373225007: Substance with serotonin re-uptake inhibitor mechanism of action (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with cellular transport inhibitor mechanism of action (substance)\Selective serotonin re-uptake inhibitor

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Central nervous system agent (substance)\Psychoactive substance (substance)\Psychotropic agent (substance)\Selective serotonin re-uptake inhibitor

Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2018. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Selective serotonin re-uptake inhibitor	Is a	Antidepressant (substance)	false	Inferred relationship	Some
Selective serotonin re-uptake inhibitor	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Serotonin reuptake inhibitor (disposition)	true	Inferred relationship	Some
Selective serotonin re-uptake inhibitor	Is a	Substance categorized by disposition	false	Inferred relationship	Some
Selective serotonin re-uptake inhibitor	Is a	Psychotropic agent (substance)	true	Inferred relationship	Some
Selective serotonin re-uptake inhibitor	Is a	Substance with cellular transport inhibitor mechanism of action (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Paroxetine (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Citalopram (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Fluoxetine (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Fluvoxamine (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Selective serotonin re-uptake inhibitor poisoning	Causative agent (attribute)	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some	1
Sertraline poisoning	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Accidental sertraline poisoning	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Intentional sertraline poisoning	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
intoxication par la sertraline d'intention indéterminée	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Nefazodone poisoning	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Accidental nefazodone poisoning	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Intentional nefazodone poisoning	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Nefazodone poisoning of undetermined intent	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Selective serotonin re-uptake inhibitor adverse reaction	Causative agent (attribute)	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some	1
Sertraline adverse reaction (disorder)	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Nefazodone adverse reaction	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Allergy to selective serotonin re-uptake inhibitor (finding)	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Allergy to sertraline	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Allergy to nefazodone	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Selective serotonin re-uptake inhibitor overdose	Causative agent (attribute)	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some	1
Sertraline overdose	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Accidental sertraline overdose	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Intentional sertraline overdose	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
surdose de sertraline d'intention indéterminée	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Nefazodone overdose	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Accidental nefazodone overdose	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Intentional nefazodone overdose (disorder)	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Nefazodone overdose of undetermined intent	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Product containing sertraline (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Product containing precisely sertraline 50 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Product containing precisely sertraline 100 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Product containing selective serotonin re-uptake inhibitor (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some	1
Sertraline hydrochloride 20mg/mL	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Sertraline hydrochloride 25mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Product containing escitalopram (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Escitalopram 10mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Escitalopram (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Sertraline hydrochloride	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Duloxetine (substance)	Is a	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Zimeldine	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Norfluoxetine	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Desmethylsertraline	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Venlafaxine (substance)	Is a	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Nefazodone (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Sertraline (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Desvenlafaxine (substance)	Is a	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Milnacipran	Is a	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Allergy to selective serotonin re-uptake inhibitor (finding)	Causative agent (attribute)	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some	1
Dapoxetine (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
A characteristic selective serotonin reuptake inhibitor (SSRI) discontinuation syndrome is usually mild, commences within 1 week of stopping treatment, resolves spontaneously within 3 weeks, and consists of diverse physical and psychological symptoms, the commonest being dizziness, nausea, lethargy and headache. SSRI reinstatement leads to resolution within 48 hours.	Causative agent (attribute)	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some	1
Nefazodone hydrochloride	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Citalopram hydrobromide (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Fluvoxamine maleate	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Venlafaxine hydrochloride	Is a	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Sertraline hydrochloride	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Fluoxetine hydrochloride	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Citalopram hydrochloride (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Paroxetine hydrochloride	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Paroxetine mesilate	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Duloxetine hydrochloride (substance)	Is a	False	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Escitalopram oxalate (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Dapoxetine hydrochloride (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Clopenthixol (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Zuclopenthixol (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Zuclopenthixol dihydrochloride (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Zuclopenthixol acetate (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Zuclopenthixol decanoate (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Paroxetine hydrochloride hemihydrate (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Substance with norepinephrine reuptake inhibitor and serotonin reuptake inhibitor mechanism of action (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Vilazodone (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Vilazodone hydrochloride	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Selective serotonin re-uptake inhibitor dependence	Causative agent (attribute)	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some	1
Paroxetine hydrochloride anhydrous (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some
Characterised by persistent sexual side effects that continue after discontinuing selective serotonin re-uptake inhibitors (SSRIs), a class of antidepressants. Symptoms may include reduced libido, erectile dysfunction, anorgasmia (inability to achieve orgasm), genital numbness, and other sexual dysfunctions. These symptoms can last for weeks, months, or even years after stopping the medication.	Causative agent (attribute)	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some	2
Paroxetine hydrochloride acetone solvate (substance)	Is a	True	Selective serotonin re-uptake inhibitor	Inferred relationship	Some

Reference Sets

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Id	Description	Lang	Type	Status	Case?	Module
1211718015	Selective serotonin re-uptake inhibitor	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1229187011	SSRI - Selective serotonin re-uptake inhibitor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
3638480011	Substance with serotonin re-uptake inhibitor mechanism of action (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3638481010	Substance with serotonin re-uptake inhibitor mechanism of action	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
7444811000241117	IRS - inhibiteur de la recapture de la sérotonine	fr	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
7444821000241112	inhibiteur de la recapture de la sérotonine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module