Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Pneumonia due to parasitic infestation |
Finding site |
False |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
2 |
Capillaria aerophila chest infection (disorder) |
Finding site |
False |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
4 |
Pneumonia caused by Ascaris |
Finding site |
False |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
2 |
Cryptogenic organizing pneumonia (disorder) |
Finding site |
False |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
6 |
Malarial shock lung |
Finding site |
False |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
3 |
Malarial shock lung |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Congenital nephrotic syndrome, interstitial lung disease, epidermolysis bullosa syndrome |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
2 |
Interstitial lung disease due to systemic disease |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Interstitial lung disease due to granulomatous disease (disorder) |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Interstitial lung disease due to metabolic disease (disorder) |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Interstitial lung disease co-occurrent and due to systemic vasculitis (disorder) |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
2 |
A partial autosomal monosomy characterized clinically by lethal pulmonary disease that presents as severe respiratory distress and refractory pulmonary hypertension within a few hours after birth and typically results in death from respiratory failure within the first months of life. Characteristic histological features of lung tissue include paucity of alveolar wall capillaries, alveolar wall thickening, muscular hypertrophy of the pulmonary arteries, and malposition of the small pulmonary veins. Various additional congenital malformations may be associated, mostly gastrointestinal (intestinal malrotation and atresias, anular pancreas), genitourinary (dilatation of urinary tracts, duplicated uterus) and cardiovascular anomalies (hypoplastic left heart and other congenital heart defects). |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
3 |
Acute respiratory distress in newborn with surfactant disorder |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Genetic disorder of surfactant dysfunction |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Chronic respiratory distress with surfactant metabolism deficiency is a rare, genetic, primary interstitial lung disease with a highly variable clinical presentation, ranging from neonatal respiratory distress syndrome to mild to severe interstitial lung disease (typical symptoms include cough, tachypnea, hypoxia, clubbing, crackles, failure to thrive). Lung biopsy reveals diffuse alveolar damage, interstitial thickening with inflammatory infiltrates, fibroblast proliferation, collagen deposition, and multiple foci of fibrosis, alveolar type II cell hyperplasia, abundant foamy alveolar macrophages and granular lipoproteic material in the alveolar lumen. Imaging shows cystic spaces and ground-glass opacities that are typically homogenously diffuse. |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
2 |
Acute exacerbation of idiopathic pulmonary fibrosis (disorder) |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
2 |
Idiopathic pulmonary hemosiderosis |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Perinatal interstitial emphysema |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Acute respiratory distress syndrome due to disease caused by severe acute respiratory syndrome coronavirus 2 (disorder) |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Fetal interstitial neoplasm of lung |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Interstitial lung disease due to juvenile polymyositis |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Interstitial pneumonitis with autoimmune features |
Finding site |
False |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Interstitial pulmonary fibrosis due to inhalation of substance |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Interstitial pulmonary fibrosis due to inhalation of drug |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
fibrose pulmonaire chronique causée par des vapeurs chimiques |
Finding site |
False |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
A rare disease, manifesting with idiopathic pulmonary fibrosis, hepatic nodular regenerative hyperplasia leading to portal hypertension and thrombocytopenia due to bone marrow hypoplasia. The condition was associated with 100% mortality. |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
2 |
A rare idiopathic interstitial pneumonia characterized by prominent subpleural and parenchymal fibroelastosis and pleural fibrosis, predominantly involving the upper lobes. Signs and symptoms include non-productive cough, dyspnea, and recurrent respiratory infections. Pneumothorax is a frequently reported complication. Pulmonary function test reveals a restrictive pattern and reduced diffusing capacity. Computed tomography shows pleural thickening with signs of fibrosis (traction bronchiectasis, architectural distortion, and loss of volume), and reticulation. |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
2 |
A rare genetic interstitial lung disease characterized by diffuse lung disease of variable phenotype ranging from severe respiratory insufficiency in infancy to asymptomatic adults, due to surfactant protein C deficiency. Typical presentation in infancy includes dyspnea, cough, wheezing, and gradual cyanosis, with or without failure to thrive. Radiological findings include diffuse ground-glass opacities in neonates, later interstitial thickening associated with lung hyperinflation, intraparenchymal/subpleural cysts, honeycombing, subpleural nodules, or bronchiectasis. Infiltrates and air leaks are frequent complications. |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
A rare genetic respiratory disease characterized by a variable clinical outcome ranging from a fatal respiratory distress syndrome in the neonatal period to chronic interstitial lung disease developing in infancy or childhood with chronic cough, rapid breathing, shortness of breath and recurrent pulmonary infections. Clinical manifestations of respiratory failure include grunting, intercostal retractions, nasal flaring, cyanosis, and progressive dyspnea. |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
A rare genetic systemic or rheumatologic disease characterized by interstitial lung disease (often with pulmonary hemorrhage) and inflammatory arthritis, associated with high-titer autoantibodies (including anti-nuclear and anti-neutrophil cytoplasmic antibodies, and rheumatoid factor). Patients present from infancy to adolescence with tachypnea, cough, hemoptysis, and/or joint pain. Some patients may also develop glomerular disease. |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
2 |
A rare, genetic interstitial lung disease characterised by accumulation of lipoproteins in the pulmonary alveoli leading to restrictive lung disease and respiratory failure. Patients present with dyspnoea, tachypnoea, cough, failure to thrive, and digital clubbing. Liver disease have been described in some cases including hepatomegaly, steatosis, fibrosis or cirrhosis. |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
3 |
Diffuse pulmonary meningotheliomatosis (disorder) |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Interstitial lung disease due to vaping (disorder) |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Interstitial lung disorder due to dabbing |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Acute respiratory distress syndrome due to dabbing |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Acute respiratory distress syndrome due to vaping (disorder) |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Interstitial lung disease due to and following radiotherapy (disorder) |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
Chronic pulmonary fibrosis caused by vapor (disorder) |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
1 |
A rare interstitial lung disease characterized by early-onset, severe, progressive lung disease manifesting by respiratory distress, neurological symptoms including axial hypotonia, developmental delay, irritability, dystonia, poor visual contact and seizures, and variable multisystemic involvement including malabsorption, progressive growth failure, recurrent infections, chronic hemolytic anemia and liver dysfunction. Kidney dysfunction, cardiac involvement including cardiomegaly and cardiac hypertrophy, decreased vision and strabismus have also been reported. Lung fibrosis may cause death in infancy from respiratory failure. |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
2 |
Lung disease, immunodeficiency, chromosome breakage syndrome (disorder) |
Finding site |
True |
Structure of interstitial tissue of lung |
Inferred relationship |
Some |
2 |