372880004: Timolol (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with receptor antagonist mechanism of action (substance)\Substance with adrenergic receptor antagonist mechanism of action (substance)\Substance with beta adrenergic receptor antagonist mechanism of action (substance)\Timolol (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Autonomic agent (substance)\Substance with beta adrenergic receptor antagonist mechanism of action (substance)\Timolol (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Cardiovascular agent (substance)\Hypotensive agent (substance)\Substance with beta adrenergic receptor antagonist mechanism of action (substance)\Timolol (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amine and/or amine derivative\Amine\Amino alcohol\Alkanolamine (substance)\Propanolamine (substance)\Timolol (substance)

\Organic compound\Organic nitrogen compound\Amine and/or amine derivative\Amine\Amino alcohol\Alkanolamine (substance)\Propanolamine (substance)\Timolol (substance)
\Organic compound\Substance with alcohol structure (substance)\Amino alcohol\Alkanolamine (substance)\Propanolamine (substance)\Timolol (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Timolol (substance)	Is a	Non-selective beta-blocking agent	false	Inferred relationship	Some
Timolol (substance)	Is a	agent antiglaucome	false	Inferred relationship	Some
Timolol (substance)	Is a	Propanolamine (substance)	true	Inferred relationship	Some
Timolol (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Beta adrenergic receptor antagonist (disposition)	true	Inferred relationship	Some
Timolol (substance)	Is a	Substance with beta adrenergic receptor antagonist mechanism of action (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Timolol maleate	Is a	False	Timolol (substance)	Inferred relationship	Some
Timolol measurement	Component	True	Timolol (substance)	Inferred relationship	Some	1
Timolol adverse reaction	Causative agent (attribute)	True	Timolol (substance)	Inferred relationship	Some	1
Allergy to timolol (finding)	Causative agent (attribute)	False	Timolol (substance)	Inferred relationship	Some
Product containing precisely amiloride hydrochloride 2.5 milligram and hydrochlorothiazide 25 milligram and timolol maleate 10 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Bendroflumethiazide 2.5 mg and timolol maleate 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Timolol 0.25% liquid eye gel	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Timolol 0.5% liquid eye gel	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Timolol (as timolol maleate) 2.5 mg/mL eye drops	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Product containing precisely timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye drops (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Product containing dorzolamide and timolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Dorzolamide (as dorzolamide hydrochloride) 20 mg/mL and timolol (as timolol maleate) 5 mg/mL eye drops	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Timolol maleate+diuretic	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Product containing timolol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Timolol eye drops	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Topical form timolol	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Timolol 0.25% ophthalmic solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Timolol 0.5% ophthalmic solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Hydrochlorothiazide + timolol maleate 25mg/10mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Product containing latanoprost and timolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Latanoprost+timolol 0.005%/0.5% eye drops	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Timolol 0.1% liquid eye gel	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Product containing timolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Timolol maleate+bendroflumethiazide	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Product containing amiloride and hydrochlorothiazide and timolol maleate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Timolol 0.5% eye drops preservative free	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Timolol (as timolol maleate) 2.5 mg/mL eye drops	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Product containing precisely timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye drops (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Timolol 0.25% metered dose eye drops	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Timolol 0.1% liquid eye gel	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Product containing precisely latanoprost 50 microgram/1 milliliter and timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye drops (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Timolol maleate 0.5% gel forming ophthalmic solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Timolol maleate 0.25% gel forming ophthalmic solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Product containing brimonidine and timolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	2
Brimonidine 0.2%/timolol 0.5% eye drops	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Product containing bendroflumethiazide and timolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing timolol in ophthalmic dosage form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol (substance)	Inferred relationship	Some
Product containing timolol and travoprost (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	2
Product containing bimatoprost and timolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	2
Allergy to timolol (finding)	Causative agent (attribute)	True	Timolol (substance)	Inferred relationship	Some	1
Timolol maleate	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Timolol (substance)	Inferred relationship	Some
Bendroflumethiazide- and timolol-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing amiloride and hydrochlorothiazide and timolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Amiloride- and hydrochlorothiazide- and timolol-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Timolol (as timolol maleate) 1 mg/mL eye gel	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol (substance)	Inferred relationship	Some	1
Timolol (as timolol maleate) 2.5 mg/mL eye gel	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing precisely timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye gel (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol (substance)	Inferred relationship	Some	1
Timolol (as timolol maleate) 2.5 mg/mL eye drops	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing precisely latanoprost 50 microgram/1 milliliter and timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye drops (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing precisely timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye drops (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol (substance)	Inferred relationship	Some	1
Dorzolamide (as dorzolamide hydrochloride) 20 mg/mL and timolol (as timolol maleate) 5 mg/mL eye drops	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol (substance)	Inferred relationship	Some	1
Timolol-containing product in ocular dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Hydrochlorothiazide- and timolol-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Latanoprost- and timolol-containing product in ocular dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing dorzolamide and timolol in ocular dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Hydrochlorothiazide- and timolol-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Bimatoprost and timolol only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	2
Amiloride and hydrochlorothiazide and timolol only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Brimonidine and timolol only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	2
Product containing only bendroflumethiazide and timolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing only dorzolamide and timolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing only hydrochlorothiazide and timolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing only timolol and travoprost (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	2
Product containing only timolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing only latanoprost and timolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Dorzolamide and timolol only product in ocular dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Timolol only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Latanoprost and timolol only product in ocular dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Hydrochlorothiazide and timolol only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing only timolol in ocular dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing only bendroflumethiazide and timolol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Amiloride and hydrochlorothiazide and timolol only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing precisely timolol (as timolol maleate) 2.5 milligram/1 milliliter conventional release eye solution (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Timolol (substance)	Inferred relationship	Some	1
Product containing precisely timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye solution (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Timolol (substance)	Inferred relationship	Some	1
Product containing brimonidine and timolol in ocular dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	2
Brimonidine and timolol only product in ocular dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	2
Product containing precisely brimonidine tartrate 2 milligram/1 milliliter and timolol 5 milligram/1 milliliter conventional release eye solution (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing precisely brimonidine tartrate 2 milligram/1 milliliter and timolol 5 milligram/1 milliliter conventional release eye solution (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol (substance)	Inferred relationship	Some	1
Timolol and travoprost only product in ocular dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	2
Timolol- and travoprost-containing product in ocular dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	2
Product containing precisely timolol (as timolol maleate) 5 milligram/1 milliliter and travoprost 40 microgram/1 milliliter conventional release eye drops (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol (substance)	Inferred relationship	Some	2
Product containing bimatoprost and timolol in ocular dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	2
Product containing only bimatoprost and timolol in ocular dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	2
Bimatoprost 300 microgram/mL and timolol (as timolol maleate) 5 mg/mL eye drops	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol (substance)	Inferred relationship	Some	2
Brinzolamide- and timolol-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing brinzolamide and timolol in ocular dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Brinzolamide and timolol only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing only brinzolamide and timolol in ocular dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Brinzolamide 10 mg/mL and timolol (as timolol maleate) 5 mg/mL eye drops suspension	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing precisely tafluprost 15 microgram/1 milliliter and timolol (as timolol maleate) 5 milligram/1 milliliter conventional release solution for eye drops (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing tafluprost and timolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing only tafluprost and timolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Tafluprost- and timolol-containing product in ocular dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1
Product containing only tafluprost and timolol in ocular dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Timolol (substance)	Inferred relationship	Some	1

Reference Sets

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Id	Description	Lang	Type	Status	Case?	Module
1198175017	Timolol (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1211398018	Timolol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
55211000195110	timololo	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
845941000172111	timolol	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
69771000195115	Timolol	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module