1362026000: Nodal T-follicular helper cell lymphoma follicular type (disorder)

SNOMED CT Concept\Clinical finding (finding)\Disease\...

\Disorder of hematopoietic cell proliferation (disorder)\Lymphoproliferative disorder\Lymphoreticular tumour\...

\T-cell AND/OR NK-cell neoplasm\T-cell lymphoma (disorder)\A rare T-cell non-Hodgkin lymphoma characterised by generalised lymphadenopathy and predominantly follicular or perifollicular growth pattern, consistent with the expression of T-follicular helper markers. Affected individuals distinctly lack histologic features (such as proliferation of high endothelial venules and expanded follicular dendritic meshworks) typically associated to angioimmunoblastic T-cell lymphoma. It affects elderly individuals (mostly at the sixth decade of life) that present with advanced-stage disease. Majority of the cases have disseminated nodal involvement, whereas involvement of extranodal sites including skin, liver, spleen and bone marrow are also reported. Patients may therefore develop skin rash and immune manifestations.

\Malignant lymphoma (disorder)\Non-Hodgkin's lymphoma (clinical)\T-cell lymphoma (disorder)\A rare T-cell non-Hodgkin lymphoma characterised by generalised lymphadenopathy and predominantly follicular or perifollicular growth pattern, consistent with the expression of T-follicular helper markers. Affected individuals distinctly lack histologic features (such as proliferation of high endothelial venules and expanded follicular dendritic meshworks) typically associated to angioimmunoblastic T-cell lymphoma. It affects elderly individuals (mostly at the sixth decade of life) that present with advanced-stage disease. Majority of the cases have disseminated nodal involvement, whereas involvement of extranodal sites including skin, liver, spleen and bone marrow are also reported. Patients may therefore develop skin rash and immune manifestations.

\Neoplasm and/or hamartoma (disorder)\Neoplastic disease\...

\Neoplasm of hematopoietic cell type (disorder)\Lymphoreticular tumour\T-cell AND/OR NK-cell neoplasm\T-cell lymphoma (disorder)\A rare T-cell non-Hodgkin lymphoma characterised by generalised lymphadenopathy and predominantly follicular or perifollicular growth pattern, consistent with the expression of T-follicular helper markers. Affected individuals distinctly lack histologic features (such as proliferation of high endothelial venules and expanded follicular dendritic meshworks) typically associated to angioimmunoblastic T-cell lymphoma. It affects elderly individuals (mostly at the sixth decade of life) that present with advanced-stage disease. Majority of the cases have disseminated nodal involvement, whereas involvement of extranodal sites including skin, liver, spleen and bone marrow are also reported. Patients may therefore develop skin rash and immune manifestations.
\Neoplasm of hematopoietic cell type (disorder)\Lymphoreticular tumour\Malignant lymphoma (disorder)\Non-Hodgkin's lymphoma (clinical)\T-cell lymphoma (disorder)\A rare T-cell non-Hodgkin lymphoma characterised by generalised lymphadenopathy and predominantly follicular or perifollicular growth pattern, consistent with the expression of T-follicular helper markers. Affected individuals distinctly lack histologic features (such as proliferation of high endothelial venules and expanded follicular dendritic meshworks) typically associated to angioimmunoblastic T-cell lymphoma. It affects elderly individuals (mostly at the sixth decade of life) that present with advanced-stage disease. Majority of the cases have disseminated nodal involvement, whereas involvement of extranodal sites including skin, liver, spleen and bone marrow are also reported. Patients may therefore develop skin rash and immune manifestations.
\Neoplasm of hematopoietic cell type (disorder)\Malignant neoplasm of lymphoid, hematopoietic and/or related tissue (disorder)\Malignant lymphoma (disorder)\Non-Hodgkin's lymphoma (clinical)\T-cell lymphoma (disorder)\A rare T-cell non-Hodgkin lymphoma characterised by generalised lymphadenopathy and predominantly follicular or perifollicular growth pattern, consistent with the expression of T-follicular helper markers. Affected individuals distinctly lack histologic features (such as proliferation of high endothelial venules and expanded follicular dendritic meshworks) typically associated to angioimmunoblastic T-cell lymphoma. It affects elderly individuals (mostly at the sixth decade of life) that present with advanced-stage disease. Majority of the cases have disseminated nodal involvement, whereas involvement of extranodal sites including skin, liver, spleen and bone marrow are also reported. Patients may therefore develop skin rash and immune manifestations.

\Malignant neoplastic disease (disorder)\Malignant neoplasm of lymphoid, hematopoietic and/or related tissue (disorder)\Malignant lymphoma (disorder)\Non-Hodgkin's lymphoma (clinical)\T-cell lymphoma (disorder)\A rare T-cell non-Hodgkin lymphoma characterised by generalised lymphadenopathy and predominantly follicular or perifollicular growth pattern, consistent with the expression of T-follicular helper markers. Affected individuals distinctly lack histologic features (such as proliferation of high endothelial venules and expanded follicular dendritic meshworks) typically associated to angioimmunoblastic T-cell lymphoma. It affects elderly individuals (mostly at the sixth decade of life) that present with advanced-stage disease. Majority of the cases have disseminated nodal involvement, whereas involvement of extranodal sites including skin, liver, spleen and bone marrow are also reported. Patients may therefore develop skin rash and immune manifestations.

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 01-Mar 2025. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

5443915011 A rare T-cell non-Hodgkin lymphoma characterized by generalized lymphadenopathy and predominantly follicular or perifollicular growth pattern, consistent with the expression of T-follicular helper markers. Affected individuals distinctly lack histologic features (such as proliferation of high endothelial venules and expanded follicular dendritic meshworks) typically associated to angioimmunoblastic T-cell lymphoma. It affects elderly individuals (mostly at the sixth decade of life) that present with advanced-stage disease. Majority of the cases have disseminated nodal involvement, whereas involvement of extranodal sites including skin, liver, spleen and bone marrow are also reported. Patients may therefore develop skin rash and immune manifestations. en Definition Active Entire term case sensitive (core metadata concept) SNOMED CT core

5443916012 A rare T-cell non-Hodgkin lymphoma characterised by generalised lymphadenopathy and predominantly follicular or perifollicular growth pattern, consistent with the expression of T-follicular helper markers. Affected individuals distinctly lack histologic features (such as proliferation of high endothelial venules and expanded follicular dendritic meshworks) typically associated to angioimmunoblastic T-cell lymphoma. It affects elderly individuals (mostly at the sixth decade of life) that present with advanced-stage disease. Majority of the cases have disseminated nodal involvement, whereas involvement of extranodal sites including skin, liver, spleen and bone marrow are also reported. Patients may therefore develop skin rash and immune manifestations. en Definition Active Entire term case sensitive (core metadata concept) SNOMED CT core

5443908015 Follicular helper T-cell lymphoma, follicular type en Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT core

5443909011 Nodal T-follicular helper cell lymphoma follicular type (disorder) en Fully specified name Active Only initial character case insensitive (core metadata concept) SNOMED CT core

5443910018 nTFHL-F - nodal T-follicular helper cell lymphoma follicular type en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

5443911019 Nodal T-cell lymphoma with TFH phenotype en Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT core

5443912014 Nodal T-follicular helper cell lymphoma follicular type en Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
A rare T-cell non-Hodgkin lymphoma characterised by generalised lymphadenopathy and predominantly follicular or perifollicular growth pattern, consistent with the expression of T-follicular helper markers. Affected individuals distinctly lack histologic features (such as proliferation of high endothelial venules and expanded follicular dendritic meshworks) typically associated to angioimmunoblastic T-cell lymphoma. It affects elderly individuals (mostly at the sixth decade of life) that present with advanced-stage disease. Majority of the cases have disseminated nodal involvement, whereas involvement of extranodal sites including skin, liver, spleen and bone marrow are also reported. Patients may therefore develop skin rash and immune manifestations.	Is a	T-cell lymphoma (disorder)	true	Inferred relationship	Some
A rare T-cell non-Hodgkin lymphoma characterised by generalised lymphadenopathy and predominantly follicular or perifollicular growth pattern, consistent with the expression of T-follicular helper markers. Affected individuals distinctly lack histologic features (such as proliferation of high endothelial venules and expanded follicular dendritic meshworks) typically associated to angioimmunoblastic T-cell lymphoma. It affects elderly individuals (mostly at the sixth decade of life) that present with advanced-stage disease. Majority of the cases have disseminated nodal involvement, whereas involvement of extranodal sites including skin, liver, spleen and bone marrow are also reported. Patients may therefore develop skin rash and immune manifestations.	Associated morphology	Follicular T-cell lymphoma (morphologic abnormality)	true	Inferred relationship	Some	1

Inbound Relationships

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Component annotation with string value reference set (foundation metadata concept)

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Id	Description	Lang	Type	Status	Case?	Module
5443915011	A rare T-cell non-Hodgkin lymphoma characterized by generalized lymphadenopathy and predominantly follicular or perifollicular growth pattern, consistent with the expression of T-follicular helper markers. Affected individuals distinctly lack histologic features (such as proliferation of high endothelial venules and expanded follicular dendritic meshworks) typically associated to angioimmunoblastic T-cell lymphoma. It affects elderly individuals (mostly at the sixth decade of life) that present with advanced-stage disease. Majority of the cases have disseminated nodal involvement, whereas involvement of extranodal sites including skin, liver, spleen and bone marrow are also reported. Patients may therefore develop skin rash and immune manifestations.	en	Definition	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
5443916012	A rare T-cell non-Hodgkin lymphoma characterised by generalised lymphadenopathy and predominantly follicular or perifollicular growth pattern, consistent with the expression of T-follicular helper markers. Affected individuals distinctly lack histologic features (such as proliferation of high endothelial venules and expanded follicular dendritic meshworks) typically associated to angioimmunoblastic T-cell lymphoma. It affects elderly individuals (mostly at the sixth decade of life) that present with advanced-stage disease. Majority of the cases have disseminated nodal involvement, whereas involvement of extranodal sites including skin, liver, spleen and bone marrow are also reported. Patients may therefore develop skin rash and immune manifestations.	en	Definition	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
5443908015	Follicular helper T-cell lymphoma, follicular type	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
5443909011	Nodal T-follicular helper cell lymphoma follicular type (disorder)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
5443910018	nTFHL-F - nodal T-follicular helper cell lymphoma follicular type	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
5443911019	Nodal T-cell lymphoma with TFH phenotype	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
5443912014	Nodal T-follicular helper cell lymphoma follicular type	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core