126223008: Calcium folinate (substance)

SNOMED CT Concept\Substance\...

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antidote (substance)\Calcium folinate
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Vitamin\Water-soluble vitamin\Vitamin B and/or vitamin B derivative (substance)\Calcium folinate

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Heterocyclic compound\Pteridine\Pterins\Calcium folinate

\Biological substance\Nutrients\Vitamin\Water-soluble vitamin\Vitamin B and/or vitamin B derivative (substance)\Calcium folinate

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Calcium folinate	Is a	Dihydrofolic acid	false	Inferred relationship	Some
Calcium folinate	Is a	Antidote (substance)	true	Inferred relationship	Some
Calcium folinate	Is a	Pterins	true	Inferred relationship	Some
Calcium folinate	Is a	Vitamin B and/or vitamin B derivative (substance)	true	Inferred relationship	Some
Calcium folinate	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	Folinic acid (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing calcium leucovorin	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some	1
Product containing precisely calcium folinate 15 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some
Leucovorin Calcium 350mg powder for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some
Leucovorin Calcium 200mg powder for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some
Leucovorin Calcium 50mg powder for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some
Leucovorin Calcium 100mg powder for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some
Leucovorin Calcium 500mg powder for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some
Product containing precisely calcium folinate 5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some
Levoleucovorin calcium (substance)	Is a	False	Calcium folinate	Inferred relationship	Some
Product containing calcium leucovorin in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some	1
Product containing calcium leucovorin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some	1
Leukovorin rescue	Direct substance	False	Calcium folinate	Inferred relationship	Some	1
Leukovorin rescue	Direct substance	True	Calcium folinate	Inferred relationship	Some	1
Product containing precisely calcium folinate 15 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some	1
Product containing precisely calcium folinate 15 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Calcium folinate	Inferred relationship	Some	1
Product containing precisely calcium folinate 5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some	1
Product containing precisely calcium folinate 5 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Calcium folinate	Inferred relationship	Some	1
Leucovorin calcium pentahydrate (substance)	Is a	False	Calcium folinate	Inferred relationship	Some
Product containing precisely calcium folinate 5 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Calcium folinate	Inferred relationship	Some	1
Product containing precisely calcium folinate 15 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Calcium folinate	Inferred relationship	Some	1
Product containing only calcium leucovorin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some	1
Product containing only calcium leucovorin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some	1
Product containing only calcium leucovorin in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Calcium folinate	Inferred relationship	Some	1
Leucovorin calcium pentahydrate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Calcium folinate	Inferred relationship	Some
Product containing precisely folinic acid (as calcium folinate) 10 milligram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Calcium folinate	Inferred relationship	Some	1
Product containing precisely folinic acid (as calcium folinate) 7.5 milligram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Calcium folinate	Inferred relationship	Some	1
Product containing precisely folinic acid (as calcium folinate) 15 milligram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Calcium folinate	Inferred relationship	Some	1
Product containing precisely folinic acid (as calcium folinate) 3 milligram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Calcium folinate	Inferred relationship	Some	1

Reference Sets

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Id	Description	Lang	Type	Status	Case?	Module
37198019	Calcium leucovorin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2696103014	Calcium folinate	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4570195018	Calcium folinate (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
52061000195112	calcio folinato	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
15171000188111	folinate de calcium	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
66361000195115	Calcium folinat	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
236171000195112	Calciumfolinat	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module