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36176003: Thrombin (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Activated coagulation factor\Thrombin
\Substance categorized by disposition\Enzyme\Hydrolase\Peptide hydrolase\Serine protease\Thrombin

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Hematologic agent (substance)\...

\Blood derivative (substance)\Coagulation related substance (substance)\...

\Activated coagulation factor\Thrombin

\Fibrinolytic system factor\Thrombin

\Coagulation protein\Thrombin

\Hemostatic agent (substance)\Thrombin

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Plasma protein (substance)\Coagulation protein\Thrombin

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Plasma protein (substance)\Coagulation protein\Thrombin

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Thrombin	Is a	Coagulation protein	true	Inferred relationship	Some
Thrombin	Is a	Activated coagulation factor	true	Inferred relationship	Some
Thrombin	Is a	Serine protease	true	Inferred relationship	Some
Thrombin	Is a	Fibrinolytic system factor	true	Inferred relationship	Some
Thrombin	Is a	Hemostatic agent (substance)	true	Inferred relationship	Some
Thrombin	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Activated coagulation factor (disposition)	true	Inferred relationship	Some
Thrombin	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Serine protease (disposition)	true	Inferred relationship	Some
Thrombin	Is a	Hydrolase	false	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Thrombin time ratio (procedure)	Component	True	Thrombin	Inferred relationship	Some	1
Bovine thrombin (substance)	Is a	True	Thrombin	Inferred relationship	Some
Product containing human fibrinogen and thrombin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Thrombin	Inferred relationship	Some	1
Product containing thrombin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Thrombin	Inferred relationship	Some	1
Biological active component+thrombin sealant solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thrombin	Inferred relationship	Some
Biological active component 5mL vial/thrombin sealant solution 5mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thrombin	Inferred relationship	Some
Biological active component 1mL vial/thrombin sealant solution 1mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thrombin	Inferred relationship	Some
Biological active component 2mL vial/thrombin sealant solution 2mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thrombin	Inferred relationship	Some
Human thrombin topical solution 5mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thrombin	Inferred relationship	Some
Human thrombin topical solution 20mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thrombin	Inferred relationship	Some
Repair of pseudoaneurysm by injection of thrombin (procedure)	Direct substance	False	Thrombin	Inferred relationship	Some	1
Human thrombin topical solution 2mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thrombin	Inferred relationship	Some
Recombinant thrombin (substance)	Is a	False	Thrombin	Inferred relationship	Some
Percutaneous injection of thrombin using fluoroscopic guidance (procedure)	Direct substance	False	Thrombin	Inferred relationship	Some	1
Sealer protein concentrate/thrombin solution 2mL pack	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thrombin	Inferred relationship	Some
Sealer protein concentrate/thrombin solution 4mL pack	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thrombin	Inferred relationship	Some
Sealer protein concentrate/thrombin solution 10mL pack	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thrombin	Inferred relationship	Some
Repair of pseudoaneurysm by injection of thrombin (procedure)	Direct substance	True	Thrombin	Inferred relationship	Some	2
Injection of thrombin using ultrasound guidance (procedure)	Direct substance	False	Thrombin	Inferred relationship	Some	1
Percutaneous injection of thrombin using fluoroscopic guidance (procedure)	Direct substance	True	Thrombin	Inferred relationship	Some	1
Injection of thrombin using ultrasound guidance (procedure)	Direct substance	True	Thrombin	Inferred relationship	Some	1
Injection of thrombin into pseudoaneurysm of limb (procedure)	Direct substance	False	Thrombin	Inferred relationship	Some	1
Repair of pseudoaneurysm by injection of thrombin (procedure)	Direct substance	False	Thrombin	Inferred relationship	Some	2
Injection of thrombin into pseudoaneurysm of limb (procedure)	Direct substance	True	Thrombin	Inferred relationship	Some	1
Injection of thrombin for femoral artery pseudoaneurysm using imaging guidance (procedure)	Direct substance	True	Thrombin	Inferred relationship	Some	2
Fluoroscopy guided injection of thrombin	Direct substance	True	Thrombin	Inferred relationship	Some	3
Injection of thrombin into pseudoaneurysm of extremity using fluoroscopic guidance (procedure)	Direct substance	True	Thrombin	Inferred relationship	Some	2
Injection of thrombin	Direct substance	True	Thrombin	Inferred relationship	Some	1
Product containing only thrombin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Thrombin	Inferred relationship	Some	1
Human fibrinogen and thrombin only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Thrombin	Inferred relationship	Some	1
Product containing only thrombin in cutaneous dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Thrombin	Inferred relationship	Some	1
Product containing thrombin in cutaneous dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Thrombin	Inferred relationship	Some	1

Reference Sets

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Id	Description	Lang	Type	Status	Case?	Module
60365011	Thrombin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
60366012	Fibrinogenase	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
767897014	Thrombin (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
920101000195119	trombina	it	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
11871000188116	thrombine humaine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module