109983007: Monoclonal gammopathy (disorder)

SNOMED CT Concept\Clinical finding (finding)\...

\Procedure related finding\Evaluation finding\Measurement finding\...

\Finding of substance level (finding)\Finding of blood substance level\Blood substance level above reference range\Gammopathy (disorder)\Disorder of increased production of immunoglobulin protein (disorder)\Monoclonal gammopathy (clinical)
\Finding of substance level (finding)\Finding of blood substance level\Finding of protein in serum or plasma\Gammopathy (disorder)\Disorder of increased production of immunoglobulin protein (disorder)\Monoclonal gammopathy (clinical)
\Finding of substance level (finding)\Protein level - finding\Finding of paraprotein measurement (finding)\Paraprotein detected (finding)\Monoclonal gammopathy (clinical)
\Finding of substance level (finding)\Protein level - finding\Finding of protein in serum or plasma\Gammopathy (disorder)\Disorder of increased production of immunoglobulin protein (disorder)\Monoclonal gammopathy (clinical)
\Finding of substance level (finding)\Protein level - finding\Globulin level - finding\Globulin level outside reference range (finding)\Globulin above reference range\Gammopathy (disorder)\Disorder of increased production of immunoglobulin protein (disorder)\Monoclonal gammopathy (clinical)
\Finding of substance level (finding)\Protein level - finding\Immunoglobulin level - finding\Immunoglobulins outside reference range\Immunoglobulin above reference range (finding)\Disorder of increased production of immunoglobulin protein (disorder)\Monoclonal gammopathy (clinical)

\Measurement finding outside reference range\Measurement finding above reference range\Blood substance level above reference range\Gammopathy (disorder)\Disorder of increased production of immunoglobulin protein (disorder)\Monoclonal gammopathy (clinical)
\Measurement finding outside reference range\Measurement finding above reference range\Immunoglobulin above reference range (finding)\Disorder of increased production of immunoglobulin protein (disorder)\Monoclonal gammopathy (clinical)
\Measurement finding outside reference range\Measurement finding above reference range\Globulin above reference range\Gammopathy (disorder)\Disorder of increased production of immunoglobulin protein (disorder)\Monoclonal gammopathy (clinical)
\Measurement finding outside reference range\Immunoglobulins outside reference range\Immunoglobulin above reference range (finding)\Disorder of increased production of immunoglobulin protein (disorder)\Monoclonal gammopathy (clinical)
\Measurement finding outside reference range\Globulin level outside reference range (finding)\Globulin above reference range\Gammopathy (disorder)\Disorder of increased production of immunoglobulin protein (disorder)\Monoclonal gammopathy (clinical)

\Detected by measurement (finding)\Paraprotein detected (finding)\Monoclonal gammopathy (clinical)

\Disease\Disorder of immune function (disorder)\Gammopathy (disorder)\Disorder of increased production of immunoglobulin protein (disorder)\Monoclonal gammopathy (clinical)

Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2005. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Monoclonal gammopathy (clinical)	Is a	Clonal protein disease	false	Inferred relationship	Some
Monoclonal gammopathy (clinical)	Finding site	Hematopoietic system structure	false	Inferred relationship	Some
Monoclonal gammopathy (clinical)	Finding site	Leukocyte	false	Inferred relationship	Some
Monoclonal gammopathy (clinical)	Finding site	Structure of immune system (body structure)	false	Inferred relationship	Some	1
Monoclonal gammopathy (clinical)	Associated morphology	Monoclonal gammopathy of undetermined significance	false	Inferred relationship	Some	1
Monoclonal gammopathy (clinical)	Is a	Neoplastic disease of uncertain behavior	false	Inferred relationship	Some
Monoclonal gammopathy (clinical)	Is a	Disorder of increased production of immunoglobulin protein (disorder)	true	Inferred relationship	Some
Monoclonal gammopathy (clinical)	Has definitional manifestation	Serum gamma globulin above reference range	false	Inferred relationship	Some
Monoclonal gammopathy (clinical)	Has definitional manifestation	Paraprotein detected (finding)	false	Inferred relationship	Some
Monoclonal gammopathy (clinical)	Has definitional manifestation	Immune system finding	false	Inferred relationship	Some
Monoclonal gammopathy (clinical)	Has definitional manifestation	Immunoglobulin above reference range (finding)	false	Inferred relationship	Some
Monoclonal gammopathy (clinical)	Has interpretation	Above reference range	true	Inferred relationship	Some	1
Monoclonal gammopathy (clinical)	Interprets	Serum globulin measurement	true	Inferred relationship	Some	1
Monoclonal gammopathy (clinical)	Interprets	Paraprotein measurement	true	Inferred relationship	Some	3
Monoclonal gammopathy (clinical)	Is a	Paraprotein detected (finding)	true	Inferred relationship	Some
Monoclonal gammopathy (clinical)	Has interpretation	Above reference range	true	Inferred relationship	Some	2
Monoclonal gammopathy (clinical)	Interprets	Immunoglobulin measurement (procedure)	true	Inferred relationship	Some	2
Monoclonal gammopathy (clinical)	Has interpretation	Present (qualifier value)	false	Inferred relationship	Some	3
Monoclonal gammopathy (clinical)	Pathological process (attribute)	Abnormal immune process (qualifier value)	true	Inferred relationship	Some	4
Monoclonal gammopathy (clinical)	Has interpretation	Detected	true	Inferred relationship	Some	3

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Monoclonal gammopathy of undetermined significance (MGUS)	Is a	False	Monoclonal gammopathy (clinical)	Inferred relationship	Some
Secondary monoclonal gammopathy	Is a	False	Monoclonal gammopathy (clinical)	Inferred relationship	Some
Benign monoclonal gammopathy	Is a	True	Monoclonal gammopathy (clinical)	Inferred relationship	Some
POEMS syndrome	Is a	True	Monoclonal gammopathy (clinical)	Inferred relationship	Some
Monoclonal gammopathy of uncertain significance	Is a	True	Monoclonal gammopathy (clinical)	Inferred relationship	Some
Triclonal gammopathy	Is a	True	Monoclonal gammopathy (clinical)	Inferred relationship	Some
Waldenström macroglobulinaemia	Is a	True	Monoclonal gammopathy (clinical)	Inferred relationship	Some
Light chain disease	Is a	True	Monoclonal gammopathy (clinical)	Inferred relationship	Some
Biclonal gammopathy	Is a	True	Monoclonal gammopathy (clinical)	Inferred relationship	Some
Mixed cryoimmunoglobulinemia with monoclonal component	Is a	True	Monoclonal gammopathy (clinical)	Inferred relationship	Some
Heavy chain disease	Is a	True	Monoclonal gammopathy (clinical)	Inferred relationship	Some
Other paraproteinemias	Is a	False	Monoclonal gammopathy (clinical)	Inferred relationship	Some
paraprotéinémie monoclonale	Is a	False	Monoclonal gammopathy (clinical)	Inferred relationship	Some
TEMPI syndrome is a rare multi-systemic disease characterized by the presence of Telangiectasias, Erythrocytosis with elevated erythropoietin levels, Monoclonal gammopathy, Perinephric-fluid collections, and Intrapulmonary shunting.	Is a	True	Monoclonal gammopathy (clinical)	Inferred relationship	Some
A rare, secondary glomerular disease characterized by proteinuria, dysproteinemias, nephrotic syndrome, and nodular glomerulopathy leading to renal failure, with or without extra-renal manifestations. The renal biopsy shows typical deposits of monoclonal immunoglobulins that do not show a fibrillar organization and are negative for Congo red staining. Associated signs and symptoms depend on the involvement of other organs, liver, heart, nerve fibers, gastrointestinal tract, or skin.	Is a	True	Monoclonal gammopathy (clinical)	Inferred relationship	Some
Scleredema associated with paraproteinemia (disorder)	Associated with	True	Monoclonal gammopathy (clinical)	Inferred relationship	Some	2
A rare hematologic disease characterized by symptoms of mast cell activation in the absence of cutaneous findings, as well as absence of diagnostic criteria of systemic mastocytosis with tryptase levels of less than 20 ng/ml and normal to low burden of mast cells. Bone marrow biopsy reveals the presence of monoclonal mast cells carrying the KIT D816V mutation and/or expressing CD25. Patients present with recurrent episodes of flushing, headache, hypotension, abdominal cramping, nausea, diarrhea, cardiac arrhythmias, bronchoconstriction, and bleeding diathesis, among others.	Is a	False	Monoclonal gammopathy (clinical)	Inferred relationship	Some

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
174679017	Monoclonal gammopathy (clinical)	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
617774019	Monoclonal gammopathy (disorder)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2659691014	Monoclonal gammopathy	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3763340012	Monoclonal paraproteinaemia	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3763341011	Monoclonal paraproteinemia	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
948501000195114	gammopatia monoclonale	it	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
3398134010	gammapathie monoclonale	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
384131000274119	Monoklonale Gammopathie	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
443731000274119	Monoklonale Hypergammaglobulinämie	de	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module