33359002: Degeneration (morphologic abnormality)

Status: retired, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2020. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

55660014 Degeneration en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

55662018 Degenerative change en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

764753012 Degeneration (morphologic abnormality) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

12461000077110 dégénérescence fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
dégénérescence	Is a	Degenerative abnormality	false	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
A rare autosomal recessive cerebellar ataxia characterized by early onset of non- or slowly progressive cerebellar signs and symptoms including truncal and gait ataxia, dysarthria, dysmetria, dysdiadochokinesis, tremor, and nystagmus. Delayed psychomotor development and intellectual disability are variable. Additional reported features are spasticity, hypotonia, cataracts, and sensorineural hearing loss, among others. Brain imaging shows cerebellar atrophy.	Associated morphology	False	dégénérescence	Inferred relationship	Some	5
Olivopontocerebellar atrophy-deafness syndrome is characterized by infancy-onset olivopontocerebellar atrophy, sensorineural deafness and speech impairment. It has been described in less than 15 children. Most cases were sporadic, but autosomal recessive inheritance was suggested in three cases.	Associated morphology	False	dégénérescence	Inferred relationship	Some	4
Choroideremia co-occurrent with hypopituitarism	Associated morphology	False	dégénérescence	Inferred relationship	Some	4
Spinocerebellar ataxia type 28 (SCA28) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by juvenile onset, slowly progressive cerebellar ataxia due to Purkinje cell degeneration.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Spinocerebellar ataxia type 28 (SCA28) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by juvenile onset, slowly progressive cerebellar ataxia due to Purkinje cell degeneration.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
An autosomal dominant cerebellar ataxia type I that is characterized by very slowly progressive or non-progressive ataxia, dysarthria, oculomotor abnormalities and intellectual disability.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
An autosomal dominant cerebellar ataxia type I that is characterized by very slowly progressive or non-progressive ataxia, dysarthria, oculomotor abnormalities and intellectual disability.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
An autosomal dominant cerebellar ataxia type III that is characterized by the late onset of ataxia, dysarthria and horizontal gaze nystagmus, and that is occasionally accompanied by pyramidal signs, tremor, decreased vibration sense and hearing difficulties.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
An autosomal dominant cerebellar ataxia type III that is characterized by the late onset of ataxia, dysarthria and horizontal gaze nystagmus, and that is occasionally accompanied by pyramidal signs, tremor, decreased vibration sense and hearing difficulties.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
A very rare autosomal recessive, slowly progressive neurodegenerative disorder characterized by the triad of cerebellar ataxia (that generally manifests at adolescence or early adulthood), chorioretinal dystrophy, which may have a later onset (up to the fifth-sixth decade) leading to variable degrees of visual impairment, and hypogonadotropic hypogonadism (delayed puberty and lack of secondary sex characteristics). Ataxia-hypogonadism-choroidal dystrophy syndrome belongs to a clinical continuum of neurodegenerative disorders along with the clinically overlapping cerebellar ataxia-hypogonadism syndrome.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Spinocerebellar ataxia type 15/16 (SCA15/16) is a rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by cerebellar ataxia, tremor and cognitive impairment.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Spinocerebellar ataxia type 15/16 (SCA15/16) is a rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by cerebellar ataxia, tremor and cognitive impairment.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Wilson's disease	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Wilson's disease	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Wilson's disease	Associated morphology	False	dégénérescence	Inferred relationship	Some	4
Macrocephaly-spastic paraplegia-dysmorphism syndrome is a rare syndrome of multiple congenital anomalies characterized by macrocephaly (of post-natal onset) with large anterior fontanelle, progressive complex spastic paraplegia, dysmorphic facial features (broad and high forehead, deeply set eyes, short philtrum with thin upper lip, large mouth and prominent incisors), seizures, and intellectual deficit of varying severity. Inheritance appears to be autosomal recessive.	Associated morphology	False	dégénérescence	Inferred relationship	Some	5
Progressive non-fluent aphasia (PNFA) is a form of frontotemporal dementia, characterized by agrammatism, laborious speech, alexia, and agraphia, frequently accompanied by apraxia of speech (AOS). Language comprehension is relatively preserved.	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Logopenic progressive aphasia (lv-PPA) is a form of primary progressive aphasia, characterized by impaired single-word retrieval and naming and impaired repetition with spared single-word comprehension and object knowledge.	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Right temporal atrophy variant frontotemporal dementia (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Maternally inherited Leigh syndrome is a rare subtype of Leigh syndrome characterized clinically by encephalopathy, lactic acidosis, seizures, cardiomyopathy, respiratory disorders and developmental delay, with onset in infancy or early childhood, and resulting from maternally-inherited mutations in mitochondrial DNA.	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Altered behavior due to Pick's disease (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	5
A rare, genetic, neurological disorder characterized by the association of slowly progressive spinocerebellar degeneration and corneal dystrophy, manifesting with bilateral corneal opacities (which lead to severe visual impairment), mild intellectual disability, ataxia, gait disturbances, and tremor. Additional manifestations include facial dysmorphism (i.e. triangular face, ptosis, low-set, posteriorly angulated ears, and micrognathia), as well as mild upper motor neuron involvement with hypertonia, lower limb hyperreflexia and extensor plantar responses. There have been no further descriptions in the literature since 1985.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Behavioral variant of frontotemporal dementia (bv-FTD) is a form of frontotemporal dementia, characterized by progressive behavioral impairment and a decline in executive function with frontal lobe-predominant atrophy.	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Infantile bilateral striatal necrosis (IBSN) comprises several syndromes of bilateral symmetric spongy degeneration of the caudate nucleus, putamen and globus pallidus characterized by developmental regression, choreoathetosis and dystonia progressing to spastic quadriparesis. IBSN can be familial or sporadic.	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
A rare degenerative mitochondrial disease characterized by chronic metabolic acidosis, hypotonia, facial dysmorphism and delayed development.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Advanced collapse of scapholunate joint due to osteoarthritis (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Alzheimer's disease with delirium (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
arthrose de la hanche concomitante de et due à une dysplasie	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
A very rare subtype of autosomal dominant cerebellar ataxia type III (ADCA type III) characterised by late-onset and slowly progressive cerebellar signs (gait ataxia) and eye movement abnormalities.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
A very rare subtype of autosomal dominant cerebellar ataxia type III (ADCA type III) characterised by late-onset and slowly progressive cerebellar signs (gait ataxia) and eye movement abnormalities.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Spinocerebellar ataxia type 25 (SCA25) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by cerebellar ataxia and prominent sensory neuropathy.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Spinocerebellar ataxia type 25 (SCA25) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by cerebellar ataxia and prominent sensory neuropathy.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Spinocerebellar ataxia type 20 (SCA20) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by cerebellar dysarthria as the initial typical manifestation.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Spinocerebellar ataxia type 20 (SCA20) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by cerebellar dysarthria as the initial typical manifestation.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Spinocerebellar ataxia type 23 (SCA23) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by gait ataxia, dysarthria, slowed saccades, ocular dysmetria, Babinski sign and hyperreflexia.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Spinocerebellar ataxia type 23 (SCA23) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by gait ataxia, dysarthria, slowed saccades, ocular dysmetria, Babinski sign and hyperreflexia.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Spinocerebellar ataxia type 21 (SCA21) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by slowly progressive cerebellar ataxia, mild cognitive impairment, postural and/or resting tremor, bradykinesia, and rigidity.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Spinocerebellar ataxia type 21 (SCA21) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by slowly progressive cerebellar ataxia, mild cognitive impairment, postural and/or resting tremor, bradykinesia, and rigidity.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
An X-linked syndromic intellectual disability characterized by a few months of normal development, followed by progressive neurodegenerative course with gradual loss of vision, development of spastic tetraplegia, convulsions, microcephaly, failure to thrive, and early death.	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
An X-linked syndromic intellectual disability characterized by congenital ataxia and generalized hypotonia, global developmental delay with intellectual disability, myoclonic encephalopathy, progressive neurological deterioration, macular degeneration, and recurrent bronchopulmonary infections.	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
A rare autosomal recessive complex spastic paraplegia characterized by upper motor neuron involvement and peripheral neuropathy with an onset between childhood and early adulthood. Patients present with progressive spasticity, hyperreflexia, and distal upper and lower muscle wasting. Reduced cognitive functioning and cerebellar ataxia have also been reported. MR imaging may reveal cerebellar and/or spinal cord atrophy.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
A rare neurologic disease that is characterized by the early onset of cerebellar signs, eye movement abnormalities and pyramidal signs.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
A rare neurologic disease that is characterized by the early onset of cerebellar signs, eye movement abnormalities and pyramidal signs.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Spinocerebellar ataxia type 12 (SCA12) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by the presence of action tremor associated with relatively mild cerebellar ataxia. Associated pyramidal and extrapyramidal signs and dementia have been reported.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Spinocerebellar ataxia type 12 (SCA12) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by the presence of action tremor associated with relatively mild cerebellar ataxia. Associated pyramidal and extrapyramidal signs and dementia have been reported.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Spinocerebellar ataxia type 13 (SCA13) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by onset in childhood marked by delayed motor and cognitive development followed by mild progression of cerebellar ataxia.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Spinocerebellar ataxia type 13 (SCA13) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by onset in childhood marked by delayed motor and cognitive development followed by mild progression of cerebellar ataxia.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Spinocerebellar ataxia type 14 (SCA14) is a rare mild subtype of type I autosomal dominant cerebellar ataxia. It is characterized by slowly progressive ataxia, dysarthria and nystagmus.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Spinocerebellar ataxia type 14 (SCA14) is a rare mild subtype of type I autosomal dominant cerebellar ataxia. It is characterized by slowly progressive ataxia, dysarthria and nystagmus.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Spinocerebellar ataxia type 17 (SCA17) is a rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by a variable clinical picture which can include dementia, psychiatric disorders, parkinsonism, dystonia, chorea, spasticity, and epilepsy.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Spinocerebellar ataxia type 17 (SCA17) is a rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by a variable clinical picture which can include dementia, psychiatric disorders, parkinsonism, dystonia, chorea, spasticity, and epilepsy.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Spinocerebellar ataxia type 18 (SCA18) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by sensory neuropathy and cerebellar ataxia.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Spinocerebellar ataxia type 18 (SCA18) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by sensory neuropathy and cerebellar ataxia.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Spinocerebellar ataxia type 19 (SCA19) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by mild cerebellar ataxia, cognitive impairment, low scores on the Wisconsin Card Sorting Test measuring executive function, myoclonus, and postural tremor.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Spinocerebellar ataxia type 19 (SCA19) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by mild cerebellar ataxia, cognitive impairment, low scores on the Wisconsin Card Sorting Test measuring executive function, myoclonus, and postural tremor.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Spinocerebellar ataxia type 27 (SCA27) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by early onset tremor, dyskinesia, and slowly progressive cerebellar ataxia.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Spinocerebellar ataxia type 27 (SCA27) is a very rare subtype of type I autosomal dominant cerebellar ataxia. It is characterized by early onset tremor, dyskinesia, and slowly progressive cerebellar ataxia.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
An autosomal dominant cerebellar ataxia type III that is characterized by a slowly progressive and relatively pure ataxia.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
An autosomal dominant cerebellar ataxia type III that is characterized by a slowly progressive and relatively pure ataxia.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
An autosomal dominant cerebellar ataxia type 1 that is characterized by ataxia and cognitive impairment. Azoospermia is a typical feature in affected males.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
An autosomal dominant cerebellar ataxia type 1 that is characterized by ataxia and cognitive impairment. Azoospermia is a typical feature in affected males.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
An autosomal dominant cerebellar ataxia type I that is characterized by papulosquamous, ichthyosiform plaques on the limbs appearing shortly after birth and later manifestations including progressive ataxia, dysarthria, nystagmus and decreased reflexes.	Associated morphology	False	dégénérescence	Inferred relationship	Some	6
An autosomal dominant cerebellar ataxia type I that is characterized by papulosquamous, ichthyosiform plaques on the limbs appearing shortly after birth and later manifestations including progressive ataxia, dysarthria, nystagmus and decreased reflexes.	Associated morphology	False	dégénérescence	Inferred relationship	Some	4
An autosomal dominant cerebellar ataxia type 1 that is characterized by the adult-onset of progressive gait and limb ataxia, dysarthria, ocular dysmetria, intention tremor of hands, hyperreflexia and spasmodic torticollis.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
An autosomal dominant cerebellar ataxia type 1 that is characterized by the adult-onset of progressive gait and limb ataxia, dysarthria, ocular dysmetria, intention tremor of hands, hyperreflexia and spasmodic torticollis.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
An autosomal dominant cerebellar ataxia type 1 that is characterized by a cerebellar syndrome along with altered vertical eye movements.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
An autosomal dominant cerebellar ataxia type 1 that is characterized by a cerebellar syndrome along with altered vertical eye movements.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
An autosomal dominant cerebellar ataxia type III that is characterized by the early onset of cerebellar signs with eye movement abnormalities and a very slow disease progression.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
An autosomal dominant cerebellar ataxia type III that is characterized by the early onset of cerebellar signs with eye movement abnormalities and a very slow disease progression.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Vogt's limbal girdle, type I (finding)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
A rare syndromic, inherited form of sideroblastic anemia characterized by mild to moderate anemia (with hypochromia and microcytosis) and early-onset, non- or slowly progressive spinocerebellar ataxia.	Associated morphology	False	dégénérescence	Inferred relationship	Some	5
X-linked spinocerebellar ataxia type 3 is a form of spinocerebellar degeneration characterized by onset in infancy of hypotonia, ataxia, sensorineural deafness, developmental delay, esotropia, and optic atrophy, and by a progressive course leading to death in childhood. It has been described in one family with at least six affected males from five different sibships (connected through carrier females). It is transmitted as an X-linked recessive trait.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
X-linked spinocerebellar ataxia type 3 is a form of spinocerebellar degeneration characterized by onset in infancy of hypotonia, ataxia, sensorineural deafness, developmental delay, esotropia, and optic atrophy, and by a progressive course leading to death in childhood. It has been described in one family with at least six affected males from five different sibships (connected through carrier females). It is transmitted as an X-linked recessive trait.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
A rare X-linked spinocerebellar ataxia characterized by ataxia, pyramidal tract signs and adult-onset dementia. The disease manifests during early childhood with delayed walking and tremor. The pyramidal signs appear progressively and by adulthood memory problems and dementia gradually become apparent.	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
A rare X-linked spinocerebellar ataxia characterized by ataxia, pyramidal tract signs and adult-onset dementia. The disease manifests during early childhood with delayed walking and tremor. The pyramidal signs appear progressively and by adulthood memory problems and dementia gradually become apparent.	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
A rare genetic multiple congenital anomalies/dysmorphic syndrome characterized by developmental delay, neuropathic visceral dysmotility (resulting in neurogenic megacystis and sometimes chronic intestinal pseudo-obstruction syndrome), intracerebral calcifications, and dysmorphic facial features (including broad forehead, downslanted palpebral fissures, strabismus, protruding and low-set ears, and retrognathia). Microcephaly and renal abnormalities have also been reported.	Associated morphology	False	dégénérescence	Inferred relationship	Some	5
Bilateral osteoarthritis of first carpometacarpal joint	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Bilateral osteoarthritis of first carpometacarpal joint	Associated morphology	False	dégénérescence	Inferred relationship	Some	3
Osteoarthritis of joint of left shoulder region (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Osteoarthritis of joint of left wrist (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Osteoarthritis of joint of right ankle and/or foot (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Osteoarthritis of joint of right elbow (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Osteoarthritis of left hip joint (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Osteoarthritis of left knee joint (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Osteoarthritis of joint of left ankle (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Osteoarthritis of joint of left hand (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Osteoarthritis of joint of right hand (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Osteoarthritis of joint of right shoulder region (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Osteoarthritis of joint of right wrist (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Osteoarthritis of right hip joint (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Osteoarthritis of right knee joint (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
A rare, genetic, neurological disorder characterized by the association of slowly progressive spinocerebellar degeneration and corneal dystrophy, manifesting with bilateral corneal opacities (which lead to severe visual impairment), mild intellectual disability, ataxia, gait disturbances, and tremor. Additional manifestations include facial dysmorphism (i.e. triangular face, ptosis, low-set, posteriorly angulated ears, and micrognathia), as well as mild upper motor neuron involvement with hypertonia, lower limb hyperreflexia and extensor plantar responses. There have been no further descriptions in the literature since 1985.	Associated morphology	False	dégénérescence	Inferred relationship	Some	5
Neuronal ceroid lipofuscinosis due to deficiency of cathepsin D (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	2
Osteoarthritis of right foot (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Osteoarthritis of left foot (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
A rare genetic neurological disorder characterized by infantile to childhood onset of progressive sensory neuropathy in association with spastic paraplegia and mutilating acropathy. Patients present lower limb spasticity and progressive severe sensory loss leading to chronic ulcerations in both upper and lower limbs. Electrophysiological studies are consistent with axonal sensory neuropathy, and nerve biopsy shows axonopathy with loss of myelinated nerve fibers of all diameters as well as of unmyelinated axons.	Associated morphology	False	dégénérescence	Inferred relationship	Some	6
A rare syndromic, inherited form of sideroblastic anemia characterized by mild to moderate anemia (with hypochromia and microcytosis) and early-onset, non- or slowly progressive spinocerebellar ataxia.	Associated morphology	False	dégénérescence	Inferred relationship	Some	6
Morton's neuroma (morphologic abnormality)	Is a	False	dégénérescence	Inferred relationship	Some
Posterior vitreous degeneration of right eye (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Posterior vitreous degeneration of left eye (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	1
Posterior vitreous degeneration of bilateral eyes (disorder)	Associated morphology	False	dégénérescence	Inferred relationship	Some	2

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Reference Sets

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Id	Description	Lang	Type	Status	Case?	Module
55660014	Degeneration	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
55662018	Degenerative change	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
764753012	Degeneration (morphologic abnormality)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
12461000077110	dégénérescence	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module