277466009: Lymphoproliferative disorder (disorder)

SNOMED CT Concept\Clinical finding (finding)\Disease\Disorder of hematopoietic cell proliferation (disorder)\Lymphoproliferative disorder

Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Lymphoproliferative disorder	Is a	Malignant white blood cell disorder	false	Inferred relationship	Some
Lymphoproliferative disorder	Pathological process	Neoplastic process	false	Inferred relationship	Some
Lymphoproliferative disorder	Finding site	Lymphoid system consists of lymph nodes, lymphatic vessels and organs that contain lymphoid tissue, e.g. thymus, spleen.	false	Inferred relationship	Some
Lymphoproliferative disorder	Associated morphology	néoplasie maligne (morphologie)	false	Inferred relationship	Some
Lymphoproliferative disorder	Finding site	Hematopoietic system structure	false	Inferred relationship	Some
Lymphoproliferative disorder	Pathological process	Malignant neoplastic process	false	Inferred relationship	Some
Lymphoproliferative disorder	Finding site	Leukocyte	false	Inferred relationship	Some
Lymphoproliferative disorder	Is a	White blood cell disorder	false	Inferred relationship	Some
Lymphoproliferative disorder	Is a	Disorder of lymphoid system (disorder)	false	Inferred relationship	Some
Lymphoproliferative disorder	Finding site	Lymphocytic tissue structure	false	Inferred relationship	Some	1
Lymphoproliferative disorder	Associated morphology	Proliferation	false	Inferred relationship	Some	1
Lymphoproliferative disorder	Finding site	Hematopoietic system structure	false	Inferred relationship	Some
Lymphoproliferative disorder	Associated morphology	White blood cell abnormality	false	Inferred relationship	Some
Lymphoproliferative disorder	Is a	Disorder of hematopoietic cell proliferation (disorder)	true	Inferred relationship	Some
Lymphoproliferative disorder	Associated morphology	Lymphoproliferative disorder (morphologic abnormality)	true	Inferred relationship	Some	1

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Lymphoproliferative disorder following transplantation	Is a	False	Lymphoproliferative disorder	Inferred relationship	Some
Plasma cell disorder	Is a	False	Lymphoproliferative disorder	Inferred relationship	Some
Atypical lymphoproliferative disorder	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
Acute lymphoid leukemia	Is a	False	Lymphoproliferative disorder	Inferred relationship	Some
Chronic lymphoid leukemia, disease	Is a	False	Lymphoproliferative disorder	Inferred relationship	Some
Multiple myeloma and immunoproliferative disease	Is a	False	Lymphoproliferative disorder	Inferred relationship	Some
Lymphoreticular tumour	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
Immunoproliferative disorder	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
Hemolytic anemia associated with lymphoproliferative disorder	Associated with	False	Lymphoproliferative disorder	Inferred relationship	Some
X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
Lymphoproliferative disorder after transplantation of bone marrow (disorder)	Is a	False	Lymphoproliferative disorder	Inferred relationship	Some
Dianzani autoimmune lymphoproliferative disease (DALD) is a very rare disorder characterized by autoimmunity, lymphadenopathy and/or splenomegaly.	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
Natural killer (NK)-cell enteropathy is a benign NK-cell lymphoproliferative disease characterized by minor abdominal symptoms (abdominal pain, diverticulosis, constipation and reflux) due to NK cell-derived lesions in the mucosal layer of the gastrointestinal tract and often mistaken for NK or T-cell lymphoma.	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
RAS-associated autoimmune leukoproliferative disease (RALD) is a rare genetic disorder characterized by monocytosis, autoimmune cytopenias, lymphoproliferation, hepatosplenomegaly, and hypergammaglobulinemia.	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
Chronic cold agglutinin disease associated with B-cell neoplasm	Due to	True	Lymphoproliferative disorder	Inferred relationship	Some	9
Secondary autoimmune hemolytic anemia co-occurrent and due to lymphoproliferative disorder	Due to	True	Lymphoproliferative disorder	Inferred relationship	Some	2
Secondary autoimmune hemolytic anemia co-occurrent and due to lymphoproliferative disorder	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
Persistent polyclonal B-cell lymphocytosis (PPBL) is a rare, generally benign, lymphoproliferative hematological disease characterized by chronic, stable, persistent, polyclonal lymphocytosis of memory B-cell origin, the presence of binucleated lymphocytes in the peripheral blood, and a polyclonal increase in serum immunoglobulin M (IgM). Patients are most frequently asymptomatic or may present with mild splenomegaly.	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
Acquired angioedema due to activation of the classical complement pathway related to an underlying lymphoreticular disorder particularly lymphoma or monoclonal gammopathy of unknown significance (MGUS)	Due to	True	Lymphoproliferative disorder	Inferred relationship	Some	2
Acquired angioedema due to activation of the classical complement pathway related to an underlying lymphoreticular disorder particularly lymphoma or monoclonal gammopathy of unknown significance (MGUS)	Is a	False	Lymphoproliferative disorder	Inferred relationship	Some
Methotrexate-associated lymphoproliferative disorders are rare immunodeficiency-associated lymphoproliferative diseases characterized by lymphoid proliferation or lymphomas (large B-cell lymphoma, T-cell lymphoma, Hodgkin lymphoma, reactive lymphadenitis and a polymorphic post-transplant lymphoproliferative disorder) that develop in patients with different autoimmune diseases treated with methotrexate. Swelling is the predominant manifestation of the disease and regression after methotrexate withdrawal is observed in a significant proportion of patients.	Is a	False	Lymphoproliferative disorder	Inferred relationship	Some
A rare autosomal recessive primary immunodeficiency characterized by Epstein-Barr virus (EBV)-triggered lymphoproliferative disorders such as malignant B-cell proliferation, Hodgkin lymphoma, B-cell lymphoma and EBV-driven hemophagocytic lymphohistiocytosis (HLH). Aplastic anemia and inflammatory disorders such as uveitis and oral ulcers are also observed.	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
Iatrogenic immunodeficiency-associated lymphoproliferative disorder (disorder)	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
Cutaneous CD30+ lymphoproliferative disorder	Is a	False	Lymphoproliferative disorder	Inferred relationship	Some
A very rare Epstein-Barr virus-associated lymphoproliferative disorder characterised by a chronic, recurrent, vesiculopapular rash, which subsequently ulcerates and scars, located mainly on sun-exposed areas and which is associated with systemic manifestations, such as fever, weight loss, asthenia, facial oedema, arthralgia, lymphadenopathy, hepatosplenomegaly and/or increased liver enzymes. Hypersensitivity to mosquito bites has been associated and an increased risk of developing systemic lymphoma has been reported.	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
Primary cutaneous CD30 antigen positive T-cell lymphoproliferative disorder (disorder)	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
Vasculitis due to lymphoproliferative disorder	Due to	True	Lymphoproliferative disorder	Inferred relationship	Some	2
Hydroa vacciniforme-like cutaneous T-cell lymphoma	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
Autoimmune lymphoproliferative syndrome	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
A rare immune dysregulation disease with immunodeficiency characterized by infantile or childhood onset of a variable phenotype including recurrent/persistent bacterial, fungal, and viral infections with involvement of the skin, lower respiratory tract, and gastrointestinal tract, eczema, allergies, and inflammatory bowel disease, among others. EBV-related smooth muscle tumors have also been reported. Immunophenotyping shows decreased Treg counts, as well as a deficient CD3/CD28 co-stimulation response in CD4+ and CD8+ T-cells.	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
A rare autosomal recessive primary immunodeficiency characterized by susceptibility to Epstein-Barr virus (EBV)-associated lymphoproliferative disorders such as malignant B-cell proliferation, Hodgkin lymphoma, B-cell lymphoma, lymphoid granulomatosis, hemophagocytic lymphohistiocytosis, and smooth muscle tumor. Patients present persistent symptoms of infectious mononucleosis including recurrent febrile episodes, lymphadenopathies, and hepatosplenomegaly, accompanied by high EBV viral load in the blood. Additional manifestations are autoimmune diseases like hemolytic anemia or renal disease.	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some
A rare autosomal recessive primary immunodeficiency characterized by susceptibility to Epstein-Barr virus (EBV)-related disorders (B-cell lymphoproliferative disorders including Hodgkin lymphoma) as well as dysgammaglobulinemia and recurrent infections. Patients can present with recurrent fever, lymphadenopathy, hepatosplenomegaly, Behçet-like stomatitis, pharyngitis, tonsillitis, adenitis, and viral encephalitis.	Is a	True	Lymphoproliferative disorder	Inferred relationship	Some

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Id	Description	Lang	Type	Status	Case?	Module
413994012	Lymphoproliferative disorder	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
670505016	Lymphoproliferative disorder (disorder)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1830181000195116	disturbo linfoproliferativo	it	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
40281000188116	syndrome lymphoprolifératif	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
130461000077112	trouble lymphoprolifératif	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module