Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Deposition of calcium pyrophosphate crystals, calcified structure (morphologic abnormality) |
Is a |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
|
Calcification of intervertebral cartilage AND/OR disc of cervical region |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of wrist joint (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of hip joint (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of elbow joint (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of knee joint (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of joint of hand (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of joint of shoulder region (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of intervertebral cartilage AND/OR disc of lumbar region |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of intervertebral cartilage AND/OR disc |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of spleen |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of joint of ankle AND/OR foot (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of intervertebral cartilage AND/OR disc of thoracic region |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of joint of pelvis (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of elbow joint (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of hip joint (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of joint of hand (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of knee joint (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of wrist joint (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of joint of shoulder region (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of joint of ankle AND/OR foot (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of coronary artery (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of muscle (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of joint of pelvis (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcium deposits in tendon (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of coronary artery (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcium deposits in tendon (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of muscle (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Diffuse nodular calcifications of breast |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
2 |
Rheumatic mitral valve annular calcification |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
2 |
Aortic valve calcification |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
2 |
Calcification of pulmonary valve (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of pulmonary valve annulus (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of truncal valve (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of common atrioventricular valve (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of right atrioventricular (not morphologically tricuspid) valve (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of left atrioventricular (not morphologically mitral) valve (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of tricuspid valve |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of mitral valve (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of aortic valve annulus (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Mammographic calcification of breast |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
3 |
Diffuse linear pulp calcification (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
2 |
Calcification of stylohyoid ligament (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcification of laryngeal cartilage |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcific stenosis |
Is a |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
|
Bartter syndrome antenatal type 1 (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
4 |
Bartter syndrome type 4 |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
4 |
Bartter syndrome antenatal type 2 (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
4 |
Bartter's syndrome with hypercalciuria and nephrocalcinosis |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
4 |
Chondrocalcinosis of joint of shoulder region (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
2 |
Pinnal calcification |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
3 |
Cerebroretinal microangiopathy with calcifications and cysts |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
3 |
Pulp stones |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
2 |
Chondrocalcinosis of elbow due to disorder of calcium metabolism (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
3 |
Chondrocalcinosis of hand due to disorder of calcium metabolism |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
3 |
Chondrocalcinosis of hip joint due to disorder of calcium metabolism (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
4 |
Calciphylaxis |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
A rare, genetic, renal tubular disease characterized by nephrogenic diabetes insipidus, intracerebral calcifications, intellectual disability, short stature and facial dysmorphism. There have been no further descriptions in the literature since 1990. |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
3 |
A rare, life-threatening, non-inflammatory vasculopathy characterized clinically by progressive and painful skin lesions associated with calcification of cutaneous arterial microvessels. Calciphylaxis predominantly affects patients with end-stage kidney disease (ESKD) on dialysis. |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Hereditary arterial and articular multiple calcification syndrome is a very rare genetic vascular disease of autosomal recessive inheritance, described in less than 20 patients to date, characterized by adult-onset (as early as the second decade of life) isolated calcification of the arteries of the lower extremities (including the iliac, femoral, and tibial arteries) as well as the capsule joints of the fingers, wrists, ankles and feet, and that usually manifests with mild paresthesias of the lower extremities, intense joint pain and swelling, and early onset arthritis of affected joints. |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
2 |
Hereditary arterial and articular multiple calcification syndrome is a very rare genetic vascular disease of autosomal recessive inheritance, described in less than 20 patients to date, characterized by adult-onset (as early as the second decade of life) isolated calcification of the arteries of the lower extremities (including the iliac, femoral, and tibial arteries) as well as the capsule joints of the fingers, wrists, ankles and feet, and that usually manifests with mild paresthesias of the lower extremities, intense joint pain and swelling, and early onset arthritis of affected joints. |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
3 |
Symmetrical thalamic calcifications are clinically distinguished by a low Apgar score, spasticity or marked hypotonia, weak or absent cry, poor feeding, and facial diplegia or weakness. |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
2 |
Bartter syndrome type 4a (disorder) |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
4 |
A rare, inherited disorder characterized by widespread calcifications of basal ganglia and cortex, developmental delay, small stature, retinopathy and microcephaly. The absence of progressive deterioration of the neurological functions is characteristic of the disease. |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
3 |
A rare, inherited disorder characterized by widespread calcifications of basal ganglia and cortex, developmental delay, small stature, retinopathy and microcephaly. The absence of progressive deterioration of the neurological functions is characteristic of the disease. |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
4 |
Craniosynostosis-intracranial calcifications syndrome is a form of syndromic craniosynostosis characterized by pancraniosynostosis, head circumference below the mid-parental head circumference, mild facial dysmorphism (prominent supraorbital ridges, mild proptosis and maxillary hypoplasia) and calcification of the basal ganglia. The disease is associated with a favorable neurological outcome, normal intelligence and is inherited in an autosomal recessive manner. |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
4 |
Celiac disease, epilepsy and cerebral calcification syndrome (CEC) is a rare disorder characterized by the combination of auto-immune intestinal disease, epileptic seizures and cerebral calcifications. |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
4 |
Congenital intrauterine infection-like syndrome is characterized by the presence of microcephaly and intracranial calcifications at birth accompanied by neurological delay, seizures and a clinical course similar to that seen in patients after intrauterine infection with Toxoplasma gondii, Rubella, Cytomegalovirus, Herpes simplex (so-called TORCH syndrome), or other agents, despite repeated tests revealing the absence of any known infectious agent. |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
2 |
Calcific tendinitis of right achilles tendon (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
4 |
Calcific tendinitis of left achilles tendon (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
4 |
Chondrocalcinosis of joint of right wrist (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of joint of left wrist (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of joint of right knee (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of joint of left knee (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Mammographic calcification of right breast |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
2 |
Mammographic calcification of left breast |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
2 |
Cerebral calcification |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
2 |
Cerebroretinal microangiopathy with calcifications and cysts |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
A rare systemic disease characterized by progressive hyalinosis involving capillaries, arterioles and small veins of the digestive tract, kidneys, and retina, associated with idiopathic cerebral calcifications, manifesting with severe diarrhea (with rectal bleeding and malabsorption), nephropathy (with renal failure and systemic hypertension), chorioretinal scarring, and subarachnoid hemorrhage. Poikiloderma and premature graying of the hair may be additionally observed. |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
5 |
A rare syndromic intellectual disability characterized by severe intellectual disability and calcification of the choroid plexus, associated with elevated cerebrospinal fluid protein concentration. Additional signs and symptoms include strabismus, increased deep tendon reflexes, and foot deformities, among others. There have been no further descriptions in the literature since 1993. |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
A rare multiple congenital anomalies/dysmorphic syndrome characterized by diffuse cartilage calcification, brachytelephalangism, peripheral pulmonary artery stenoses and facial dysmorphism. Vascular calcification has been reported in some cases. |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
5 |
Tropical calcific chronic pancreatitis (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
3 |
Familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis without severe ocular involvement (FHHN) is a form of familial primary hypomagnesemia, characterized by recurrent urinary tract infections, nephrolithiasis, bilateral nephrocalcinosis, renal magnesium (Mg) wasting, hypercalciuria and kidney failure. |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Calcific panniculitis (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
3 |
Intellectual disability-cataracts-calcified pinnae-myopathy syndrome is a rare, genetic intellectual disability syndrome characterized by macrocephaly, hypotonia, dysmorphic facial features (wide forehead, ptosis, downslanting palpebral fissures, enlarged and calcified external ears, large jaw), sparse body hair, tall stature, and intellectual disability. Hearing loss, insulin-resistant diabetes, and progressive distal muscle wasting (leading to joint contractures) have also been reported in adulthood. Rare manifestations include behavioral abnormalities (aggression and restlessness), hypothyroidism, cerebral calcification, ataxia, and peripheral neuropathy. |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
5 |
A rare genetic neurological disorder characterized by early-onset progressive leukoencephalopathy, severe developmental delay, early-onset or congenital deafness (only few cases reported without hearing loss), and visual impairment. All patients manifest calcifications in brain and spinal cord. Cognitive impairment, seizures, hypotonia, spastic tetraplegia or quadriplegia are observed in the majority of the patients. Variable features may include microcephaly and anemia. |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
5 |
Bonnemann-Meinecke-Reich syndrome is a syndrome of multiple congenital anomalies characterized by an encephalopathy which predominantly occurs in the first year of life and presenting as psychomotor delay. Additional features of the disease include moderate dysmorphia, craniosynostosis, dwarfism (due to growth hormone deficiency), intellectual disability, spasticity, ataxia, retinal degeneration, and adrenal and uterine hypoplasia. The disease has been described in only two families, with each family having two affected siblings. An autosomal recessive inheritance has been suggested. There have been no further descriptions in the literature since 1991. |
Associated morphology |
False |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
4 |
Chondrocalcinosis of right shoulder (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of left shoulder |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of right elbow |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of left elbow |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of right hand (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of left hand |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of right hip |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of left hip (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of right ankle (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of left ankle (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
1 |
Chondrocalcinosis of bilateral wrists (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
2 |
Chondrocalcinosis of bilateral wrists (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
3 |
Chondrocalcinosis of bilateral ankles (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
2 |
Chondrocalcinosis of bilateral ankles (disorder) |
Associated morphology |
True |
Deposition of calcium in normally non calcified tissue |
Inferred relationship |
Some |
3 |