372586001: Hypotensive agent (substance)

SNOMED CT Concept\Substance\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Cardiovascular agent (substance)\Hypotensive agent (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Hypotensive agent (substance)	Is a	Cardiovascular agent (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Betahistidine	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Benzoquinonium	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Chlorisondamine	Is a	False	Hypotensive agent (substance)	Inferred relationship	Some
Pentolinium	Is a	False	Hypotensive agent (substance)	Inferred relationship	Some
Mebutamate	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Trimethidinium	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Hexamethonium	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Tienilic acid	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Pentamethonium bromide	Is a	False	Hypotensive agent (substance)	Inferred relationship	Some
Protoveratrine A	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Cryptenamine	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Angiotensin-converting enzyme inhibitor	Is a	False	Hypotensive agent (substance)	Inferred relationship	Some
Centrally acting hypotensive agent (substance)	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Vasodilator (substance)	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Mecamylamine (substance)	Is a	False	Hypotensive agent (substance)	Inferred relationship	Some
Nitroprusside (substance)	Is a	False	Hypotensive agent (substance)	Inferred relationship	Some
Rauwolfia alkaloid (substance)	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Angiotensin II receptor antagonist	Is a	False	Hypotensive agent (substance)	Inferred relationship	Some
Pargyline (substance)	Is a	False	Hypotensive agent (substance)	Inferred relationship	Some
Trimetaphan	Is a	False	Hypotensive agent (substance)	Inferred relationship	Some
médicament antihypertenseur	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Adrenergic neurone blocking drug poisoning	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Amiloride and loop diuretic adverse reaction	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Antihypertensive adverse reaction	Causative agent (attribute)	True	Hypotensive agent (substance)	Inferred relationship	Some	1
Adrenergic neurone blocking drug adverse reaction	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some	1
Ganglion-blocking drug adverse reaction	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Trimetaphan adverse reaction	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Amiloride and loop diuretic allergy	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Antihypertensive allergy	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Adrenergic neurone blocking drug allergy	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Ganglion-blocking drug allergy	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Allergy to trimethaphan	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Antihypertensive overdose	Causative agent (attribute)	True	Hypotensive agent (substance)	Inferred relationship	Some	1
Adrenergic neurone blocking drug overdose	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some	1
Accidental antihypertensive overdose	Causative agent (attribute)	True	Hypotensive agent (substance)	Inferred relationship	Some	1
Intentional antihypertensive overdose	Causative agent (attribute)	True	Hypotensive agent (substance)	Inferred relationship	Some	1
Antihypertensive overdose of undetermined intent	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some	1
fœtus ou nouveau-né affecté par l'usage maternel de médicament antihypertenseur	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some	1
Calcium-channel blocker+angiotensin-converting enzyme inhibitor	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Product containing felodipine and ramipril (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Felodipine 2.5 mg and ramipril 2.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Felodipine 5 mg and ramipril 5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Centrally acting antihypertensive drug	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Product containing adrenergic neurone blocker (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Product containing bethanidine sulfate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Product containing precisely betanidine 10 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Product containing ganglion blocker (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Trimetaphan camsylate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
camsilate de trimétaphan 50 mg/mL, ampoule de 5 mL de solution pour injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Other antihypertensives	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Antihypertensives+barbiturates	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Product containing betanidine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Product containing trimetaphan (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Angiotensin II receptor antagonist+diuretic	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
olmésartan médoxomil	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Product containing olmesartan (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Olmesartan medoxomil 5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Olmesartan medoxomil 20 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Olmesartan medoxomil 40 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Deserpidine (substance)	Is a	False	Hypotensive agent (substance)	Inferred relationship	Some
Guanethidine (substance)	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Metirosine	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Bethanidine sulfate	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Imidazoline receptor agonist	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Debrisoquine (substance)	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Product containing angiotensin-converting enzyme inhibitor (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Product containing angiotensin II receptor antagonist (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Product containing eplerenone (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Adverse reaction to reserpine	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Adverse reaction to other antihypertensives	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Adverse reaction to antihypertensives NOS	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Eplerenone 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Eplerenone 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Inspra 50mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Inspra 25mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Eplerenone 100 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Inspra 100mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Angiotensin II receptor antagonist adverse reaction (disorder)	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Hydrochlorothiazide 12.5 mg and telmisartan 40 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Hydrochlorothiazide 12.5 mg and telmisartan 80 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Olmesartan medoxomil 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Eplerenone (substance)	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Adverse reaction to ganglion blocking drug	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Adverse reaction to pentamethonium bromide	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Adverse reaction to trimetaphan camsylate	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Adverse reaction to ganglion blockers NOS	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Substance with beta adrenergic receptor antagonist mechanism of action (substance)	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Fetal captopril/enalapril syndrome	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some	3
Ganglion blocking agent	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Betanidine	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Ivabradine (substance)	Is a	False	Hypotensive agent (substance)	Inferred relationship	Some
Poisoning caused by antihypertensive agent	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some	1
Adrenergic neurone blocking drug poisoning	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some	1
[X]Poisoning by other antihypertensive drugs, not elsewhere classified	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some
Renin inhibitor	Is a	False	Hypotensive agent (substance)	Inferred relationship	Some
Ketanserin	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some
Antihypertensive allergy	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some	1
Adrenergic neurone blocking drug allergy	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some	1
Losartan allergy	Causative agent (attribute)	False	Hypotensive agent (substance)	Inferred relationship	Some	1
Product containing renin inhibitor (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Hypotensive agent (substance)	Inferred relationship	Some
Endothelin receptor antagonist	Is a	True	Hypotensive agent (substance)	Inferred relationship	Some

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Id	Description	Lang	Type	Status	Case?	Module
1197880013	Hypotensive agent (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1211115010	Hypotensive agent	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2579475017	Antihypertensive agent	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
939541000195119	agente ipotensivo	it	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
189611000077110	agent hypertenseur	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
672641000274112	Antihypertensivum	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module