373345002: Tamoxifen (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with receptor antagonist mechanism of action (substance)\Antihormone\Estrogen receptor antagonist\Tamoxifen (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antihormone\Estrogen receptor antagonist\Tamoxifen (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Hydride (substance)\Organic hydride (substance)\Tamoxifen (substance)

\Organic compound\Organic hydride (substance)\Tamoxifen (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Tamoxifen (substance)	Is a	Estrogen receptor antagonist	true	Inferred relationship	Some
Tamoxifen (substance)	Is a	classe d'allergènes	false	Inferred relationship	Some
Tamoxifen (substance)	Is a	allergène médicamenteux	false	Inferred relationship	Some
Tamoxifen (substance)	Is a	Selective estrogen receptor modulator (substance)	false	Inferred relationship	Some
Tamoxifen (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Estrogen receptor antagonist (disposition)	true	Inferred relationship	Some
Tamoxifen (substance)	Is a	Organic hydride (substance)	true	Inferred relationship	Some
Tamoxifen (substance)	Is a	A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.	false	Inferred relationship	Some
Tamoxifen (substance)	Is a	Antihormone	false	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Tamoxifen citrate	Is a	False	Tamoxifen (substance)	Inferred relationship	Some
Tamoxifen measurement	Component	True	Tamoxifen (substance)	Inferred relationship	Some	1
Tamoxifen poisoning	Causative agent (attribute)	True	Tamoxifen (substance)	Inferred relationship	Some	1
Accidental tamoxifen poisoning	Causative agent (attribute)	False	Tamoxifen (substance)	Inferred relationship	Some
Intentional tamoxifen poisoning	Causative agent (attribute)	False	Tamoxifen (substance)	Inferred relationship	Some
intoxication par le tamoxifène d'intention indéterminée	Causative agent (attribute)	False	Tamoxifen (substance)	Inferred relationship	Some	1
Tamoxifen adverse reaction	Causative agent (attribute)	True	Tamoxifen (substance)	Inferred relationship	Some	1
Allergy to tamoxifen (finding)	Causative agent (attribute)	False	Tamoxifen (substance)	Inferred relationship	Some
Tamoxifen overdose	Causative agent (attribute)	True	Tamoxifen (substance)	Inferred relationship	Some	1
Accidental tamoxifen overdose (disorder)	Causative agent (attribute)	True	Tamoxifen (substance)	Inferred relationship	Some	1
Intentional tamoxifen overdose	Causative agent (attribute)	True	Tamoxifen (substance)	Inferred relationship	Some	1
surdose de tamoxifène d'intention indéterminée	Causative agent (attribute)	False	Tamoxifen (substance)	Inferred relationship	Some	1
Tamoxifen retinopathy	Causative agent (attribute)	False	Tamoxifen (substance)	Inferred relationship	Some
Product containing precisely tamoxifen 20 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tamoxifen (substance)	Inferred relationship	Some
Tamoxifen 10mg/5mL s/f oral solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tamoxifen (substance)	Inferred relationship	Some
Product containing precisely tamoxifen 40 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tamoxifen (substance)	Inferred relationship	Some
Product containing tamoxifen (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tamoxifen (substance)	Inferred relationship	Some	1
Product containing precisely tamoxifen 10 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tamoxifen (substance)	Inferred relationship	Some
Accidental tamoxifen poisoning	Causative agent (attribute)	True	Tamoxifen (substance)	Inferred relationship	Some	1
Intentional tamoxifen poisoning	Causative agent (attribute)	True	Tamoxifen (substance)	Inferred relationship	Some	1
Allergy to tamoxifen (finding)	Causative agent (attribute)	True	Tamoxifen (substance)	Inferred relationship	Some	1
Tamoxifen-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tamoxifen (substance)	Inferred relationship	Some	1
Tamoxifen therapy (procedure)	Direct substance	True	Tamoxifen (substance)	Inferred relationship	Some	2
Product containing precisely tamoxifen 10 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tamoxifen (substance)	Inferred relationship	Some	1
Product containing precisely tamoxifen 10 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Tamoxifen (substance)	Inferred relationship	Some	1
Product containing precisely tamoxifen 20 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tamoxifen (substance)	Inferred relationship	Some	1
Product containing precisely tamoxifen 20 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Tamoxifen (substance)	Inferred relationship	Some	1
Product containing precisely tamoxifen 40 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tamoxifen (substance)	Inferred relationship	Some	1
Product containing precisely tamoxifen 40 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Tamoxifen (substance)	Inferred relationship	Some	1
Product containing precisely tamoxifen 20 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Tamoxifen (substance)	Inferred relationship	Some	1
Product containing precisely tamoxifen 10 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Tamoxifen (substance)	Inferred relationship	Some	1
Product containing precisely tamoxifen 40 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Tamoxifen (substance)	Inferred relationship	Some	1
Tamoxifen (as tamoxifen citrate) 2 mg/mL oral solution	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tamoxifen (substance)	Inferred relationship	Some	1
Tamoxifen citrate	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Tamoxifen (substance)	Inferred relationship	Some
Tamoxifen only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tamoxifen (substance)	Inferred relationship	Some	1
Product containing only tamoxifen in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tamoxifen (substance)	Inferred relationship	Some	1
Product containing precisely tamoxifen (as tamoxifen citrate) 10 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tamoxifen (substance)	Inferred relationship	Some	1
Product containing precisely tamoxifen (as tamoxifen citrate) 20 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tamoxifen (substance)	Inferred relationship	Some	1
Product containing precisely tamoxifen (as tamoxifen citrate) 40 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tamoxifen (substance)	Inferred relationship	Some	1
Tamoxifen retinopathy	Causative agent (attribute)	True	Tamoxifen (substance)	Inferred relationship	Some	1
Retinopathy of right eye caused by tamoxifen (disorder)	Causative agent (attribute)	True	Tamoxifen (substance)	Inferred relationship	Some	1
Retinopathy of left eye caused by tamoxifen (disorder)	Causative agent (attribute)	True	Tamoxifen (substance)	Inferred relationship	Some	1
Hot flash caused by tamoxifen (disorder)	Causative agent (attribute)	True	Tamoxifen (substance)	Inferred relationship	Some	1

Reference Sets

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Id	Description	Lang	Type	Status	Case?	Module
1198643019	Tamoxifen (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1211831016	Tamoxifen	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
49121000195114	tamoxifene	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
843571000172112	tamoxifène	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
63251000195119	Tamoxifen	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module