Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Subungual corn |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
Soft corn |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Corn of toe |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Hard corn |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Corn - lesion |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Neurovascular corn |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Interdigital corn |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
Intractable plantar keratoma |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
Vascular corn |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Seed corn |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Durlachers corn |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Corns NOS |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Intractable plantar keratoma |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
Interdigital corn |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
Fibrous corn (disorder) |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
4 |
Soft corn |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
3 |
Hard corn |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
3 |
Corn - lesion |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
3 |
Neurovascular corn |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
3 |
Vascular corn |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
3 |
Seed corn |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
3 |
Durlachers corn |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
3 |
Subungual corn |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
4 |
Corn of toe |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
4 |
Interdigital corn |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
3 |
Intractable plantar keratoma |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
3 |
Fibrous corn (disorder) |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Striate palmoplantar keratoderma is an isolated, focal, hereditary palmoplantar keratoderma characterized by linear hyperkeratosis along the flexor aspect of the fingers and on palms, as well as focal hyperkeratosis of the plantar skin. Patients present with painful thickening of the skin on palms and soles, with occasional fissuring, blistering and hyperhidrosis. Rarely, hyperkeratosis on other areas may be seen (knees, dorsal aspects of the digits). Histopathologically, widened intercellular spaces between keratinocytes are observed. |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Focal palmoplantar and gingival keratoderma is a very rare form of focal palmoplantar keratoderma characterized by painful circumscribed hyperkeratotic lesions on weight-bearing areas of soles, moderate focal hyperkeratosis of palmar pressure-related areas and an asymptomatic leukokeratosis confined to labial- and lingual- attached gingiva. Additional occasional features may include hyperhidrosis, follicular keratosis and extended oral mucosa involvement. |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
Intractable plantar keratoma |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Focal acral hyperkeratosis (disorder) |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
Focal acral hyperkeratosis (disorder) |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Focal palmoplantar and gingival keratoderma is a very rare form of focal palmoplantar keratoderma characterized by painful circumscribed hyperkeratotic lesions on weight-bearing areas of soles, moderate focal hyperkeratosis of palmar pressure-related areas and an asymptomatic leukokeratosis confined to labial- and lingual- attached gingiva. Additional occasional features may include hyperhidrosis, follicular keratosis and extended oral mucosa involvement. |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
3 |
Circumscribed palmoplantar keratoderma |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Circumscribed palmoplantar keratoderma |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
Keratoderma areata |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
Keratoderma areata |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
3 |
Keratoderma with pachyonychia congenita |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
Keratoderma with pachyonychia congenita |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
3 |
Palmoplantar hyperkeratosis sclerodactyly syndrome (disorder) |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
Palmoplantar hyperkeratosis sclerodactyly syndrome (disorder) |
Associated morphology |
False |
Focal hyperkeratosis |
Inferred relationship |
Some |
3 |
Keratoderma climactericum |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Subungual corn |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Interdigital corn |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Focal palmoplantar and gingival keratoderma is a very rare form of focal palmoplantar keratoderma characterized by painful circumscribed hyperkeratotic lesions on weight-bearing areas of soles, moderate focal hyperkeratosis of palmar pressure-related areas and an asymptomatic leukokeratosis confined to labial- and lingual- attached gingiva. Additional occasional features may include hyperhidrosis, follicular keratosis and extended oral mucosa involvement. |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
Striate palmoplantar keratoderma is an isolated, focal, hereditary palmoplantar keratoderma characterized by linear hyperkeratosis along the flexor aspect of the fingers and on palms, as well as focal hyperkeratosis of the plantar skin. Patients present with painful thickening of the skin on palms and soles, with occasional fissuring, blistering and hyperhidrosis. Rarely, hyperkeratosis on other areas may be seen (knees, dorsal aspects of the digits). Histopathologically, widened intercellular spaces between keratinocytes are observed. |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
A rare genetic skin disease characterized by generalized skin peeling or superficial blisters without scarring, leukonychia, acral punctate keratoses coalescing into focal keratoderma on the weight-bearing areas, painful angular cheilitis, and knuckle pads with multiple hyperkeratotic micropapules. The skin appears dry and scaly with superficial exfoliation and underlying erythema. Histopathologic examination of affected skin areas is not specific and shows hyperkeratosis, acanthosis, and occasional intraepidermal clefting with irregular acantholysis. |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
A rare genetic skin disease characterized by generalized skin peeling or superficial blisters without scarring, leukonychia, acral punctate keratoses coalescing into focal keratoderma on the weight-bearing areas, painful angular cheilitis, and knuckle pads with multiple hyperkeratotic micropapules. The skin appears dry and scaly with superficial exfoliation and underlying erythema. Histopathologic examination of affected skin areas is not specific and shows hyperkeratosis, acanthosis, and occasional intraepidermal clefting with irregular acantholysis. |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
A rare hereditary palmoplantar keratoderma characterized by focal hyperkeratotic lesions on the palms and soles. Histopathologic examination reveals prominent hyperkeratosis, thickened stratum spinosum with reduced stratum granulosum, disadhesion of cells in the suprabasal layers, elongation of rete ridges, and sparse lymphocyte infiltration in the dermis. |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |
A rare hereditary palmoplantar keratoderma characterized by focal hyperkeratotic lesions on the palms and soles. Histopathologic examination reveals prominent hyperkeratosis, thickened stratum spinosum with reduced stratum granulosum, disadhesion of cells in the suprabasal layers, elongation of rete ridges, and sparse lymphocyte infiltration in the dermis. |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
A rare genetic disease characterised by thickening of the skin on palms and soles restricted to areas of weight bearing and/or friction (focal, non-epidermolytic palmoplantar keratoderma) and oral and oesophageal leucokeratosis, associated with a very high lifetime risk of developing squamous cell carcinoma of the oesophagus. The skin lesions appear in childhood and can be complicated by fissuring and infection. |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
2 |
A rare genetic disease characterised by thickening of the skin on palms and soles restricted to areas of weight bearing and/or friction (focal, non-epidermolytic palmoplantar keratoderma) and oral and oesophageal leucokeratosis, associated with a very high lifetime risk of developing squamous cell carcinoma of the oesophagus. The skin lesions appear in childhood and can be complicated by fissuring and infection. |
Associated morphology |
True |
Focal hyperkeratosis |
Inferred relationship |
Some |
1 |