1363418009: Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)

SNOMED CT Concept\Clinical finding (finding)\...

\Head finding (finding)\Finding of head region\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior chamber of eye\Disorder of iridocorneal angle\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of cornea\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of uveal tract\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Globe finding\Anterior segment finding (finding)\Iris finding\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Globe finding\Anterior segment finding (finding)\Anterior chamber finding (finding)\Disorder of anterior chamber of eye\Disorder of iridocorneal angle\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Globe finding\Anterior segment finding (finding)\Anterior chamber finding (finding)\Finding of angle of anterior chamber\Disorder of iridocorneal angle\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Globe finding\Anterior segment finding (finding)\Corneal finding (finding)\Disorder of cornea\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Globe finding\Anterior segment finding (finding)\Disorder of anterior segment of eye\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Globe finding\Anterior segment finding (finding)\Disorder of anterior segment of eye\Disorder of anterior chamber of eye\Disorder of iridocorneal angle\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Globe finding\Anterior segment finding (finding)\Disorder of anterior segment of eye\Disorder of cornea\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Globe finding\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Globe finding\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Globe finding\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Globe finding\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior chamber of eye\Disorder of iridocorneal angle\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Globe finding\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of cornea\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Finding of head region\Globe finding\Disorder of eye proper (disorder)\Disorder of uveal tract\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Disorder of head (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Disorder of head (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Disorder of head (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Disorder of head (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior chamber of eye\Disorder of iridocorneal angle\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Disorder of head (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of cornea\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Head finding (finding)\Disorder of head (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of uveal tract\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)

\Eye / vision finding\Globe finding\Anterior segment finding (finding)\Iris finding\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Globe finding\Anterior segment finding (finding)\Anterior chamber finding (finding)\Disorder of anterior chamber of eye\Disorder of iridocorneal angle\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Globe finding\Anterior segment finding (finding)\Anterior chamber finding (finding)\Finding of angle of anterior chamber\Disorder of iridocorneal angle\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Globe finding\Anterior segment finding (finding)\Corneal finding (finding)\Disorder of cornea\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Globe finding\Anterior segment finding (finding)\Disorder of anterior segment of eye\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Globe finding\Anterior segment finding (finding)\Disorder of anterior segment of eye\Disorder of anterior chamber of eye\Disorder of iridocorneal angle\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Globe finding\Anterior segment finding (finding)\Disorder of anterior segment of eye\Disorder of cornea\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Globe finding\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Globe finding\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Globe finding\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Globe finding\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior chamber of eye\Disorder of iridocorneal angle\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Globe finding\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of cornea\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Globe finding\Disorder of eye proper (disorder)\Disorder of uveal tract\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Visual system disorder (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Visual system disorder (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Visual system disorder (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Visual system disorder (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior chamber of eye\Disorder of iridocorneal angle\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Visual system disorder (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of cornea\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Eye / vision finding\Visual system disorder (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of uveal tract\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)

\Disease\Disorder of sensory organ (disorder)\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of sensory organ (disorder)\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of sensory organ (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of sensory organ (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior chamber of eye\Disorder of iridocorneal angle\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of sensory organ (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of cornea\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of sensory organ (disorder)\Disorder of eye proper (disorder)\Disorder of uveal tract\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of body system\Visual system disorder (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of body system\Visual system disorder (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of body system\Visual system disorder (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of body system\Visual system disorder (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior chamber of eye\Disorder of iridocorneal angle\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of body system\Visual system disorder (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of cornea\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of body system\Visual system disorder (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of uveal tract\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of head (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of head (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Anomaly of eye (disorder)\Lesion of eye (disorder)\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of head (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of head (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of anterior chamber of eye\Disorder of iridocorneal angle\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of head (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of anterior segment of eye\Disorder of cornea\Lesion of cornea (disorder)\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)
\Disease\Disorder of head (disorder)\Disorder of eye region (disorder)\Disorder of eye proper (disorder)\Disorder of uveal tract\Disorder of anterior uveal tract (disorder)\Disorder of iris\Lesion of iris (disorder)\Adhesions of iris\Anterior synechiae\Peripheral anterior synechiae (disorder)\Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)

Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 01-Apr 2025. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

5448817018 Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

5448818011 Peripheral anterior synechiae in superior quadrant of angle en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

5448819015 Peripheral anterior synechiae in superior quadrant of iridocorneal angle en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)	Is a	Peripheral anterior synechiae (disorder)	true	Inferred relationship	Some
Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)	Finding site	Superior quadrant of iridocorneal angle	true	Inferred relationship	Some	1
Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)	Associated morphology	Synechia	true	Inferred relationship	Some	1
Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)	Finding site	Structure of peripheral iris (body structure)	true	Inferred relationship	Some	2
Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)	Associated morphology	Synechia	true	Inferred relationship	Some	2
Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)	Finding site	Corneal structure	true	Inferred relationship	Some	3
Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)	Associated morphology	Synechia	true	Inferred relationship	Some	3

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Peripheral anterior synechiae in superior quadrant of iridocorneal angle of right eye (disorder)	Is a	True	Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)	Inferred relationship	Some
Peripheral anterior synechiae in superior quadrant of angle of left eye	Is a	True	Peripheral anterior synechiae in superior quadrant of iridocorneal angle (disorder)	Inferred relationship	Some

This concept is not in any reference sets