| Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
| surdose de docusate d'intention indéterminée |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Irritant cathartic overdose |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
1 |
| Castor oil overdose |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Accidental castor oil overdose |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Intentional castor oil overdose |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Castor oil overdose of undetermined intent |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Phenolphthalein overdose |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Accidental phenolphthalein overdose |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Intentional phenolphthalein overdose |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| surdose de phénolphtaléine d'intention indéterminée |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Overdose of emollient cathartic drug |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Methylcellulose [antidiarrheal] |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Sterculia [antidiarrheal] |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Bulk forming drugs [gastro-intestinal use] |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Methylcellulose [gastro-intestinal bulk laxative] |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Methylcellulose-450 500 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Sterculia [bulk laxative] |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Frangula 80 microgram/mg and Sterculia gum 620 microgram/mg oral granules |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Sterculia 62% granules |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Sterculia granules 7g |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Stimulant laxatives |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Fig |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Figs compound elixir |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Product containing sodium picosulfate (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Sodium picosulfate 5mg/5mL liquid |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Sodium picosulfate 10mg/sachet oral powder |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Fecal softening laxatives |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Magnesium hydroxide [laxative] |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Magnesium sulfate powder |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Magnesium sulfate 4g/10mL mixture |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Magnesium sulfate BP crystals |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Polyethylene glycol electrolyte |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Polyethylene glycol electrolyte powder |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Magnesium citrate 17.7g/sachet powder |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Product containing lactitol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Rectally given laxatives |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Glycerol 2g child suppository |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Glycerol 1g infant suppository |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Glycerol 4g adult suppository |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Phosphates Formula B bottle enema BP |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Arachis oil retention enema |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Phosphates Formula B long tube enema BP |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Other laxatives |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Rhubarb compound mixture |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Rhubarb+soda ammoniated mixture |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Methylcellulose [appetite suppressants] |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Sterculia [appetite suppressants] |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Magnesium hydroxide mixture BP |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Compound sodium citrate enema |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Phosphate enema |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Glycerol suppository |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Product containing precisely magnesium hydroxide 83 milligram/1 milliliter conventional release oral suspension (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Product containing Sterculia gum (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Product containing macrogol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Product containing magnesium sulfate (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Polyethylene glycol 3350 100% powder |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Docusate sodium (substance) |
Is a |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Diphenylmethane laxative |
Is a |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Anthraquinone laxative (substance) |
Is a |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Bran (substance) |
Is a |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Bulk-forming laxative |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Poisoning caused by emollient cathartic |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Product containing magnesium hydroxide (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| agent laxatif |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Saline laxative |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Poisoning by phenolphthalein |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Product containing monobasic sodium phosphate (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Poisoning by castor oil |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Poisoning by dioctyl sulfosuccinate |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Poisoning caused by irritant cathartic |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Mercurous chloride |
Is a |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Fiber |
Is a |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Alverine citrate 5 mg/g and Sterculia gum 620 mg/g oral granules |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Product containing phenolphthalein (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Alverine citrate+sterculia |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Product containing polycarbophil (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Castor oil adverse reaction |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Glycerol adverse reaction |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Choline salicylate+glycerol 20%/12.6% ear drops |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Liquid paraffin+magnesium hydroxide oral emulsion BP |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Adverse reaction to irritant cathartic |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Adverse reaction to fig |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Adverse reaction to phenolphthalein |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Adverse reaction to emollient cathartic |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Adverse reaction to dioctyl sodium sulfosuccinate |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Product containing glycerol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Adverse reaction to irritant cathartics NOS |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Adverse reaction to emollient cathartic NOS |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Adverse reaction to other cathartics, including intestinal atonia drugs |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Adverse reaction to other cathartics including intestinal atonia drugs NOS |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Macrogol |
Is a |
True |
Laxative (substance) |
Inferred relationship |
Some |
|
| Psyllium and/or psyllium derivative (substance) |
Is a |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Calcium polycarbophil (substance) |
Is a |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Sennoside (substance) |
Is a |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Barley malt extract (substance) |
Is a |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Product containing yellow phenolphthalein (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Product containing aluminium hydroxide and magnesium hydroxide and simeticone (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Glycerol |
Is a |
True |
Laxative (substance) |
Inferred relationship |
Some |
|
| Adverse reaction caused by figs compound laxative |
Causative agent (attribute) |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Phenolphthalein |
Is a |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
| Figs compound elixir |
Is a |
False |
Laxative (substance) |
Inferred relationship |
Some |
|
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