Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Injury of adrenal gland (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Congenital anomaly of adrenal gland |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
1 |
Adrenalectomy NEC |
Procedure site - Direct (attribute) |
False |
Adrenal structure |
Inferred relationship |
Some |
1 |
Specimen from adrenal gland obtained by partial adrenalectomy (specimen) |
Specimen source topography |
False |
Adrenal structure |
Inferred relationship |
Some |
1 |
Adrenal biopsy specimen (specimen) |
Specimen source topography |
False |
Adrenal structure |
Inferred relationship |
Some |
1 |
Computed tomography of adrenal gland with contrast (procedure) |
Procedure site - Direct (attribute) |
False |
Adrenal structure |
Inferred relationship |
Some |
1 |
Magnetic resonance imaging of adrenal gland with contrast (procedure) |
Procedure site - Direct (attribute) |
False |
Adrenal structure |
Inferred relationship |
Some |
1 |
Radionuclide imaging of adrenal gland using iodocholesterol (procedure) |
Procedure site - Direct (attribute) |
False |
Adrenal structure |
Inferred relationship |
Some |
1 |
Injury of adrenal gland with open wound into abdominal cavity (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
2 |
Malignant neoplasm of adrenal gland NOS |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
1 |
Radionuclide imaging of adrenal gland using iodocholesterol (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Biopsy of adrenal gland |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Magnetic resonance imaging of adrenal gland with contrast (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Adrenal neuroblastoma (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Computed tomography of adrenal gland with contrast (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Fine needle biopsy of adrenal gland |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Adrenal gland hematoma |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Specimen from adrenal gland obtained by fine needle aspiration biopsy |
Specimen source topography |
False |
Adrenal structure |
Inferred relationship |
Some |
1 |
Enlarged adrenal gland (disorder) |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
1 |
Manipulation of adrenal gland |
Procedure site - Direct (attribute) |
False |
Adrenal structure |
Inferred relationship |
Some |
1 |
Specimen from adrenal gland obtained by fine needle aspiration biopsy |
Specimen source topography |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Laparoscopic excision of adrenal gland by retroperitoneal approach (procedure) |
Procedure site - Direct (attribute) |
False |
Adrenal structure |
Inferred relationship |
Some |
1 |
Laparoscopic excision of adrenal gland by retroperitoneal approach (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Injury of adrenal gland without open wound into abdominal cavity |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
2 |
21-hydroxylase deficiency |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
|
Reimplantation of adrenal tissue (procedure) |
Procedure site |
False |
Adrenal structure |
Inferred relationship |
Some |
1 |
Ectopic adrenal gland (disorder) |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
2 |
Congenital abnormal fusion of adrenal glands |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
2 |
Congenital anomaly of adrenal gland |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
2 |
Congenital absence of adrenal gland |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
2 |
Accessory adrenal gland |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
2 |
Congenital abnormal shape of adrenal gland |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
2 |
Extracapsular adrenal tissue |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
2 |
Congenital malposition of adrenal gland |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
2 |
Congenital cyst of adrenal gland |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
3 |
Aplasia of adrenal gland |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Proopiomelanocortin deficiency causes severe obesity beginning at an early age. Affected individuals also have low levels of adrenocorticotropic hormone (ACTH) and tend to have red hair and pale skin. |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
3 |
Liddle syndrome |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
|
Adrenal incidentaloma (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Findings similar to those in primary aldosteronism such as hypertension, hypokalemia, metabolic alkalosis, and low plasma renin activity caused by chronic ingestion of licorice (the root of glycyrrhiza glabra) and/or licorice-like compounds (such as carbenoxolone), or triazole antifungals (posaconazole and itraconazole). Plasma aldosterone levels are low rather than elevated as in primary aldosteronism. |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
|
Pseudoprimary hyperaldosteronism (disorder) |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
|
Imaging guided percutaneous fine needle aspiration biopsy of adrenal gland |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
2 |
Imaging guided percutaneous fine needle aspiration biopsy of adrenal gland |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
3 |
Percutaneous radiofrequency ablation of lesion of adrenal gland (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Biopsy of adrenal gland using computed tomography guidance (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
2 |
Biopsy of adrenal gland using computed tomography guidance (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
3 |
Tuberculosis of adrenal glands |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
2 |
Primary unilateral adrenal hyperplasia (PUAH) is a surgically-correctable form of primary (hyper) aldosteronism characterized by renin suppression, unilateral aldosterone hypersecretion, and moderate to severe hypertension secondary to hyperplasia of the adrenal gland. |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Myelolipoma of adrenal gland (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
A rare adrenal Cushing syndrome characterized by bilateral benign adrenal macronodules (>1 cm) that potentially produce autonomously variable levels of cortisol excess. Although in most cases are ACTH-independent, non-suppressed ACTH levels have been described. |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Hemorrhage of adrenal gland due to birth trauma (disorder) |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
3 |
Hemorrhage of adrenal gland due to birth trauma (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
4 |
Percutaneous needle biopsy of adrenal gland using computed tomography guidance (procedure) |
Procedure site - Indirect (attribute) |
False |
Adrenal structure |
Inferred relationship |
Some |
2 |
Percutaneous needle biopsy of adrenal gland using computed tomography guidance (procedure) |
Procedure site - Direct (attribute) |
False |
Adrenal structure |
Inferred relationship |
Some |
3 |
SERKAL (SEx Reversion, Kidneys, Adrenal and Lung dysgenesis) syndrome is characterized by female to male sex reversal and developmental anomalies of the kidneys, adrenal glands and lungs. |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
7 |
Magnetic resonance imaging of adrenal gland without contrast (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Computed tomography of adrenal gland without contrast (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Biopsy of adrenal gland using ultrasonographic guidance (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
2 |
Biopsy of adrenal gland using ultrasonographic guidance (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
3 |
Multiple endocrine neoplasia, type 2b |
Finding site |
False |
Adrenal structure |
Inferred relationship |
Some |
3 |
Pseudoprimary hyperaldosteronism (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Open biopsy of adrenal gland (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Radionuclide scan of adrenal gland using iodine 123 meta-iodobenzylguanidine |
Procedure site - Direct (attribute) |
False |
Adrenal structure |
Inferred relationship |
Some |
1 |
Radionuclide imaging of adrenal gland using iobenguane (123-I) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Incision and exploration of adrenal gland |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Incision and exploration of adrenal gland |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
2 |
SERKAL (SEx Reversion, Kidneys, Adrenal and Lung dysgenesis) syndrome is characterized by female to male sex reversal and developmental anomalies of the kidneys, adrenal glands and lungs. |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Corticosteroid-binding globulin deficiency is a rare, genetic, adrenal disease characterized by diminished corticosteroid-binding capacity associated with normal or low plasma corticosteroid-binding globulin concentration and reduced total plasma cortisol levels. Patients typically present chronic pain, fatigue and hypo/hypertension. |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Late-onset isolated ACTH deficiency is a rare, acquired, pituitary hormone deficiency characterized by secondary adrenal insufficiency, with normal secretion of anterior pituitary hormones, except for ACTH. Patients present with weakness, fatigue, weight loss, anorexia, vomiting/nausea, hypoglycemia, and abnormally low serum ACTH and cortisol levels. Association with autoimmune disease such as Hashimoto's thyroiditis has been described. |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
2 |
Pseudoleprechaunism syndrome, Patterson type is a rare, genetic, adrenal disorder characterized by congenital bronzed hyperpigmentation, cutis laxa of the hands and feet, body disproportion (comprising large hands, feet, nose and ears), hirsutism and severe intellectual disability. Patients additionally present hyperadrenocorticism, cushingoid features, premature adrenarche and diabetes mellitus, as well as skeletal deformities (not present at birth and which progress with age). There have been no further descriptions in the literature since 1981. |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
3 |
A rare, genetic, developmental defect during embryogenesis disorder characterized by severe, early-onset, salt-wasting adrenal insufficiency and ambiguous/female external genitalia (irrespective of chromosomal sex) due to mutations in the CYP11A1 gene. Milder cases may present delayed onset of adrenal gland dysfunction and genitalia phenotype may range from normal male to female in individuals with 46,XY karyotype. Imaging studies reveal hypoplastic/absent adrenal glands and biochemical findings include low serum cortisol, mineralocorticoids, androgens, and sodium, with elevated potassium levels. |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
2 |
A rare, genetic, endocrine disease characterized by defect in conversion of cortisone to active cortisol, resulting in ACTH-mediated excessive androgen release from adrenal glands. Premature adrenarche is typical with precocious pseudopuberty, proportionate tall stature and accelerated bone maturation in males, and hirsutism, oligoamenorrhea, central obesity and infertility in females. Imaging studies may indicate adrenal hyperplasia. |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Adrenal tissue structure |
Is a |
True |
Adrenal structure |
Inferred relationship |
Some |
|
Generalized glucocorticoid resistance syndrome (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
A rare condition characterized by generalized, partial, target tissue resistance to glucocorticoids. The clinical spectrum of the condition is broad, ranging from asymptomatic to severe cases of hyperandrogenism, fatigue and/or mineralocorticoid excess. The molecular basis of glucocorticoid resistance has been ascribed to mutations in the GR gene. |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Hemorrhage of adrenal gland due to birth trauma (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Precocious puberty with adrenal hyperplasia |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
2 |
Adrenogenital disorder caused by drug (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Histologic type of primary malignant neoplasm of adrenal gland (observable entity) |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
False |
Adrenal structure |
Inferred relationship |
Some |
5 |
Testicular lesion of adrenogenital syndrome |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Histologic grade of primary malignant neoplasm of adrenal gland |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
False |
Adrenal structure |
Inferred relationship |
Some |
5 |
Anatomic location directly invaded by primary malignant neoplasm of adrenal gland |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
False |
Adrenal structure |
Inferred relationship |
Some |
6 |
Surgical margin involved by primary malignant neoplasm of adrenal gland in excised adrenal gland specimen |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
False |
Adrenal structure |
Inferred relationship |
Some |
7 |
Hypoadrenalism due to paracoccidioidomycosis (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Cushing syndrome due to bilateral adrenocortical hyperplasia |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Percutaneous needle biopsy of adrenal gland using computed tomography guidance (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Percutaneous needle biopsy of adrenal gland using computed tomography guidance (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
2 |
Abscess of adrenal gland (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Male sexual precocity with adrenal hyperplasia (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
3 |
Sclerosis of adrenal gland |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Edema of adrenal gland (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Fibrosis of adrenal gland |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Iatrogenic adrenogenital disorder |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Suppression of adrenal gland |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Percutaneous cryoablation of lesion of adrenal gland |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Degeneration of adrenal gland |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Hypertrophy of adrenal gland (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Laparoscopic excision of adrenal gland using robotic assistance (procedure) |
Procedure site - Direct (attribute) |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Inflammation of adrenal gland (disorder) |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
Idiopathic adrenogenital disorder |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |
A rare endocrine disease characterized by neonatal hypoglycemia, prolonged cholestatic jaundice, and seizures. Typical are low plasma ACTH and cortisol levels in the absence of structural pituitary defects, and sometimes low partial growth hormone deficiency is associated. |
Finding site |
True |
Adrenal structure |
Inferred relationship |
Some |
1 |