Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Craniosynostosis-intracranial calcifications syndrome is a form of syndromic craniosynostosis characterized by pancraniosynostosis, head circumference below the mid-parental head circumference, mild facial dysmorphism (prominent supraorbital ridges, mild proptosis and maxillary hypoplasia) and calcification of the basal ganglia. The disease is associated with a favorable neurological outcome, normal intelligence and is inherited in an autosomal recessive manner. |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Circumscribed atrophy of brain |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
A rare syndromic intellectual disability characterized by severe intellectual disability and calcification of the choroid plexus, associated with elevated cerebrospinal fluid protein concentration. Additional signs and symptoms include strabismus, increased deep tendon reflexes, and foot deformities, among others. There have been no further descriptions in the literature since 1993. |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Syringobulbia |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Lesion of brainstem |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Cortical dysplasia |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Myelocele with hydrocephalus (disorder) |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Mesial temporal lobe epilepsy with hippocampal sclerosis is a rare epilepsy syndrome defined by seizures originating in limbic areas of the mesial temporal lobe, particularly in the hippocampus, amygdala, and in the parahippocampal gyrus and its connections, and hippocampal sclerosis, usually unilateral or asymmetric. It is frequently associated with an initial precipitating event, such as febrile seizures, hypoxia, intracranial infection or head trauma, most often occurring in the first five years of life, followed by a latent period without seizures. Typical seizures consist of a characteristic aura that is frequently a rising epigastric sensation associated with emotional disturbances, illusions, and autonomic symptoms (widened pupils, palpitations), progressive impairment of consciousness, oro-alimentary automatisms (lip smacking, chewing, licking, tooth grinding), behavioral arrest, head deviation, dystonic postures, hand and verbal automatisms. Seizures are followed by postictal dysfunction. Initially, seizures are easily controlled with antiepileptic drugs, later they frequently become refractory and associated with progressive behavioral changes and memory deficits. |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Congenital porencephaly |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Hydromicrocephaly |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Cystic malformation of posterior fossa (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Arteriovenous fistula of great cerebral vein of Galen (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Septic thrombophlebitis of lateral sinus |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Thrombosis of inferior sagittal sinus |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Embolism lateral sinus |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Embolism transverse sinus |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Septic thrombophlebitis of great cerebral vein |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
thrombose du sinus transverse |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Cerebral venous thrombosis of great cerebral vein |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Thrombosis of lateral venous sinus |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Thrombophlebitis lateral venous sinus |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Nodular heterotopia |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Schizencephaly |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Dentate dysplasia |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Embolism of inferior sagittal sinus |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Embolism of lateral venous sinus |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Pituitary fibrosis |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Entrapment of inferior horn of lateral ventricle |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Closed fracture of vault of skull with cerebral laceration AND/OR contusion |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Closed fracture of base of skull with loss of consciousness |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Congenital brain damage |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Brain disorder resulting from a period of impaired oxygen delivery to the brain (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
A rare neurologic disease characterized by a rapid onset of seizures, an altered state of consciousness, neurologic decline, and variable degrees of hepatic dysfunction following a respiratory or gastrointestinal infection (e.g. mycoplasma, influenza virus) in a previously healthy child. Brain MRI of patients reveals bilateral, multiple, symmetrical lesions predominantly observed in thalami and brainstem, but also in periventricular white matter and cerebellum in some cases. |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Progressive polyneuropathy with bilateral striatal necrosis is a rare, genetic disorder of thiamine metabolism and transport characterized by the childhood-onset of recurrent episodes of flaccid paralysis and encephalopathy, associated with bilateral striatal necrosis and chronic progressive axonal polyneuropathy with proximal and distal muscle weakness, areflexia, contractures and foot deformities. |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Cerebrovascular accident |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Closed fracture of vault of skull with concussion |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Closed fracture of base of skull with concussion |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Laceration of brain |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Contusion of brain |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Injuries of brain and cranial nerves with injuries of nerves and spinal cord at neck level |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Traumatic brain injury of unknown intent |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Traumatic brain injury with loss of consciousness |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Crush injury of brain (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Multiple traumatic hemorrhages of brain tissue (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Radiation injury of brain caused by ionizing radiation following radiotherapy procedure |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Traumatic intraventricular hemorrhage (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Dementia pugilistica |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Necrosis of brain caused by ionizing radiation |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Acute necrotizing encephalitis |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Closed fracture of skull with contusion of cerebrum (disorder) |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Closed fracture of skull with cerebral laceration |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Familial acute necrotising encephalopathy or ADANE is a potentially fatal neurological disease characterised by neuropathological lesions principally involving the brainstem, thalamus and putamen. |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Ischemic encephalopathy (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Traumatic brain injury with no loss of consciousness |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Post-traumatic epilepsy |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Brain injury with open intracranial wound |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Cerebral haemorrhage due to birth injury |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Focal brain injury |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Cerebral trauma |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Brain injury without open intracranial wound |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Traumatic hemorrhage of cerebellum (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Diffuse brain injury |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
encéphalopathie causée par radiolésion |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Cerebral decompression injury |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
épilepsie non photosensible auto-induite |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Cerebral leucomalacia |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Hypoxic ischemic encephalopathy (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Diffuse injury of cerebrum (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Diffuse injury of cerebellum (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
A degenerative brain disease linked to a history of repetitive head impacts such as those experienced in contact and collision sports or combat military service. |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Hypoxic ischemic encephalopathy of newborn (disorder) |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
A rare genetic central nervous system malformation characterized by dysplasia of the superior cerebellum (especially the vermis), brainstem asymmetry, dysplasia of the basal ganglia, and cortical irregularities with asymmetric abnormalities in gyral size and orientation, as well as varying sulcal depth, but without lissencephaly, pachygyria, or polymicrogyria. Clinically, patients present global developmental delay with motor development usually being more affected that speech. Variable features are abnormal eye movements including oculomotor apraxia, strabismus, seizures, and behavioral problems. |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Silent white matter disease due to vascular disease |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Cerebellar hemangioblastomatosis |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Granuloma of cerebral hemispheric lobe (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Granuloma of brain caused by Schistosoma |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Granuloma of brain caused by Schistosoma mansoni (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Granuloma of brain caused by Schistosoma haematobium |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Granuloma of brain caused by Schistosoma japonicum (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Parasitic infection causing granuloma of cerebrum (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Pyogranulomatous meningoencephalomyelitis |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Cerebellar granuloma |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Brain injury which develops up to one month following the start of therapeutic cranial irradiation. |
Is a |
False |
Lesion of brain |
Inferred relationship |
Some |
|
Dystonia due to focal brain lesion |
Due to |
True |
Lesion of brain |
Inferred relationship |
Some |
2 |
Blast injury to brain (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Localized lesion of brain |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Focal cortical dysplasia with abnormal architectural distortion of cortical layer Blumcke type III (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Cyst of brain (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|
Congenital dysplasia of fronto-parietal cortex (disorder) |
Is a |
True |
Lesion of brain |
Inferred relationship |
Some |
|