372588000: Naproxen (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Substance with prostaglandin-endoperoxide synthase inhibitor mechanism of action (substance)\...

\Cyclooxygenase-1 inhibitor\Naproxen (substance)

\Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)\Naproxen (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Substance with prostaglandin-endoperoxide synthase inhibitor mechanism of action (substance)\Cyclooxygenase-1 inhibitor\Naproxen (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Substance with prostaglandin-endoperoxide synthase inhibitor mechanism of action (substance)\Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)\Naproxen (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Analgesic (substance)\Non-opioid analgesic (substance)\Non-steroidal anti-inflammatory agent (substance)\Cyclooxygenase-1 inhibitor\Naproxen (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Analgesic (substance)\Non-opioid analgesic (substance)\Non-steroidal anti-inflammatory agent (substance)\Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)\Naproxen (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Hydrocarbon\Aromatic hydrocarbon\Polyaromatic hydrocarbon\Naphthalene\Naproxen (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Naproxen (substance)	Is a	Non-steroidal anti-inflammatory agent (substance)	false	Inferred relationship	Some
Naproxen (substance)	Is a	Propionic acid derivative anti-inflammatory agent	false	Inferred relationship	Some
Naproxen (substance)	Is a	Propionic acid and/or propionic acid derivative (substance)	false	Inferred relationship	Some
Naproxen (substance)	Is a	Cyclooxygenase-1 inhibitor	true	Inferred relationship	Some
Naproxen (substance)	Is a	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	true	Inferred relationship	Some
Naproxen (substance)	Is a	Naphthalene	true	Inferred relationship	Some
Naproxen (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Cyclooxygenase-2 inhibitor	true	Inferred relationship	Some
Naproxen (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Cyclooxygenase-1 inhibitor	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Naproxen sodium	Is a	False	Naproxen (substance)	Inferred relationship	Some
Naproxen measurement	Component	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing naproxen (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Naproxen poisoning	Causative agent (attribute)	True	Naproxen (substance)	Inferred relationship	Some	1
Accidental naproxen poisoning	Causative agent (attribute)	False	Naproxen (substance)	Inferred relationship	Some
Intentional naproxen poisoning	Causative agent (attribute)	False	Naproxen (substance)	Inferred relationship	Some
intoxication par le naproxène d'intention indéterminée	Causative agent (attribute)	False	Naproxen (substance)	Inferred relationship	Some	1
Naproxen adverse reaction	Causative agent (attribute)	False	Naproxen (substance)	Inferred relationship	Some
Allergy to naproxen (finding)	Causative agent (attribute)	False	Naproxen (substance)	Inferred relationship	Some
Naproxen overdose	Causative agent (attribute)	True	Naproxen (substance)	Inferred relationship	Some	1
Accidental naproxen overdose	Causative agent (attribute)	True	Naproxen (substance)	Inferred relationship	Some	1
Intentional naproxen overdose	Causative agent (attribute)	True	Naproxen (substance)	Inferred relationship	Some	1
surdose de naproxène d'intention indéterminée	Causative agent (attribute)	False	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 250 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Product containing precisely naproxen 500 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Product containing precisely naproxen 250 milligram/1 each gastro-resistant oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Naproxen 500mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Naproxen 375mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Naproxen 25 mg/mL oral suspension	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Product containing precisely naproxen 500 milligram/1 each conventional release rectal suppository (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Product containing precisely naproxen 200 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Product containing precisely naproxen 375 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Naproxen 500mg tablet and misoprostol 200micrograms tablet pack	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Product containing misoprostol and naproxen (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing lansoprazole and naproxen (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Lansoprazole 15mg m/r capsule/naproxen 375mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Lansoprazole 15mg m/r capsule/naproxen 500mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Product containing naproxen and pseudoephedrine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Naproxen sodium 220mg/pseudoephedrine 120mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Adverse reaction to naproxen	Causative agent (attribute)	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 500 milligram/1 each gastro-resistant oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Aleve 200mg capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Naproxen 200 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Intentional naproxen poisoning	Causative agent (attribute)	True	Naproxen (substance)	Inferred relationship	Some	1
Naproxen 200mg/pseudoephedrine 120mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Lansoprazole 15mg m/r capsule/naproxen 250mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Naproxen-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Naproxen-containing product in rectal dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Accidental poisoning by naproxen	Causative agent (attribute)	True	Naproxen (substance)	Inferred relationship	Some	1
Esomeprazole magnesium 20mg + naproxen 375mg delayed release tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Esomeprazole magnesium 20mg + naproxen 500mg delayed release tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Product containing esomeprazole magnesium and naproxen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Allergy to naproxen (finding)	Causative agent (attribute)	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 250 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 250 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 500 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 500 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 200 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 200 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 375 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 375 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Naproxen (substance)	Inferred relationship	Some	1
Naproxen 200 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some	1
Naproxen 200 mg oral capsule	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Naproxen (substance)	Inferred relationship	Some	1
Naproxen sodium	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Naproxen (substance)	Inferred relationship	Some
Naproxen 200mg/pseudoephedrine 120mg prolonged-release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Naproxen (substance)	Inferred relationship	Some
Product containing precisely naproxen 500 milligram/1 each conventional release rectal suppository (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 500 milligram/1 each conventional release rectal suppository (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 250 milligram/1 each gastro-resistant oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 250 milligram/1 each gastro-resistant oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen (as naproxen sodium) 500 milligram/1 each gastro-resistant oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 375 milligram/1 each gastro-resistant oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 375 milligram/1 each gastro-resistant oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 500 milligram/1 each gastro-resistant oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 500 milligram/1 each gastro-resistant oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 250 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 200 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Naproxen (substance)	Inferred relationship	Some	1
Naproxen 200 mg oral capsule	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 500 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen 375 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Naproxen (substance)	Inferred relationship	Some	1
Product containing naproxen and sumatriptan (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Naproxen- and sumatriptan-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing esomeprazole and naproxen in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing esomeprazole and naproxen (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Naproxen 25 mg/mL oral suspension	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Naproxen (substance)	Inferred relationship	Some	1
Naproxen 25 mg/mL oral suspension	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Naproxen (substance)	Inferred relationship	Some	1
Esomeprazole and naproxen only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing only naproxen and sumatriptan (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing only lansoprazole and naproxen (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing only misoprostol and naproxen (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Naproxen only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing only naproxen and pseudoephedrine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Naproxen and sumatriptan only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Naproxen only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing only naproxen in rectal dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing only esomeprazole and naproxen in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen (as naproxen sodium) 375 milligram/1 each gastro-resistant oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely esomeprazole (as esomeprazole magnesium) 20 milligram and naproxen 500 milligram/1 each gastro-resistant oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely esomeprazole (as esomeprazole magnesium) 20 milligram and naproxen 500 milligram/1 each gastro-resistant oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely esomeprazole (as esomeprazole magnesium) 20 milligram and naproxen (as naproxen sodium) 375 milligram/1 each gastro-resistant oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen (as naproxen sodium) 500 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen (as naproxen sodium) 250 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen (as naproxen sodium) 375 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Naproxen (substance)	Inferred relationship	Some	1
Product containing precisely naproxen (as naproxen sodium) 200 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Naproxen (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1197882017	Naproxen (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1211117019	Naproxen	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
52541000195117	naprossene	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
827191000172110	naproxène	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
66901000195118	Naproxen	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module