372536007: Topotecan (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Topoisomerase inhibitor\Topotecan (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Topotecan (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Heterocyclic compound\Alkaloid (substance)\Topotecan (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Topotecan (substance)	Is a	Topoisomerase inhibitor	true	Inferred relationship	Some
Topotecan (substance)	Is a	classe d'allergènes	false	Inferred relationship	Some
Topotecan (substance)	Is a	allergène médicamenteux	false	Inferred relationship	Some
Topotecan (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Topoisomerase inhibitor (disposition)	true	Inferred relationship	Some
Topotecan (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Topotecan (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Topotecan (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some
Topotecan (substance)	Is a	Alkaloid (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Topotecan hydrochloride	Is a	False	Topotecan (substance)	Inferred relationship	Some
Product containing topotecan (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Topotecan (substance)	Inferred relationship	Some	1
Topotecan (as topotecan hydrochloride) 4 mg powder for solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan (substance)	Inferred relationship	Some
Topotecan 1mg powder for infusion solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan (substance)	Inferred relationship	Some
Topotecan (as topotecan hydrochloride) 1 mg powder for solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan (substance)	Inferred relationship	Some
Product containing topotecan in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Topotecan (substance)	Inferred relationship	Some	1
Topotecan-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Topotecan (substance)	Inferred relationship	Some	1
Product containing precisely topotecan 250 microgram/1 each conventional release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan (substance)	Inferred relationship	Some
Product containing precisely topotecan 1 milligram/1 each conventional release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan (substance)	Inferred relationship	Some
chlorhydrate de topotécan	Is a	False	Topotecan (substance)	Inferred relationship	Some
Product containing precisely topotecan 1 milligram/1 each conventional release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan (substance)	Inferred relationship	Some	1
Product containing precisely topotecan 1 milligram/1 each conventional release oral capsule	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Topotecan (substance)	Inferred relationship	Some	1
Product containing precisely topotecan 250 microgram/1 each conventional release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan (substance)	Inferred relationship	Some	1
Product containing precisely topotecan 250 microgram/1 each conventional release oral capsule	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Topotecan (substance)	Inferred relationship	Some	1
Product containing precisely topotecan 250 microgram/1 each conventional release oral capsule	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Topotecan (substance)	Inferred relationship	Some	1
Product containing precisely topotecan 1 milligram/1 each conventional release oral capsule	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Topotecan (substance)	Inferred relationship	Some	1
Topotecan (as topotecan hydrochloride) 4 mg powder for solution for injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Topotecan (substance)	Inferred relationship	Some	1
Topotecan (as topotecan hydrochloride) 1 mg powder for solution for injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Topotecan (substance)	Inferred relationship	Some	1
Topotecan hydrochloride	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Topotecan (substance)	Inferred relationship	Some
Product containing only topotecan (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Topotecan (substance)	Inferred relationship	Some	1
Topotecan only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Topotecan (substance)	Inferred relationship	Some	1
Product containing only topotecan in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Topotecan (substance)	Inferred relationship	Some	1
Product containing precisely topotecan (as topotecan hydrochloride) 1 milligram/1 each conventional release oral capsule (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Topotecan (substance)	Inferred relationship	Some	1
Product containing precisely topotecan (as topotecan hydrochloride) 250 microgram/1 each conventional release oral capsule (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Topotecan (substance)	Inferred relationship	Some	1
Topotecan (as topotecan hydrochloride) 1 mg powder for solution for infusion vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Topotecan (substance)	Inferred relationship	Some	1
Topotecan (as topotecan hydrochloride) 1 mg powder for solution for infusion and/or injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Topotecan (substance)	Inferred relationship	Some	1
Product containing precisely topotecan (as topotecan hydrochloride) 4 milligram/1 vial powder for conventional release solution for infusion and/or injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Topotecan (substance)	Inferred relationship	Some	1
Topotecan (as topotecan hydrochloride) 4 mg powder for solution for infusion vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Topotecan (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1197829012	Topotecan (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1211069010	Topotecan	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
56031000195119	topotecan	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
846861000172112	topotécane	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
1119651000241112	topotécan	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
71141000195118	Topotecan	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module