Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Very slow |
Is a |
True |
Slow |
Inferred relationship |
Some |
|
Baseline bradycardia |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
1 |
Reflex bradycardia |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
1 |
On examination - pulse rate - bradycardia |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
2 |
Bradycardia - baseline fetal heart rate (finding) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
1 |
Bradycardia |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
1 |
Bradycardia - baseline fetal heart rate (finding) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
1 |
On examination - pulse rate - bradycardia |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
2 |
Baseline bradycardia |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
Reflex bradycardia |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
Bradycardia |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
Vagal autonomic bradycardia of prematurity (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
Persistent sinus bradycardia (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
Sinus bradycardia |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
Fetal bradycardia |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
AV-junctional (nodal) bradycardia |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
Vagal autonomic bradycardia |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
Symptomatic sinus bradycardia (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
Supraventricular bradyarrhythmia |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
Bradyarrhythmia (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
Neonatal bradycardia (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
Severe sinus bradycardia |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
Tachycardia-bradycardia |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
Fetal heart baseline rate range 40 to 80 (finding) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
Fetal heart baseline rate range 80 to 100 (finding) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
Bradycardia - baseline fetal heart rate (finding) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
Sinus bradycardia caused by drug (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
3 |
Sinus bradycardia due to metabolic disease |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
5 |
Psychomotor retardation |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
Parkinsonism |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
A rare neurodegenerative disease usually presenting before the age of 30 and which is characterized by dystonia, L-dopa-responsive parkinsonism, pyramidal signs and rapid cognitive decline. |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
Bradykinesia (finding) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
2 |
Parkinsonian syndrome with idiopathic orthostatic hypotension (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
7 |
Syphilitic parkinsonism |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
Striatonigral degeneration |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
Postencephalitic parkinsonism |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
Juvenile Parkinson's disease |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
3 |
Secondary parkinsonism |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
Carbon monoxide-induced parkinsonism |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
Manganese-induced parkinsonism |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
Parkinsonism with calcification of basal ganglia |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
3 |
Vascular parkinsonism |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
3 |
Symptomatic parkinsonism |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
On - off phenomenon (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
Impaired psychomotor performance (finding) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
2 |
A rare neurodegenerative disease characterized by extrapyramidal symptoms (rigidity, tremor, bradykinesia) and dementia, typically beginning in the fifth or sixth decade of life and progressing to a vegetative state with pelvicrural flexion contractures within few years. Oculomotor signs, olfactory dysfunction, and autonomic disturbances may also be observed. Neuropathological hallmarks are frontotemporally accentuated cerebral atrophy, as well as neurofibrillary tangles and neuronal loss in a characteristic distribution in cortical and subcortical regions. The disease is endemic to the Pacific Island of Guam. |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
6 |
Parkinsonism caused by carbon disulfide (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
Parkinsonism caused by methanol |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
X-linked dystonia parkinsonism |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
Perry syndrome |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
Abrupt onset of dystonia with parkinsonism over a period of hours to days. |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
A rare, genetic, neurological disorder characterized by parkinsonian features (including resting or action tremor, cogwheel rigidity, hypomimia and bradykinesia) associated with variably penetrant spasticity, hyperactive deep tendon reflexes and Babinski sign. |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
5 |
A rare parkinsonian syndrome due to intoxication which develops in individuals surviving an acute cyanide intoxication episode or due to chronic exposure to small cyanide doses. It presents several weeks after acute exposure with progressive typical clinical features of parkinsonism including bradykinesia, rigidity, dystonia, hypomimia, hypokinetic dysarthria, postural instability and retropulsion but no resting or postural tremor. Brain MRI reveals bilateral lesions in the pallidum, posterior putamen, substantia nigra, subthalamic nucleus, temporal and occipital cortex, and cerebellum. |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
3 |
Dissociative neurological symptom disorder co-occurrent with parkinsonism (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
A rare neuronal ceroid lipofuscinosis disorder characterized by juvenile-onset of progressive spinocerebellar ataxia, bulbar syndrome (manifesting with dysarthria, dysphagia and dysphonia), pyramidal and extrapyramidal involvement (including myoclonus, amyotrophy, unsteady gait, akinesia, rigidity, dysarthric speech) and intellectual deterioration. Muscle biopsy displays autofluorescent bodies and lipofuscin deposits in brain and, occasionally the retina, upon postmortem. |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
7 |
Orthostatic hypotension co-occurrent and due to Parkinson's disease (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
5 |
Parkinsonism co-occurrent and due to acute infection (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
Parkinsonism due to human immunodeficiency virus infection (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
Parkinsonism following infection (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
Parkinsonism due to hereditary spastic paraplegia (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
Infantile dystonia-parkinsonism (IPD) is an extremely rare inherited neurological syndrome that presents in early infancy with hypokinetic parkinsonism and dystonia and that can be fatal. |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
Atypical Parkinsonism (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
3 |
Parkinsonism due to heredodegenerative disorder (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
Kufor-Rakeb syndrome (KRS) is a rare genetic neurodegenerative disorder characterized by juvenile parkinsonism, pyramidal degeneration (dystonia), supranuclear palsy, and cognitive impairment. |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
Infection causing parkinsonism (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
Sporadic Parkinson disease (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
3 |
Parkinsonism due to and following injury of head (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
5 |
Parkinsonism due to mass lesion of brain (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
Functional parkinsonism (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
A complex form of young-onset Parkinson disease that manifests with pyramidal signs, eye movement abnormalities, psychiatric manifestations (depression, anxiety, drug-induced psychosis, and impulse control disorders), intellectual disability, and other neurological symptoms (such as ataxia and epilepsy) along with classical parkinsonian symptoms. |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
3 |
An adult-onset movement disorder characterized by bradykinesia, dysarthria and muscle rigidity. |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
A rare, genetic, parkinsonian disorder characterized by an age of onset between 21-45 years, rigidity, painful cramps followed by tremor, bradykinesia, dystonia, gait complaints and falls, and other non-motor symptoms. A slow disease progression and a more pronounced response to dopaminergic therapy are also observed in most forms of this disease. |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
3 |
Parkinsonism with dementia of Guadeloupe is characterized by symmetrical bradykinesia, predominantly axial rigidity, postural instability with early falls and cognitive decline with prominent features of frontal lobe dysfunction. |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
A rare X-linked syndromic intellectual disability characterized by infantile-onset non-progressive intellectual deficit (with psychomotor developmental delay, cognitive impairment and macrocephaly) and early-onset parkinsonism (before 45 years of age), in male patients. |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
4 |
Hereditary late-onset Parkinson disease (LOPD) is a form of Parkinson disease (PD), characterized by an age of onset of more than 50 years, tremor at rest, gait complaints and falls, bradykinesia, rigidity and painful cramps. Patients usually present a low risk of developing non motor symptoms, dystonia, dyskinesia and levodopa-induced dyskinesia (LID). |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
3 |
Infantile bilateral striatal necrosis (IBSN) comprises several syndromes of bilateral symmetric spongy degeneration of the caudate nucleus, putamen and globus pallidus characterized by developmental regression, choreoathetosis and dystonia progressing to spastic quadriparesis. IBSN can be familial or sporadic. |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
Hemiparkinsonism-hemiatrophy syndrome is a rare parkinsonian disorder characterized by unilateral body atrophy and slowly progressive, ipsilateral, hemiparkinsonian signs (bradykinesia, rigidity, and tremor). Patients typically present with unilateral, action-induced dystonia, in upper or lower limbs, that progresses and becomes bilateral or with tremor which occurs predominantly at rest and progresses to hemiparkinsonism. Scoliosis, scapular winging, raised shoulders, brisk reflexes and extensor plantar responses are frequently associated. |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
Parkinsonian-pyramidal syndrome is a rare, genetic, neurological disorder characterized by the association of both parkinsonian (i.e. bradykinesia, rigidity and/or rest tremor) and pyramidal (i.e. increased reflexes, extensor plantar reflexes, pyramidal weakness or spasticity) manifestations, which vary according to the underlying associated disease (e.g. neurodegenerative disease, inborn errors of metabolism). |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
4 |
Sporadic infantile bilateral striatal necrosis |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
Autosomal recessive familial Parkinson disease |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
3 |
Progressive supranuclear palsy parkinsonism syndrome (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
6 |
Neuroleptic-induced parkinsonism |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
Parkinson's disease |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
MPTP-induced parkinsonism |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
Parkinsonism caused by drug |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
Psychosis co-occurrent and due to Parkinson's disease (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
Parkinsonism following Mycoplasma infection (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
Parkinsonism due to prion disease (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
3 |
Toxin-induced parkinsonism |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
Parkinsonism caused by pesticide (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
Familial infantile bilateral striatal necrosis is the familial form of infantile bilateral striatal necrosis, a syndrome of bilateral symmetric spongy degeneration of the caudate nucleus, putamen and globus pallidus characterized by developmental regression, choreoathetosis and dystonia progressing to spastic quadriparesis. |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
Asymptomatic bradycardia |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
A rare neurologic disease characterized by multifaceted motor system dysfunctions and cognitive defects such as asymmetric rigidity, bradykinesia, limb apraxia, and visuospatial dysfunction. |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
3 |
Drug-induced bradycardia (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
1 |
A rare clinical situation occurring in the context of Parkinson disease characterized by return or worsening of symptoms (including motor and/or non-motor symptoms) under antiparkinsonian therapy. Types of off-periods are Morning Off (experienced before the first dose of the day), Delayed On (occurring more frequently after the first dose of the day or after meals), Wearing Off (end-of-dose deterioration), Sudden Off (sudden transition from on to off), and Dose Failure. |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
Amyotrophic lateral sclerosis with parkinsonism |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
3 |
Amyotrophic lateral sclerosis, parkinsonism, dementia complex of Kii Peninsula (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
5 |
Amyotrophic lateral sclerosis, parkinsonism, dementia complex of West New Guinea (disorder) |
Has interpretation |
False |
Slow |
Inferred relationship |
Some |
5 |
Parkinsonism caused by dopamine receptor antagonist (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
Parkinsonism caused by dopamine depleting agent (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |
Psychomotor retardation due to and following embolic cerebrovascular accident (disorder) |
Has interpretation |
True |
Slow |
Inferred relationship |
Some |
2 |