372642003: Ketotifen (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with receptor antagonist mechanism of action (substance)\Histamine receptor antagonist\Piperidine derivative antihistamine\Ketotifen (substance)
\Substance categorized by disposition\Substance with receptor antagonist mechanism of action (substance)\Histamine receptor antagonist\Histamine H1 receptor antagonist\Ketotifen (substance)
\Substance categorized by disposition\Mast cell stabiliser\Ketotifen (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Mast cell stabiliser\Ketotifen (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative (substance)\Piperidine derivative antihistamine\Ketotifen (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative (substance)\Piperidine derivative antihistamine\Ketotifen (substance)
\Organic compound\Organic nitrogen compound\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative (substance)\Piperidine derivative antihistamine\Ketotifen (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Ketotifen (substance)	Is a	Histamine receptor antagonist	false	Inferred relationship	Some
Ketotifen (substance)	Is a	cromoglycate et anti-allergique apparenté	false	Inferred relationship	Some
Ketotifen (substance)	Is a	Histamine H1 receptor antagonist	true	Inferred relationship	Some
Ketotifen (substance)	Is a	Sedating antihistamine	false	Inferred relationship	Some
Ketotifen (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Histamine H1 receptor antagonist (disposition)	true	Inferred relationship	Some
Ketotifen (substance)	Is a	Piperidine derivative antihistamine	true	Inferred relationship	Some
Ketotifen (substance)	Is a	Mast cell stabiliser	true	Inferred relationship	Some
Ketotifen (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Mast cell stabilizer (disposition)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Ketotifen fumarate	Is a	False	Ketotifen (substance)	Inferred relationship	Some
Ketotifen fumarate ophthalmic agent	Is a	False	Ketotifen (substance)	Inferred relationship	Some
Ketotifen adverse reaction	Causative agent (attribute)	True	Ketotifen (substance)	Inferred relationship	Some	1
Allergy to ketotifen (finding)	Causative agent (attribute)	False	Ketotifen (substance)	Inferred relationship	Some
Ketotifen [asthma prophylaxis]	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ketotifen (substance)	Inferred relationship	Some
Product containing precisely ketotifen 1 milligram/1 each conventional release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ketotifen (substance)	Inferred relationship	Some
Product containing precisely ketotifen 1 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ketotifen (substance)	Inferred relationship	Some
Ketotifen 1mg/5mL elixir	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ketotifen (substance)	Inferred relationship	Some
Ketotifen [antihistamine]	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ketotifen (substance)	Inferred relationship	Some
Product containing ketotifen (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ketotifen (substance)	Inferred relationship	Some	1
Ketotifen [eye]	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ketotifen (substance)	Inferred relationship	Some
Ketotifen 250micrograms/mL eye drops	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ketotifen (substance)	Inferred relationship	Some
Product containing precisely ketotifen (as ketotifen fumarate) 250 microgram/1 milliliter conventional release eye drops (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ketotifen (substance)	Inferred relationship	Some
Product containing ketotifen in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ketotifen (substance)	Inferred relationship	Some	1
Product containing ketotifen in ophthalmic dosage form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ketotifen (substance)	Inferred relationship	Some
Allergy to ketotifen (finding)	Causative agent (attribute)	True	Ketotifen (substance)	Inferred relationship	Some	1
Product containing precisely ketotifen 1 milligram/1 each conventional release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ketotifen (substance)	Inferred relationship	Some	1
Product containing precisely ketotifen 1 milligram/1 each conventional release oral capsule	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Ketotifen (substance)	Inferred relationship	Some	1
Product containing precisely ketotifen 1 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ketotifen (substance)	Inferred relationship	Some	1
Product containing precisely ketotifen 1 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Ketotifen (substance)	Inferred relationship	Some	1
Ketotifen fumarate	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Ketotifen (substance)	Inferred relationship	Some
Product containing precisely ketotifen 1 milligram/1 each conventional release oral capsule	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Ketotifen (substance)	Inferred relationship	Some	1
Product containing precisely ketotifen 1 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Ketotifen (substance)	Inferred relationship	Some	1
Product containing precisely ketotifen (as ketotifen fumarate) 250 microgram/1 milliliter conventional release eye drops (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Ketotifen (substance)	Inferred relationship	Some	1
Ketotifen-containing product in ocular dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ketotifen (substance)	Inferred relationship	Some	1
Ketotifen only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ketotifen (substance)	Inferred relationship	Some	1
Product containing only ketotifen in ocular dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ketotifen (substance)	Inferred relationship	Some	1
Product containing only ketotifen in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ketotifen (substance)	Inferred relationship	Some	1
Ketotifen (as ketotifen fumarate) 1 mg oral capsule	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Ketotifen (substance)	Inferred relationship	Some	1
Product containing precisely ketotifen (as ketotifen fumarate) 1 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Ketotifen (substance)	Inferred relationship	Some	1
Product containing precisely ketotifen 200 microgram/1 milliliter conventional release oral solution (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Ketotifen (substance)	Inferred relationship	Some	1
Product containing precisely ketotifen 200 microgram/1 milliliter conventional release oral solution (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Ketotifen (substance)	Inferred relationship	Some	1
Product containing precisely ketotifen (as ketotifen fumarate) 200 microgram/1 milliliter conventional release oral solution (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Ketotifen (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1197936012	Ketotifen (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1211170013	Ketotifen	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
59451000195111	ketotifene	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
819561000172114	kétotifène	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
74761000195118	Ketotifen	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module