Outbound Relationships |
Type |
Target |
Active |
Characteristic |
Refinability |
Group |
Values |
ACE inhibitor-aggravated angioedema |
Is a |
Allergic drug reaction |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Is a |
Drug-induced lesion |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Is a |
Angioedema |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Finding site |
Structure of immune system (body structure) |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Finding site |
Skin structure |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Associated morphology |
A raised, erythematous papule or cutaneous plaque, usually representing short-lived dermal edema. |
false |
Inferred relationship |
Some |
2 |
|
ACE inhibitor-aggravated angioedema |
Causative agent (attribute) |
Product containing angiotensin-converting enzyme inhibitor (product) |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Causative agent (attribute) |
Angiotensin-converting enzyme inhibitor |
false |
Inferred relationship |
Some |
4 |
|
ACE inhibitor-aggravated angioedema |
Causative agent (attribute) |
Pharmaceutical / biologic product (product) |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Is a |
All noxious and unintended responses to a medicinal product related to any dose should be considered adverse drug reactions (from US FDA Guideline for Industry, Clinical Safety Data Management: Definitions and Standards for Expedited Reporting). |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Associated morphology |
inflammation |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Is a |
Angiotensin-converting-enzyme inhibitor adverse reaction |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Is a |
Drug-induced lesion |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Causative agent (attribute) |
Pharmaceutical / biologic product (product) |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Is a |
réaction d'hypersensibilité non allergique |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Is a |
Drug-aggravated angioedema-urticaria (disorder) |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Associated morphology |
Eruption |
false |
Inferred relationship |
Some |
1 |
|
ACE inhibitor-aggravated angioedema |
Due to |
réaction d'hypersensibilité non immune |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Finding site |
Skin structure |
false |
Inferred relationship |
Some |
1 |
|
ACE inhibitor-aggravated angioedema |
Is a |
Non-allergic drug hypersensitivity disorder (disorder) |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Associated morphology |
Eruption |
false |
Inferred relationship |
Some |
1 |
|
ACE inhibitor-aggravated angioedema |
Finding site |
Skin structure |
false |
Inferred relationship |
Some |
1 |
|
ACE inhibitor-aggravated angioedema |
Pathological process (attribute) |
An immune or non-immune mediated pathological process that represents the underlying mechanism of hypersensitivity conditions. |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Is a |
A pathological nonimmune process generally directed towards a foreign substance, which results in tissue injury, which is usually transient. It is the realization of the pseudoallergic disposition. A variety of mechanisms such as direct histamine release, complement activation, cyclooxygenase activation and bradykinin generation may be involved. |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Pathological process (attribute) |
A type of non-immune hypersensitivity process that represents the underlying mechanism of pseudoallergic conditions. |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Due to |
A pathological nonimmune process generally directed towards a foreign substance, which results in tissue injury, which is usually transient. It is the realization of the pseudoallergic disposition. A variety of mechanisms such as direct histamine release, complement activation, cyclooxygenase activation and bradykinin generation may be involved. |
false |
Inferred relationship |
Some |
3 |
|
ACE inhibitor-aggravated angioedema |
Is a |
Angioedema due to disorder of kinin metabolism |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Associated morphology |
éruption cutanée |
false |
Inferred relationship |
Some |
2 |
|
ACE inhibitor-aggravated angioedema |
Finding site |
Skin structure |
false |
Inferred relationship |
Some |
2 |
|
ACE inhibitor-aggravated angioedema |
Associated morphology |
éruption cutanée |
false |
Inferred relationship |
Some |
1 |
|
ACE inhibitor-aggravated angioedema |
Causative agent (attribute) |
A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them. |
false |
Inferred relationship |
Some |
1 |
|
ACE inhibitor-aggravated angioedema |
Is a |
Chemical-induced dermatological disorder |
false |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Pathological process (attribute) |
An immune or non-immune mediated pathological process that represents the underlying mechanism of hypersensitivity conditions. |
true |
Inferred relationship |
Some |
1 |
|
ACE inhibitor-aggravated angioedema |
Associated morphology |
Angioedema |
true |
Inferred relationship |
Some |
1 |
|
ACE inhibitor-aggravated angioedema |
Causative agent (attribute) |
Angiotensin-converting enzyme inhibitor |
true |
Inferred relationship |
Some |
1 |
|
ACE inhibitor-aggravated angioedema |
Is a |
The disposition to develop an allergic or pseudoallergic reaction, the reaction itself or its consequences. |
true |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Is a |
Angioedema caused by angiotensin-converting-enzyme inhibitor (disorder) |
true |
Inferred relationship |
Some |
|
|
ACE inhibitor-aggravated angioedema |
Associated morphology |
Angioedema |
true |
Inferred relationship |
Some |
2 |
|
ACE inhibitor-aggravated angioedema |
Causative agent (attribute) |
Kallidin I |
true |
Inferred relationship |
Some |
2 |
|