18288009: von Willebrand factor (substance)

SNOMED CT Concept\Substance\...

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Hematologic agent (substance)\Blood derivative (substance)\Coagulation related substance (substance)\...

\Intrinsic coagulation pathway substance (substance)\von Willebrand factor (substance)

\Coagulation protein\von Willebrand factor (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Plasma protein (substance)\Coagulation protein\von Willebrand factor (substance)

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Plasma protein (substance)\Coagulation protein\von Willebrand factor (substance)

\Biological substance\Protein and/or protein derivative\Protein\Plasma protein (substance)\Coagulation protein\von Willebrand factor (substance)
\Biological substance\Blood derivative (substance)\Coagulation related substance (substance)\Intrinsic coagulation pathway substance (substance)\von Willebrand factor (substance)
\Biological substance\Blood derivative (substance)\Coagulation related substance (substance)\Coagulation protein\von Willebrand factor (substance)
\Biological substance\Blood material\Blood component\Plasma protein (substance)\Coagulation protein\von Willebrand factor (substance)
\Biological substance\Hemostasis related substance\Coagulation related substance (substance)\Intrinsic coagulation pathway substance (substance)\von Willebrand factor (substance)
\Biological substance\Hemostasis related substance\Coagulation related substance (substance)\Coagulation protein\von Willebrand factor (substance)
\Biological substance\Polypeptide\Protein\Plasma protein (substance)\Coagulation protein\von Willebrand factor (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
von Willebrand factor (substance)	Is a	Intrinsic coagulation pathway substance (substance)	true	Inferred relationship	Some
von Willebrand factor (substance)	Is a	Coagulation protein	true	Inferred relationship	Some
von Willebrand factor (substance)	Is a	Procoagulant	false	Inferred relationship	Some
von Willebrand factor (substance)	Is a	Hematologic agent (substance)	false	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
von Willebrand factor ristocetin cofactor	Is a	False	von Willebrand factor (substance)	Inferred relationship	Some
von Willebrand factor multimer	Is a	True	von Willebrand factor (substance)	Inferred relationship	Some
von Willebrand factor antigen	Is a	True	von Willebrand factor (substance)	Inferred relationship	Some
von Willebrand factor antigen	Direct substance	False	von Willebrand factor (substance)	Inferred relationship	Some
Factor VIII R: R Co assay	Has measured component (attribute)	False	von Willebrand factor (substance)	Inferred relationship	Some
Factor VIII R: WF assay	Has measured component (attribute)	False	von Willebrand factor (substance)	Inferred relationship	Some
von Willebrand factor multimer assay	Has measured component (attribute)	False	von Willebrand factor (substance)	Inferred relationship	Some
Factor VIII R: Ag assay	Has measured component (attribute)	False	von Willebrand factor (substance)	Inferred relationship	Some
Factor VIII R: R Co assay	Component	False	von Willebrand factor (substance)	Inferred relationship	Some	2
Factor VIII R: WF assay	Component	True	von Willebrand factor (substance)	Inferred relationship	Some	1
von Willebrand factor multimer assay	Component	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Factor VIII R: Ag assay	Component	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Von Willebrand factor products adverse reaction	Causative agent (attribute)	False	von Willebrand factor (substance)	Inferred relationship	Some
von Willebrand factor products allergy	Causative agent (attribute)	False	von Willebrand factor (substance)	Inferred relationship	Some
Product containing von Willebrand factor (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Ristocetin 1.5 umol test (procedure)	Component	False	von Willebrand factor (substance)	Inferred relationship	Some	2
Ristocetin 0.5 umol test (procedure)	Component	False	von Willebrand factor (substance)	Inferred relationship	Some	2
Factor VIII fraction products adverse reaction	Causative agent (attribute)	False	von Willebrand factor (substance)	Inferred relationship	Some
Factor VIII by-passing fraction products adverse reaction	Causative agent (attribute)	False	von Willebrand factor (substance)	Inferred relationship	Some
Coagulation factor VIII- and von Willebrand factor-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor (substance)	Inferred relationship	Some
facteur VIII 500 U.I./facteur von Willebrand 1 100 U.I.,fiole de poudre et solvant pour solution injectable	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor (substance)	Inferred relationship	Some
facteur VIII 1 000 U.I./facteur von Willebrand 2 200 U.I., fiole de poudre et solvant pour solution injectable	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor (substance)	Inferred relationship	Some
Factor VIII 500iu/von Willebrand factor 1250iu powder for injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor (substance)	Inferred relationship	Some
Factor VIII 1000iu/von Willebrand factor 2500iu powder for injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor (substance)	Inferred relationship	Some
Coagulation factor VIII	Is a	False	von Willebrand factor (substance)	Inferred relationship	Some
von Willebrand factor products allergy	Causative agent (attribute)	False	von Willebrand factor (substance)	Inferred relationship	Some	1
facteur VIII 500 U.I./facteur von Willebrand 1 100 U.I.,fiole de poudre et solvant pour solution injectable	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor (substance)	Inferred relationship	Some
facteur VIII 1 000 U.I./facteur von Willebrand 2 200 U.I., fiole de poudre et solvant pour solution injectable	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor (substance)	Inferred relationship	Some
Factor VIII 500iu/von Willebrand factor 1250iu powder for injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor (substance)	Inferred relationship	Some
Factor VIII 1000iu/von Willebrand factor 2500iu powder for injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor (substance)	Inferred relationship	Some
Factor VIII by-passing fraction products adverse reaction	Causative agent (attribute)	False	von Willebrand factor (substance)	Inferred relationship	Some
Factor VIII fraction products adverse reaction	Causative agent (attribute)	False	von Willebrand factor (substance)	Inferred relationship	Some
Coagulation factor VIII- and von Willebrand factor-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Factor VIII 500iu/von Willebrand factor 1100iu powder for conventional release solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor (substance)	Inferred relationship	Some
Factor VIII 1000iu/von Willebrand factor 2200iu powder for conventional release solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor (substance)	Inferred relationship	Some
Von Willebrand factor adverse reaction	Causative agent (attribute)	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Coagulation factor VIII and von Willebrand factor only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Product containing only von Willebrand factor (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Product containing von Willebrand factor in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Coagulation factor VIII and von Willebrand factor only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Product containing only von Willebrand factor in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Coagulation factor VIII 1000 unit and von Willebrand factor 2500 unit powder for solution for injection vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Coagulation factor VIII 1000 unit and von Willebrand factor 2500 unit powder for solution for injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Coagulation factor VIII 500 unit and von Willebrand factor 1250 unit powder for solution for injection vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Coagulation factor VIII 500 unit and von Willebrand factor 1250 unit powder for solution for injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Coagulation factor VIII- and von Willebrand factor-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Ristocetin 1.5 umol test (procedure)	Component	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Ristocetin 0.5 umol test (procedure)	Component	True	von Willebrand factor (substance)	Inferred relationship	Some	1
Factor VIII R: R Co assay	Component	True	von Willebrand factor (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
30884011	von Willebrand factor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
30885012	Factor VIII vWF	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
745687012	von Willebrand factor (substance)	en	Fully specified name	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
1222088017	vWF- von Willebrand factor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
2668756016	von Willebrand factor ristocetin cofactor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
17291000188114	facteur de Willebrand	fr	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module