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372669002: Alkylating agent (substance)

Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2018. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module
1197963013 Alkylating agent (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core
1211196010 Alkylating agent en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
189231000077118 agent alkylant fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

40 descendants. Search Descendants:

Expanded Value Set

Outbound Relationships Type Target Active Characteristic Refinability Group Values
Alkylating agent (substance) Is a Antineoplastic agent (substance) true Inferred relationship Some
Alkylating agent (substance) Is a Immunomodulator true Inferred relationship Some
Alkylating agent (substance) This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context. Alkylating agent (disposition) true Inferred relationship Some
Inbound Relationships Type Active Source Characteristic Refinability Group
Estramustine phosphate sodium Is a False Alkylating agent (substance) Inferred relationship Some
Uramustine Is a True Alkylating agent (substance) Inferred relationship Some
Triethylenemelamine (substance) Is a True Alkylating agent (substance) Inferred relationship Some
Pipobroman Is a True Alkylating agent (substance) Inferred relationship Some
Semustine Is a True Alkylating agent (substance) Inferred relationship Some
Estramustine phosphate Is a False Alkylating agent (substance) Inferred relationship Some
Ethyleneimine antineoplastic Is a False Alkylating agent (substance) Inferred relationship Some
Nitrogen mustard derivative (substance) Is a True Alkylating agent (substance) Inferred relationship Some
Nitrosurea (substance) Is a True Alkylating agent (substance) Inferred relationship Some
Triazene antineoplastic (substance) Is a True Alkylating agent (substance) Inferred relationship Some
Chlormethine Is a False Alkylating agent (substance) Inferred relationship Some
Poisoning by busulfan Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Alkylating drug poisoning Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some 1
Accidental busulphan poisoning Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Intentional busulfan poisoning Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
intoxication par le busulfan d'intention indéterminée Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Treosulfan poisoning Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Accidental treosulfan poisoning Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Intentional treosulfan poisoning Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Treosulfan poisoning of undetermined intent Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Alkylating drug adverse reaction (disorder) Causative agent (attribute) True Alkylating agent (substance) Inferred relationship Some 1
Busulfan adverse reaction Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Treosulfan adverse reaction Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some 2
Allergy to alkylating agent (finding) Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Allergy to busulfan Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Allergy to treosulfan (finding) Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Alkylating drug overdose Causative agent (attribute) True Alkylating agent (substance) Inferred relationship Some 1
Busulfan overdose Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Accidental busulphan overdose Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Intentional busulfan overdose Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
surdose de busulfan d'intention indéterminée Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Treosulfan overdose Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Accidental treosulphan overdose Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Intentional treosulfan overdose Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Treosulfan overdose of undetermined intent Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some
Mitobronitol Is a True Alkylating agent (substance) Inferred relationship Some
Mitobronitol Is a False Alkylating agent (substance) Inferred relationship Some
Alkyl sulfonate antineoplastic Is a False Alkylating agent (substance) Inferred relationship Some
Mitoxantrone (substance) Is a True Alkylating agent (substance) Inferred relationship Some
Bendamustine (substance) Is a False Alkylating agent (substance) Inferred relationship Some
Allergy to alkylating agent (finding) Causative agent (attribute) True Alkylating agent (substance) Inferred relationship Some 1
Pixantrone (substance) Is a True Alkylating agent (substance) Inferred relationship Some
Product containing alkylating agent (product) The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. True Alkylating agent (substance) Inferred relationship Some 1
A subgroup of therapy-related myeloid neoplasms (t-MN), associated with a treatment of an unrelated neoplastic or autoimmune disease with cytotoxic agents, like cyclophosphamid, platins, melphalan and others. The neoplastic cells typically harbour unbalanced aberrations of chromosomes 5 and 7 (monosomy 5/del(5q) and monosomy 7/del(7q)) or a complex karyotype. It usually presents with multilineage dysplasia and cytopenias 5-10 years after exposure, with symptoms related to the degree of bone marrow failure and the corresponding cytopenia (fatigue, bleeding and bruising, recurrent infections, bone pain). Causative agent (attribute) True Alkylating agent (substance) Inferred relationship Some 1
Allergy to treosulfan (finding) Causative agent (attribute) False Alkylating agent (substance) Inferred relationship Some 2
Busulfan (substance) Is a True Alkylating agent (substance) Inferred relationship Some
Thiotepa (substance) Is a True Alkylating agent (substance) Inferred relationship Some
Mitoxantrone hydrochloride (substance) Is a True Alkylating agent (substance) Inferred relationship Some
Streptozocin Is a True Alkylating agent (substance) Inferred relationship Some

This concept is not in any reference sets

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