Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Aciclovir sodium |
Is a |
False |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir adverse reaction |
Causative agent (attribute) |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Allergy to acyclovir |
Causative agent (attribute) |
False |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir [systemic] |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir 200 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Acyclovir 200mg/5mL s/f suspension |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir (as aciclovir sodium) 250 mg powder for solution for injection vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir 400 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Acyclovir 800mg dispersible tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir (as aciclovir sodium) 500 mg powder for solution for injection vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir 80 mg/mL oral suspension |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Acyclovir 200mg dispersible tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Acyclovir 400mg dispersible tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir 800 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
acyclovir 25 mg/mL, flacon de 10 mL pour perfusion |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
acyclovir 25 mg/mL, flacon de 20 mL pour perfusion |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
acyclovir 25 mg/mL, flacon de 40 mL pour perfusion |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir [eyes] |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir 30 mg/g eye ointment |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir [skin] |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Product containing precisely aciclovir 50 milligram/1 gram conventional release cutaneous cream (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir-containing product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing aciclovir in parenteral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing aciclovir in topical dosage form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir 200 mg oral capsule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Product containing precisely aciclovir 40 milligram/1 milliliter conventional release oral suspension (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir 50 mg/g cutaneous ointment |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Product containing aciclovir (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing aciclovir in ophthalmic dosage form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
|
Measurement of aciclovir |
Component |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Allergy to acyclovir |
Causative agent (attribute) |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 200 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 200 mg oral tablet |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 400 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 400 mg oral tablet |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 800 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 800 mg oral tablet |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 200 mg oral capsule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 200 mg oral capsule |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir sodium |
This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged. |
True |
Aciclovir |
Inferred relationship |
Some |
|
Aciclovir 800 mg oral tablet |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 200 mg oral tablet |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 400 mg oral tablet |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 200 mg oral capsule |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir (as aciclovir sodium) 250 mg powder for solution for injection vial |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir (as aciclovir sodium) 500 mg powder for solution for injection vial |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir 50 milligram/1 gram conventional release cutaneous cream (clinical drug) |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir 50 milligram/1 gram conventional release cutaneous cream (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 30 mg/g eye ointment |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 30 mg/g eye ointment |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir (as aciclovir sodium) 500 milligram/20 milliliter conventional release solution for infusion vial |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
False |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir (as aciclovir sodium) 1 gram/40 milliliter conventional release solution for infusion vial |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
False |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir (as aciclovir sodium) 250 milligram/10 milliliter conventional release solution for infusion vial |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
False |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing aciclovir in ocular dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir-containing product in cutaneous dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing only aciclovir in cutaneous dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing only aciclovir in parenteral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir only product in ocular dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir only product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir (as aciclovir sodium) 25 milligram/1 milliliter conventional release solution for infusion (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 50 mg/g cutaneous ointment |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 50 mg/g cutaneous ointment |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir 40 milligram/1 milliliter conventional release oral suspension (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir 40 milligram/1 milliliter conventional release oral suspension (clinical drug) |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 80 mg/mL oral suspension |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 80 mg/mL oral suspension |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir (as aciclovir sodium) 25 milligram/1 milliliter conventional release solution for injection (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 1.2 g prolonged-release oral tablet |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 1.2 g prolonged-release oral tablet |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir (as aciclovir sodium) 250 milligram/1 vial powder for conventional release solution for infusion (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir 200 milligram/1 each tablet for conventional release oral suspension (clinical drug) |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir 200 milligram/1 each tablet for conventional release oral suspension (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir 400 milligram/1 each tablet for conventional release oral suspension (clinical drug) |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir 400 milligram/1 each tablet for conventional release oral suspension (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir 800 milligram/1 each tablet for conventional release oral suspension (clinical drug) |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir 800 milligram/1 each tablet for conventional release oral suspension (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir (as aciclovir sodium) 25 milligram/1 milliliter conventional release solution for infusion and/or injection (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing precisely aciclovir (as aciclovir sodium) 250 milligram/1 vial powder for conventional release solution for infusion and/or injection (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 50 mg/g and hydrocortisone 10 mg/g cutaneous cream |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 50 mg/g and hydrocortisone 10 mg/g cutaneous cream |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir and hydrocortisone only product in cutaneous dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir and hydrocortisone only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing aciclovir and hydrocortisone in cutaneous dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 50 mg/g cutaneous stick |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Aciclovir 50 mg/g cutaneous stick |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |
Product containing aciclovir and hydrocortisone (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Aciclovir |
Inferred relationship |
Some |
1 |