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21483005: Structure of central nervous system (body structure)


Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module
36053015 Central nervous system en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
481035013 Central nervous system structure en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
2638268018 Structure of central nervous system (body structure) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core
2642337010 Structure of central nervous system en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
278861000077111 structure du système nerveux central fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module
959871000172115 systema nervosum centrale fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module
1002691000172114 système nerveux central fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module


2606 descendants. Search Descendants:

Expanded Value Set


Outbound Relationships Type Target Active Characteristic Refinability Group Values
Structure of central nervous system (body structure) Is a Entire subdivision of nervous system (body structure) false Inferred relationship Some
Structure of central nervous system (body structure) partie de Entire nervous system false Additional relationship Some
Structure of central nervous system (body structure) Is a Structure of nervous system (body structure) false Inferred relationship Some
Structure of central nervous system (body structure) Is a Structure of subdivision of nervous system (body structure) true Inferred relationship Some

Inbound Relationships Type Active Source Characteristic Refinability Group
Mixed germ cell neoplasm of central nervous system Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Quantitative electroencephalogram (procedure) Procedure site - Direct (attribute) True Structure of central nervous system (body structure) Inferred relationship Some 1
Intracranial hypotension due to cerebrospinal fluid fistula Finding site True Structure of central nervous system (body structure) Inferred relationship Some 2
Nongerminomatous germ cell tumor of central nervous system (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Fetal malformation of central nervous system Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Spontaneous intracranial hypotension (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
A very rare and severe type of NAGA deficiency characterized by infantile neuroaxonal dystrophy. Finding site False Structure of central nervous system (body structure) Inferred relationship Some 2
Alpha-N-acetylgalactosaminidase deficiency type 2 Finding site False Structure of central nervous system (body structure) Inferred relationship Some 2
Alpha-N-acetylgalactosaminidase deficiency type 3 (disorder) Finding site False Structure of central nervous system (body structure) Inferred relationship Some 2
Implantable analgesic spinal cord electrical stimulation system pulse generator This attribute represents the site where the device is intended to reside in or on the body. True Structure of central nervous system (body structure) Inferred relationship Some
Cockayne syndrome is a rare autosomal recessive disease, manifestations may include short stature, progeria, photosensitivity, and learning delay, failure to thrive in the newborn, microcephaly and neurological developmental delay. Type 3 Cockayne syndrome, is the mildest type. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Cockayne syndrome is a rare autosomal recessive disease, manifestations may include short stature, progeria, photosensitivity, and learning delay, failure to thrive in the newborn, microcephaly, neurological developmental delay. Type 1 Cockayne syndrome, also 'classic' or 'moderate' usually presents in early childhood. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Cockayne syndrome is a rare autosomal recessive disease, manifestations may include short stature, progeria, photosensitivity, and learning delay, failure to thrive in the newborn, microcephaly, neurological developmental delay. Type 2 Cockayne syndrome, also known as 'severe' or 'early onset' usually presents in at or soon after birth. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Bilateral upper motor neurone lesion Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Lesion of left upper motor neuron (finding) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Lesion of right upper motor neuron Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Upper motor neurone lesion (finding) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Hemiparesis of left side of face (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 2
Hemiparesis of right side of face (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 2
Fetal spina bifida (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 3
Neonatal agitation Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Neonatal hypokinesia Finding site True Structure of central nervous system (body structure) Inferred relationship Some 3
Coma in the newborn Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Pure autonomic failure (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 4
Leukotriene C4 synthase deficiency is an extremely rare fatal neurometabolic developmental disorder characterized clinically by muscular hypotonia, psychomotor retardation, failure to thrive, and microcephaly. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 4
Parkinsonian syndrome with idiopathic orthostatic hypotension (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 5
A rare syndromic intellectual deficiency characterized by psychomotor delay, severe progressive spastic quadriplegia, microcephaly, and a Hallermann-Streiff-like phenotype including absence of eyebrows and eyelashes, glaucoma, and small, beaked nose. Structural central nervous system abnormalities (cervical spinal cyst, occipital cranium bifidum occulatum) were additional findings. There have been no further descriptions in the literature since 1974. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 6
Progressive cerebellar ataxia with hypogonadism Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Primary primitive neuroectodermal neoplasm of central nervous system (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Spastic paralysis due to birth injury Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
A rare contiguous gene syndrome involving a partial deletion of chromosome 16 and characterized by early-onset and severe polycystic kidney disease with various manifestations of tuberous sclerosis (multiple angiomyolipomas, lymphangioleiomyomatosis and periventricular calcifications of the central nervous system). Finding site True Structure of central nervous system (body structure) Inferred relationship Some 3
Fibrous skin tumor of tuberous sclerosis Finding site True Structure of central nervous system (body structure) Inferred relationship Some 5
Tuberous sclerosis syndrome Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Pulmonary tuberous sclerosis (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 7
Anaplastic oligodendroglioma of central nervous system (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Anaplastic ependymoma of central nervous system Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Anaplastic oligoastrocytoma of central nervous system (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
An extremely rare slow-growing glial neoplasm of the central nervous system, usually arising in a superficial location in the cerebrum, affecting all ages and both sexes, and characterized by intractable seizures and headaches, with most cases being cured by surgical incision alone and therefore having a good prognosis. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Anaplastic ganglioglioma of central nervous system Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Cerebrospinal fluid shunt port/reservoir This attribute represents the site where the device is intended to reside in or on the body. True Structure of central nervous system (body structure) Inferred relationship Some
Germinoma of central nervous system Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Cerebrospinal fluid shunt catheter plug This attribute represents the site where the device is intended to reside in or on the body. True Structure of central nervous system (body structure) Inferred relationship Some
Lumbar or thoracic cerebrospinal fluid shunt subcutaneous anchor This attribute represents the site where the device is intended to reside in or on the body. True Structure of central nervous system (body structure) Inferred relationship Some
Gliosarcoma of central nervous system Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Giant cell glioblastoma of central nervous system Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Gemistocytic astrocytoma of central nervous system (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Fibrillary astrocytoma of central nervous system Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Astroblastoma of central nervous system Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
HSD10 disease is a rare, life-threatening neurometabolic disease characterized by a progressive neurodegenerative course, epilepsy, retinopathy and progressive cardiomyopathy. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 2
Central nervous system deficit Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Parasitic infection of central nervous system Finding site False Structure of central nervous system (body structure) Inferred relationship Some 1
TBCK-related intellectual disability syndrome is a rare, genetic, syndromic intellectual disability characterized by usually profound intellectual disability with absent speech, severe infantile hypotonia with decreased or absent reflexes, markedly slow motor development (with no progress beyond the ability to sit independently), early-onset epilepsy, strabismus and post-natal onset of progressive brain atrophy (including loss of brain volume, ex vacuo ventriculomegaly, dysgenesis of corpus callosum, white matter abnormalities ranging from non-specific changes to leukodystrophy). Swallowing difficulties, respiratory insufficiency, osteoporosis and variable craniofacial dysmorphisms (including plagio/brachycephaly, bitemporal narrowing, high-arched eyebrows, high nasal bridge, anteverted nares, high palate, tented upper lip) may constitute additional clinical features. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
A rare genetic multiple congenital anomalies/dysmorphic syndrome characterized by global developmental delay, intellectual disability, hypotonia, seizures, and autism spectrum disorder. Variable associated features include ophthalmologic anomalies, congenital heart defects, genitourinary defects, and craniofacial dysmorphism (including frontal bossing, epicanthal folds, low-set, posteriorly rotated ears, anteverted nares, and micrognathia). Brain imaging may show thinning of the corpus callosum, white matter abnormalities, ventriculomegaly, and a small cerebellar vermis. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
A rare genetic multiple congenital anomalies/dysmorphic syndrome characterized by global developmental delay and intellectual disability, infantile hypotonia, microcephaly, movement disorder, and impaired balance. More variable manifestations are hearing loss, cortical visual impairment, abnormalities of fingers and/or toes, congenital cardiac anomalies, kyphoscoliosis, dysmorphic facial features, abnormal sleep pattern, and seizures, among others. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 2
Non-Hodgkin lymphoma of central nervous system metastatic to lymph node of lower limb Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Non-Hodgkin lymphoma of central nervous system metastatic to lymph node of upper limb (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Intraocular non-Hodgkin malignant lymphoma (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Granuloma of central nervous system caused by Schistosoma (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Pediatric multiple sclerosis (MS) is a rare multiple sclerosis variant characterized by the onset of multiple sclerosis (i.e. one or multiple episodes of clinical CNS symptoms consistent with acquired CNS demyelination, with radiologically proven dissemination of inflammatory lesions in space and time, following exclusion of other disorders) before the age of 18 years old. Pediatric MS patients present a predominantly relapsing-remitting course with first attack usually consisting of optic neuritis, transverse myelitis, acute disseminated encephalomyelitis and monofocal or polyfocal neurological deficits. A high burden of T2-hyperintense lesions on initial MRI, primarily of the supratentorial region and/or of the cervical spinal cord, has been reported. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Pediatric multiple sclerosis (MS) is a rare multiple sclerosis variant characterized by the onset of multiple sclerosis (i.e. one or multiple episodes of clinical CNS symptoms consistent with acquired CNS demyelination, with radiologically proven dissemination of inflammatory lesions in space and time, following exclusion of other disorders) before the age of 18 years old. Pediatric MS patients present a predominantly relapsing-remitting course with first attack usually consisting of optic neuritis, transverse myelitis, acute disseminated encephalomyelitis and monofocal or polyfocal neurological deficits. A high burden of T2-hyperintense lesions on initial MRI, primarily of the supratentorial region and/or of the cervical spinal cord, has been reported. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 2
A rare genetic disease characterized by onset of neurological deterioration in the first two years of life, progressing to severe intellectual disability, profound ataxia, mild dyskinesia, axial hypotonia, camptocormia, and oculomotor apraxia. Some patients also develop nephropathy with features of tubulointerstitial nephritis, hypertension, and a tendency for hyperkalemia. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Mitochondrial respiratory chain complex I structural subunit gene defect Finding site True Structure of central nervous system (body structure) Inferred relationship Some 3
Mitochondrial respiratory chain complex I assembly gene defect Finding site True Structure of central nervous system (body structure) Inferred relationship Some 3
Yolk sac tumour of central nervous system Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
A rare primary germ cell tumor of central nervous system characterized by a lesion typically in the region of the pineal gland and the suprasellar compartment, composed of cytotrophoblastic elements and multinucleated syncytiotrophoblastic giant cells. Ectatic stromal vascular channels, blood lakes, and extensive hemorrhagic necrosis are the rule. The tumor usually arises in the second decade of life and predominantly in males. Clinical presentation depends on location and size and includes signs of increased intracranial pressure, visual disturbances, and endocrine abnormalities. Prognosis is generally poor. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
A rare primary germ cell tumor of central nervous system characterized by a lesion typically in the region of the pineal gland and the suprasellar compartment, composed of cytotrophoblastic elements and multinucleated syncytiotrophoblastic giant cells. Ectatic stromal vascular channels, blood lakes, and extensive hemorrhagic necrosis are the rule. The tumor usually arises in the second decade of life and predominantly in males. Clinical presentation depends on location and size and includes signs of increased intracranial pressure, visual disturbances, and endocrine abnormalities. Prognosis is generally poor. Finding site False Structure of central nervous system (body structure) Inferred relationship Some 2
A rare autosomal ichthyosis syndrome with prominent neurologic signs characterized by the association of congenital ichthyosis with global developmental delay, intellectual disability, infantile-onset seizures, and spastic tetraplegia. Brain imaging may show delayed myelination and cerebral atrophy. Marked intrafamilial variability has been reported. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 5
A rare multiple congenital anomalies/dysmorphic syndrome characterized by global developmental delay or regression, variable congenital heart defects (such as patent ductus arteriosus, atrial or ventricular septal defects, and double outlet right ventricle, among others), and dysmorphic features (including ptosis, epicanthal folds, abnormally set/dysplastic ears, low hairline or excess nuchal skin, wide-spaced/inverted nipples, umbilical hernia or diastasis recti, and digital anomalies). Additional variable manifestations are hyper- or hypotonia, seizures, hearing loss, cortical blindness, and optic atrophy. Brain imaging may show cerebral and cerebellar atrophy and hydrocephalus. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Intracranial hypotension following ventricular shunting Finding site True Structure of central nervous system (body structure) Inferred relationship Some 4
A rare genetic syndromic intellectual disability characterized by infantile onset of global developmental delay and profound intellectual disability in association with a heterogeneous spectrum of manifestations, such as features of lower motor neuron disease, hypotonia, spasticity, contractures, seizures, respiratory insufficiency, and optic atrophy, among others. Dysmorphic craniofacial features include microcephaly, tall forehead, bitemporal narrowing, flat nasal bridge, low-set ears, and high-arched palate. Brain imaging may show cerebral and cerebellar atrophy, delayed myelination, and thin corpus callosum. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
A rare disorder of ornithine metabolism characterized by global developmental delay, alopecia, macrocephaly, and dysmorphic facial features (including high and broad forehead, hypertelorism, ptosis, blepharophimosis, downslanting palpebral fissures, deep-set eyes, large ears, and retrognathia or high arched palate). Additional reported manifestations are sensorineural hearing loss, spasticity, hypotonia, hypoplastic nails, cryptorchidism, and clinodactyly, among others. Brain imaging may show white matter abnormalities, periventricular cysts, enlarged lateral ventricles, or prominent perivascular spaces. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 4
Myelin oligodendrocyte glycoprotein antibody-associated disease Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Myelin oligodendrocyte glycoprotein antibody-associated disease Finding site True Structure of central nervous system (body structure) Inferred relationship Some 2
Primary oculocerebral lymphoma is a rare, primary, organ-specific, extranodal non-Hodgkin's lymphoma (typically diffuse large B-cell lymphoma), simultaneously affecting the intraocular compartments (retina, vitreous, optic nerve, uvea and others) and the central nervous system (commonly the cerebellum, spinal cord or pia mater). The presenting symptoms vary depending on the localization of the tumor and may include vitreous floaters or blurred vision, raised intracranial pressure (headache, vomiting, papilledema) and/or focal neurological deficits. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Metastatic neuroblastoma to central nervous system (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
A rare genetic disease characterized by juvenile-onset insulin-dependent diabetes mellitus associated with central and peripheral nervous system abnormalities with variable onset between infancy and adolescence. Neurological manifestations include combined cerebellar and afferent ataxia, sensorineural hearing loss, pyramidal tract signs, and demyelinating sensorimotor peripheral neuropathy. Hypothyroidism has been reported in some patients. Brain imaging may show generalized cerebral atrophy. Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Obstetric anesthesia with central nervous system complications - delivered Finding site False Structure of central nervous system (body structure) Inferred relationship Some 3
Obstetric anesthesia with central nervous system complication - delivered with postnatal problem Finding site False Structure of central nervous system (body structure) Inferred relationship Some 3
anesthésie obstétricale avec complication du système nerveux central et problème prénatal Finding site False Structure of central nervous system (body structure) Inferred relationship Some 3
anesthésie obstétricale avec complication du système nerveux central et problème postnatal Finding site False Structure of central nervous system (body structure) Inferred relationship Some 3
Obstetric anaesthesia with central nervous system complication in childbirth Finding site True Structure of central nervous system (body structure) Inferred relationship Some 3
Amyotrophic lateral sclerosis with multiple system atrophy Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Demyelination of central nervous system due to Whipple disease (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Demyelination of central nervous system due to Lyme borreliosis (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Autonomic disorder due to multiple sclerosis Finding site True Structure of central nervous system (body structure) Inferred relationship Some 3
Autonomic disorder due to multiple sclerosis Finding site True Structure of central nervous system (body structure) Inferred relationship Some 4
Primary neuroblastoma of central nervous system Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Primary ganglioneuroblastoma of central nervous system Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Primary glioblastoma multiforme of central nervous system (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Primary malignant glioma of central nervous system (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Primary anaplastic oligoastrocytoma of central nervous system (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Primary anaplastic ganglioglioma of central nervous system (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Primary mixed germ cell neoplasm of central nervous system (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Chronic inflammatory demyelinating disease of peripheral nervous system and central nervous system (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Chronic inflammatory demyelinating disease of peripheral nervous system and central nervous system (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 2
Presence of regression of primary malignant neoplasm of central nervous system after neoadjuvant antineoplastic therapy (observable entity) This attribute specifies the location of the entity specified by the attribute "Inheres in". False Structure of central nervous system (body structure) Inferred relationship Some 8
Increased cerebrospinal fluid production due to choroid plexus carcinoma (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Increased cerebrospinal fluid production due to benign papilloma of choroid plexus (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Increased cerebrospinal fluid production due to hyperplasia of choroid plexus (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Intracranial hypotension due to cerebrospinal fluid otorrhea (disorder) Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1
Intracranial hypotension due to cerebrospinal fluid rhinorrhoea Finding site True Structure of central nervous system (body structure) Inferred relationship Some 1

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Reference Sets

Anatomy structure and entire association reference set (foundation metadata concept)

Anatomy structure and part association reference set (foundation metadata concept)

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