371014004: Asparaginase (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Enzyme\Hydrolase\Asparaginase (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Asparaginase (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Asparaginase (substance)

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Asparaginase (substance)

\Biological substance\Protein and/or protein derivative\Protein\Asparaginase (substance)
\Biological substance\Polypeptide\Protein\Asparaginase (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

1196310017 Asparaginase (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

1209727011 Asparaginase en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3744793013 L-asparagine amidohydrolase en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

3744794019 L-asparaginase en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

55061000195119 asparaginasi it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

189181000077112 asparaginase fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

69611000195119 Asparaginase de Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Asparaginase (substance)	Is a	Hydrolase	true	Inferred relationship	Some
Asparaginase (substance)	Is a	classe d'allergènes	false	Inferred relationship	Some
Asparaginase (substance)	Is a	allergène médicamenteux	false	Inferred relationship	Some
Asparaginase (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some
Asparaginase (substance)	Is a	agent enzymatique	false	Inferred relationship	Some
Asparaginase (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Hydrolase (disposition)	true	Inferred relationship	Some
Asparaginase (substance)	Is a	Protein	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Crisantaspase	Is a	True	Asparaginase (substance)	Inferred relationship	Some
Escherichia coli asparaginase (substance)	Is a	True	Asparaginase (substance)	Inferred relationship	Some
L-asparaginase	Is a	False	Asparaginase (substance)	Inferred relationship	Some
Pegaspargase	Is a	False	Asparaginase (substance)	Inferred relationship	Some
Neurotoxicity caused by L-asparaginase (disorder)	Causative agent (attribute)	True	Asparaginase (substance)	Inferred relationship	Some	1
Poisoning by L-asparaginase	Causative agent (attribute)	True	Asparaginase (substance)	Inferred relationship	Some	1
Crisantaspase adverse reaction	Causative agent (attribute)	False	Asparaginase (substance)	Inferred relationship	Some
L-asparaginase 10,000iu powder for injection solution 10mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Asparaginase (substance)	Inferred relationship	Some
Product containing asparaginase (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Asparaginase (substance)	Inferred relationship	Some	1
Asparaginase-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Asparaginase (substance)	Inferred relationship	Some	1
Escherichia coli asparaginase (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	False	Asparaginase (substance)	Inferred relationship	Some
Pegaspargase	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Asparaginase (substance)	Inferred relationship	Some
Asparaginase only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Asparaginase (substance)	Inferred relationship	Some	1
Product containing only asparaginase in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Asparaginase (substance)	Inferred relationship	Some	1
Product containing precisely asparaginase (as crisantaspase) 10000 unit/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Asparaginase (substance)	Inferred relationship	Some	1
Product containing precisely asparaginase 10000 unit/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Asparaginase (substance)	Inferred relationship	Some	1
Product containing precisely asparaginase 10000 unit/1 vial powder for conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Asparaginase (substance)	Inferred relationship	Some	1
Calaspargase pegol	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Asparaginase (substance)	Inferred relationship	Some

Reference Sets