278910002: Coagulation factor VIII (substance)

SNOMED CT Concept\Substance\...

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Hematologic agent (substance)\Blood derivative (substance)\Coagulation related substance (substance)\...

\Intrinsic coagulation pathway substance (substance)\Coagulation factor VIII

\Coagulation protein\Coagulation factor VIII

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Plasma protein (substance)\Coagulation protein\Coagulation factor VIII

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Plasma protein (substance)\Coagulation protein\Coagulation factor VIII

\Biological substance\Protein and/or protein derivative\Protein\Plasma protein (substance)\Coagulation protein\Coagulation factor VIII
\Biological substance\Blood derivative (substance)\Coagulation related substance (substance)\Intrinsic coagulation pathway substance (substance)\Coagulation factor VIII
\Biological substance\Blood derivative (substance)\Coagulation related substance (substance)\Coagulation protein\Coagulation factor VIII
\Biological substance\Blood material\Blood component\Plasma protein (substance)\Coagulation protein\Coagulation factor VIII
\Biological substance\Hemostasis related substance\Coagulation related substance (substance)\Intrinsic coagulation pathway substance (substance)\Coagulation factor VIII
\Biological substance\Hemostasis related substance\Coagulation related substance (substance)\Coagulation protein\Coagulation factor VIII
\Biological substance\Polypeptide\Protein\Plasma protein (substance)\Coagulation protein\Coagulation factor VIII

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Coagulation factor VIII	Is a	Intrinsic coagulation pathway substance (substance)	false	Inferred relationship	Some
Coagulation factor VIII	Is a	von Willebrand factor (substance)	false	Inferred relationship	Some
Coagulation factor VIII	Is a	Coagulation protein	true	Inferred relationship	Some
Coagulation factor VIII	Is a	Intrinsic coagulation pathway substance (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Coagulation factor VIIIa	Is a	True	Coagulation factor VIII	Inferred relationship	Some
Factor VIII 250iu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Factor VIII 500iu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Factor VIII 1000iu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Product containing high purity factor VIII	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
High purity factor VIII fraction 250iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
High purity factor VIII fraction 500iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
High purity factor VIII fraction 1000iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
High purity factor VIII fraction 350iu powder for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Factor VIII 250iu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Factor VIII 500iu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Factor VIII 1000iu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Product containing factor VIII fraction	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Coagulation factor VIII- and von Willebrand factor-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Coagulation factor VIII	Inferred relationship	Some	2
facteur VIII 500 U.I./facteur von Willebrand 1 100 U.I.,fiole de poudre et solvant pour solution injectable	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
facteur VIII 1 000 U.I./facteur von Willebrand 2 200 U.I., fiole de poudre et solvant pour solution injectable	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Deoxyribonucleic acid factor VIII	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Intermediate factor VIII	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Product containing porcine factor VIII (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Coagulation factor II- and coagulation factor IX- and coagulation factor VIIa- and coagulation factor VIII- and coagulation factor X-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Coagulation factor VIII	Inferred relationship	Some	1
Factor VIII by-passing fraction 500iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Factor VIII by-passing fraction 1000iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Intermediate factor VIII fraction 250iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Intermediate factor VIII fraction 500iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Porcine factor VIII 700iu powder for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Coagulation factor VIII-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Coagulation factor VIII	Inferred relationship	Some	1
Factor VIII 500iu/von Willebrand factor 1250iu powder for injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Factor VIII 1000iu/von Willebrand factor 2500iu powder for injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Octocog alfa (substance)	Is a	False	Coagulation factor VIII	Inferred relationship	Some
Porcine factor VIII (substance)	Is a	True	Coagulation factor VIII	Inferred relationship	Some
Factor VIII fraction products adverse reaction	Causative agent (attribute)	False	Coagulation factor VIII	Inferred relationship	Some
Factor VIII by-passing fraction products adverse reaction	Causative agent (attribute)	False	Coagulation factor VIII	Inferred relationship	Some
Factor VIII fraction products allergy	Causative agent (attribute)	False	Coagulation factor VIII	Inferred relationship	Some
Allergy to anti-inhibitor coagulant complex (finding)	Causative agent (attribute)	False	Coagulation factor VIII	Inferred relationship	Some
Antihaemophilic factor transfusion	Direct substance	False	Coagulation factor VIII	Inferred relationship	Some	1
Antihaemophilic factor transfusion	Direct substance	True	Coagulation factor VIII	Inferred relationship	Some	1
Moroctocog alfa (substance)	Is a	False	Coagulation factor VIII	Inferred relationship	Some
Allergy to anti-inhibitor coagulant complex (finding)	Causative agent (attribute)	False	Coagulation factor VIII	Inferred relationship	Some	1
Factor VIII fraction products allergy	Causative agent (attribute)	False	Coagulation factor VIII	Inferred relationship	Some	1
Simoctocog alfa (substance)	Is a	False	Coagulation factor VIII	Inferred relationship	Some
Efmoroctocog alfa (substance)	Is a	False	Coagulation factor VIII	Inferred relationship	Some
Turoctocog alfa (substance)	Is a	False	Coagulation factor VIII	Inferred relationship	Some
Lonoctocog alfa (substance)	Is a	False	Coagulation factor VIII	Inferred relationship	Some
Factor VIII 500iu/von Willebrand factor 1100iu powder for conventional release solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Factor VIII 1000iu/von Willebrand factor 2200iu powder for conventional release solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Coagulation factor VIII	Inferred relationship	Some
Factor VIII adverse reaction (disorder)	Causative agent (attribute)	True	Coagulation factor VIII	Inferred relationship	Some	1
Coagulation factor II and coagulation factor IX and coagulation factor VIIa and coagulation factor VIII and coagulation factor X only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Coagulation factor VIII	Inferred relationship	Some	1
Coagulation factor VIII only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Coagulation factor VIII	Inferred relationship	Some	1
Coagulation factor VIII and von Willebrand factor only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Coagulation factor VIII	Inferred relationship	Some	2
Susoctocog alfa (substance)	Is a	False	Coagulation factor VIII	Inferred relationship	Some
Coagulation factor VIII and von Willebrand factor only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Coagulation factor VIII	Inferred relationship	Some	2
Coagulation factor VIII 1000 unit and von Willebrand factor 2500 unit powder for solution for injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Coagulation factor VIII	Inferred relationship	Some	2
Coagulation factor VIII 1000 unit and von Willebrand factor 2500 unit powder for solution for injection vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Coagulation factor VIII	Inferred relationship	Some	2
Coagulation factor VIII 500 unit and von Willebrand factor 1250 unit powder for solution for injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Coagulation factor VIII	Inferred relationship	Some	2
Coagulation factor VIII 500 unit and von Willebrand factor 1250 unit powder for solution for injection vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Coagulation factor VIII	Inferred relationship	Some	2
Coagulation factor VIII- and von Willebrand factor-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Coagulation factor VIII	Inferred relationship	Some	2
Product containing precisely coagulation factor VIII 500 unit/1 vial powder for conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Coagulation factor VIII	Inferred relationship	Some	1
Product containing precisely coagulation factor VIII 500 unit/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Coagulation factor VIII	Inferred relationship	Some	1
Product containing precisely coagulation factor VIII 250 unit/1 vial powder for conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Coagulation factor VIII	Inferred relationship	Some	1
Product containing precisely coagulation factor VIII 250 unit/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Coagulation factor VIII	Inferred relationship	Some	1
Product containing precisely coagulation factor VIII 1000 unit/1 vial powder for conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Coagulation factor VIII	Inferred relationship	Some	1
Product containing precisely coagulation factor VIII 1000 unit/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Coagulation factor VIII	Inferred relationship	Some	1
Coagulation factor VIII only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Coagulation factor VIII	Inferred relationship	Some	1
Product containing coagulation factor VIII in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Coagulation factor VIII	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
415960013	Antihaemophilic factor	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
415961012	Antihaemophilic globulin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
415962017	Antihaemophilic factor A	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415963010	Coagulation factor VIII	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415964016	AHG	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
415965015	Factor VIII	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415966019	AHF	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
415967011	Platelet cofactor I	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415968018	Antihemophilic factor A	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415969014	Antihemophilic factor	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
415970010	Antihemophilic globulin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4042397014	Coagulation factor VIII (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
237041000195117	fattore VIII di coagulazione	it	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
6914461000241113	facteur VIII de coagulation	fr	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
236211000195110	Blutgerinnungsfaktor VIII	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module