1217200005: Larotrectinib sulfate (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Larotrectinib sulfate

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Larotrectinib sulfate
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Pyrazole derivative\Larotrectinib sulfate

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\...

\Pyrimidine and/or pyrimidine derivative\Pyrimidine\Larotrectinib sulfate

\Azole\Pyrazole and/or pyrazole derivative (substance)\Pyrazole derivative\Larotrectinib sulfate

\Organic compound\Organic cyclic compound\Heterocyclic compound\Pyrimidine and/or pyrimidine derivative\Pyrimidine\Larotrectinib sulfate
\Organic compound\Organic cyclic compound\Heterocyclic compound\Azole\Pyrazole and/or pyrazole derivative (substance)\Pyrazole derivative\Larotrectinib sulfate
\Organic compound\Organic nitrogen compound\Pyrimidine and/or pyrimidine derivative\Pyrimidine\Larotrectinib sulfate
\Organic compound\Organic nitrogen compound\Azole\Pyrazole and/or pyrazole derivative (substance)\Pyrazole derivative\Larotrectinib sulfate
\Organic compound\Hydrocarbon\Pyrazole and/or pyrazole derivative (substance)\Pyrazole derivative\Larotrectinib sulfate

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 30-Apr 2022. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

5035109012 Larotrectinib sulfate en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

5035110019 Larotrectinib sulfate (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Larotrectinib sulfate	Is a	Pyrazole derivative	true	Inferred relationship	Some
Larotrectinib sulfate	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some
Larotrectinib sulfate	Is a	Protein-tyrosine kinase inhibitor	true	Inferred relationship	Some
Larotrectinib sulfate	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Larotrectinib sulfate	Is a	Pyrimidine	true	Inferred relationship	Some
Larotrectinib sulfate	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Protein-tyrosine kinase inhibitor (disposition)	true	Inferred relationship	Some
Larotrectinib sulfate	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	Larotrectinib (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Larotrectinib (as larotrectinib sulfate) 20 mg/mL oral solution	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Larotrectinib sulfate	Inferred relationship	Some	1
Larotrectinib (as larotrectinib sulfate) 100 mg oral capsule	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Larotrectinib sulfate	Inferred relationship	Some	1
Product containing precisely larotrectinib (as larotrectinib sulfate) 25 milligram/1 each conventional release oral capsule (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Larotrectinib sulfate	Inferred relationship	Some	1

This concept is not in any reference sets