Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Product containing folinic acid (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid adverse reaction |
Causative agent (attribute) |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |
Allergy to folinic acid |
Causative agent (attribute) |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 10mg/mL injection solution 5mL ampule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 10mg/mL injection solution 10mL vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 10mg/mL injection solution 2.5mL ampule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 10mg/mL injection solution 17.5mL vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 10mg/mL injection solution 35mL vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 7.5mg/mL injection solution 2mL ampule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 10mg/mL injection solution 30mL vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 15 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 3mg/mL injection solution 1mL ampule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 15mg powder for injection solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 30mg powder for injection solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 3mg/mL injection solution 10mL ampule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 15mg injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Product containing precisely calcium folinate 15 milligram/1 each conventional release oral tablet (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 50mg/mL injection solution 2mL vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 50mg/mL injection solution 8mL vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 50mg/mL injection solution 18mL vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Levofolinic acid (substance) |
Is a |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid preparation |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Product containing calcium leucovorin |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Leucovorin Calcium 350mg powder for injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Leucovorin Calcium 200mg powder for injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Leucovorin Calcium 50mg powder for injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Leucovorin Calcium 100mg powder for injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Leucovorin Calcium 500mg powder for injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Levofolinic acid 50mg/5mL injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 15mg injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Product containing precisely calcium folinate 5 milligram/1 each conventional release oral tablet (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 100mg/2mL injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 400mg/8mL injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Folinic acid 900mg/18mL injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Product containing folinic acid (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |
Allergy to folinic acid |
Causative agent (attribute) |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |
Folinic acid 15 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |
Folinic acid 15 mg oral tablet |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |
Folinic acid 15 mg oral tablet |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |
Folinic acid-containing product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |
Sodium folinate (substance) |
This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged. |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Product containing only folinic acid (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |
Folinic acid only product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |
Calcium folinate |
This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged. |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
|
Product containing only folinic acid in parenteral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |
FOLFIRI antineoplastic chemotherapy regimen |
Direct substance |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
3 |
FOLFIRINOX antineoplastic chemotherapy regimen |
Direct substance |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
4 |
Folinic acid-containing product in parenteral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |
Product containing precisely folinic acid (as calcium folinate) 10 milligram/1 milliliter conventional release solution for injection (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |
Product containing precisely folinic acid (as calcium folinate) 7.5 milligram/1 milliliter conventional release solution for injection (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |
Product containing precisely folinic acid (as calcium folinate) 15 milligram/1 milliliter conventional release solution for injection (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |
Product containing precisely folinic acid (as calcium folinate) 3 milligram/1 milliliter conventional release solution for injection (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Folinic acid (substance) |
Inferred relationship |
Some |
1 |