Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
A rare, hereditary, immune deficiency with skin involvement characterised by early-onset cold urticaria after generalised exposure to cold air or evaporative cooling and not after contact with cold objects. Additional immunologic abnormalities are often present - antibody deficiency, recurrent infections, autoimmune disease and symptomatic allergic disease. |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Oral ulceration caused by cold burn |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Poikiloderma caused by cold injury |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Idiopathic cold urticaria |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Cold panniculitis (disorder) |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Neonatal cold panniculitis (disorder) |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Cold reflex urticaria |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Delayed cold sensitivity |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Cold urticaria with agglutinins |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Cold urticaria with cryoglobulins |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Urticaria caused by cold |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Erythrocyanosis |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Erythrocyanosis with nodules (disorder) |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
3 |
Erythrocyanosis with nodules (disorder) |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
6 |
Cold injury of peripheral nerve |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Immersion foot |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Newborn environmental hypothermia |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
2 |
Left trench foot |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Right immersion foot (disorder) |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
Occupational cold-induced dermatosis |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
1 |
A rare genetic autoinflammatory syndrome with skin involvement characterised by cold-induced urticarial rash without angioedema starting in infancy and systemic inflammation due to autosomal dominant mutations in the coagulation factor 12 (F-12) gene. In addition to cold-induced, non-pruritic urticarial rash, patients present with headache, mild to severe arthralgia, fatigue, subfebrile evening temperature, chills, and malaise. Systemic symptoms worsen during the cold season and over the years. |
Causative agent (attribute) |
True |
Low temperature |
Inferred relationship |
Some |
2 |