| Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
| Dental fluoride treatment |
Direct substance |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Topical application of fluoride including prophylaxis, child |
Direct substance |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Topical application of fluoride including prophylaxis, adult |
Direct substance |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Topical application of fluoride excluding prophylaxis, adult |
Direct substance |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Sodium fluoride 1.1% cream |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Sodium fluoride 0.619% toothpaste |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Serum fluoride number (procedure) |
Component |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Fluoride toothpaste |
Is a |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Dental fluoride varnish |
Is a |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Dental fluoride gel |
Is a |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Dental fluoride solution |
Is a |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Carbonyl fluoride |
Is a |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Sodium fluoride |
Is a |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Fluoride ion 1.2% oropharyngeal foam |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Fluoride ion 1.23% oropharyngeal foam |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Stannous fluoride |
Is a |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Fluoride-containing product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Product containing fluoride in oropharyngeal dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Quantitative measurement of mass concentration of fluoride in urine specimen (procedure) |
Component |
False |
Fluoride (substance) |
Inferred relationship |
Some |
2 |
| Allergy to fluoride |
Causative agent (attribute) |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Sodium monofluorophosphate |
Is a |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Fluoride 1.1 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Fluoride 1.1 mg oral tablet |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Product containing precisely fluoride 2.2 milligram/1 each conventional release oral tablet (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Product containing precisely fluoride 2.2 milligram/1 each conventional release oral tablet (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Fluoride 550 microgram oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Fluoride 550 microgram oral tablet |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Increase or decrease in fluoride content of the diet. |
Direct substance |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Providing fluoride based on suboptimal food or fluid intake, iatrogenic deficiency or medical diagnosis. |
Direct substance |
False |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Acidulated phosphate fluoride |
This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Stannous fluoride |
This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Carbonyl fluoride |
This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Sodium fluoride |
This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Sodium monofluorophosphate |
This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Application of dental fluoride varnish |
Direct substance |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Topical application of fluoride including prophylaxis, child |
Direct substance |
True |
Fluoride (substance) |
Inferred relationship |
Some |
2 |
| Topical application of fluoride including prophylaxis, adult |
Direct substance |
True |
Fluoride (substance) |
Inferred relationship |
Some |
2 |
| Topical application of fluoride excluding prophylaxis, child |
Direct substance |
False |
Fluoride (substance) |
Inferred relationship |
Some |
2 |
| Topical application of fluoride excluding prophylaxis, adult |
Direct substance |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Topical application of fluoride - tooth |
Direct substance |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Fluoride ion |
Is a |
True |
Fluoride (substance) |
Inferred relationship |
Some |
|
| Fluoride 1.1 mg oral tablet |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Product containing precisely fluoride 2.2 milligram/1 each conventional release oral tablet (clinical drug) |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Fluoride 550 microgram oral tablet |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Fluoride only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Product containing only fluoride in oral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Product containing only fluoride in oromucosal dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| The approximate quantity of intake in one day of fluoride. |
This attribute specifies the resulting output of the process characterized by the observed feature. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
6 |
| Rinsing of mouth using fluoride treatment |
Direct substance |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Fluoride intake (observable entity) |
This attribute specifies the resulting output of the process characterized by the observed feature. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
2 |
| Fluoride-containing product in oromucosal dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| The known quantity of intake of fluoride from all sources including food, beverages, breastmilk/formula, supplements, and via enteral and parenteral routes. |
This attribute specifies the resulting output of the process characterized by the observed feature. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
5 |
| Estimated quantity of fluoride needed for nutritional adequacy in one day. |
This attribute specifies the resulting output of the process characterized by the observed feature. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
4 |
| The approximate quantity of intake in one day of fluoride. |
This attribute specifies an entity that the process which the property characterizes specifically acts on. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
3 |
| Fluoride intake (observable entity) |
This attribute specifies an entity that the process which the property characterizes specifically acts on. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
2 |
| The known quantity of intake of fluoride from all sources including food, beverages, breastmilk/formula, supplements, and via enteral and parenteral routes. |
This attribute specifies an entity that the process which the property characterizes specifically acts on. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
5 |
| Estimated quantity of fluoride needed for nutritional adequacy in one day. |
This attribute specifies an entity that the process which the property characterizes specifically acts on. |
False |
Fluoride (substance) |
Inferred relationship |
Some |
4 |
| Application of silver diamine fluoride to tooth via topical route (procedure) |
Direct substance |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Topical application of fluoride excluding prophylaxis, child |
Direct substance |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Estimated quantity of fluoride needed for nutritional adequacy in one day. |
This attribute specifies an entity that the process which the property characterizes specifically acts on. |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Fluoride intake (observable entity) |
This attribute specifies an entity that the process which the property characterizes specifically acts on. |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| The approximate quantity of intake in one day of fluoride. |
This attribute specifies an entity that the process which the property characterizes specifically acts on. |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| The known quantity of intake of fluoride from all sources including food, beverages, breastmilk/formula, supplements, and via enteral and parenteral routes. |
This attribute specifies an entity that the process which the property characterizes specifically acts on. |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
| Quantitative measurement of mass concentration of fluoride in urine specimen (procedure) |
Component |
True |
Fluoride (substance) |
Inferred relationship |
Some |
1 |
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