisoning	Causative agent (attribute)	False	Mercaptopurine (substance)	Inferred relationship	Some
Intentional mercaptopurine poisoning	Causative agent (attribute)	False	Mercaptopurine (substance)	Inferred relationship	Some
Mercaptopurine poisoning of undetermined intent	Causative agent (attribute)	False	Mercaptopurine (substance)	Inferred relationship	Some	1
Mercaptopurine adverse reaction	Causative agent (attribute)	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Allergy to mercaptopurine (finding)	Causative agent (attribute)	False	Mercaptopurine (substance)	Inferred relationship	Some
Mercaptopurine overdose	Causative agent (attribute)	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Accidental mercaptopurine overdose	Causative agent (attribute)	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Intentional mercaptopurine overdose	Causative agent (attribute)	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Mercaptopurine overdose of undetermined intent	Causative agent (attribute)	False	Mercaptopurine (substance)	Inferred relationship	Some	1
Mercaptopurine 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Mercaptopurine (substance)	Inferred relationship	Some
Poisoning by mercaptopurine	Causative agent (attribute)	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Accidental mercaptopurine poisoning	Causative agent (attribute)	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Intentional mercaptopurine poisoning	Causative agent (attribute)	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Quantitative measurement of mercaptopurine	Component	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Allergy to mercaptopurine (finding)	Causative agent (attribute)	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Product containing mercaptopurine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Mercaptopurine therapy (procedure)	Direct substance	True	Mercaptopurine (substance)	Inferred relationship	Some	2
Mercaptopurine 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Mercaptopurine (substance)	Inferred relationship	Some	1
Mercaptopurine 50 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Mercaptopurine 50 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Mercaptopurine only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Product containing only mercaptopurine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Product containing precisely mercaptopurine 20 milligram/1 milliliter conventional release oral suspension (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Mercaptopurine (substance)	Inferred relationship	Some	1
Product containing precisely mercaptopurine 20 milligram/1 milliliter conventional release oral suspension (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Mercaptopurine (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461013018	Mercaptopurine (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1480950017	Mercaptopurine	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
5382313016	Mercaptopurine monohydrate	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
5382314010	6-mercaptopurine monohydrate	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core