373542000: Methyldopa (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Receptor agonist\Adrenergic receptor agonist\Alpha adrenergic receptor agonist\Alpha-2 adrenergic receptor agonist\Substance with central alpha-2 adrenergic receptor agonist mechanism of action (substance)\Methyldopa (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Autonomic agent (substance)\Sympathomimetic agent (substance)\Adrenergic receptor agonist\Alpha adrenergic receptor agonist\Alpha-2 adrenergic receptor agonist\Substance with central alpha-2 adrenergic receptor agonist mechanism of action (substance)\Methyldopa (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amine and/or amine derivative\Methyldopa (substance)

\Organic compound\Organic nitrogen compound\Amine and/or amine derivative\Methyldopa (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Methyldopa (substance)	Is a	Alpha-2 adrenergic receptor agonist	false	Inferred relationship	Some
Methyldopa (substance)	Is a	Substance with central alpha adrenergic receptor agonist mechanism of action	false	Inferred relationship	Some
Methyldopa (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Alpha-2 adrenergic receptor agonist (disposition)	false	Inferred relationship	Some
Methyldopa (substance)	Is a	Alpha amino acid	false	Inferred relationship	Some
Methyldopa (substance)	Is a	Amine and/or amine derivative	true	Inferred relationship	Some
Methyldopa (substance)	Is a	Substance with central alpha-2 adrenergic receptor agonist mechanism of action (substance)	true	Inferred relationship	Some
Methyldopa (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Central alpha-2 adrenergic receptor agonist	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Methyldopate hydrochloride	Is a	False	Methyldopa (substance)	Inferred relationship	Some
Methyldopa measurement	Component	True	Methyldopa (substance)	Inferred relationship	Some	1
Methyldopa adverse reaction	Causative agent (attribute)	True	Methyldopa (substance)	Inferred relationship	Some	1
Methyldopa and diuretic adverse reaction	Causative agent (attribute)	False	Methyldopa (substance)	Inferred relationship	Some	2
Allergy to methyldopa (finding)	Causative agent (attribute)	False	Methyldopa (substance)	Inferred relationship	Some
Allergy to methyldopa and diuretic	Causative agent (attribute)	False	Methyldopa (substance)	Inferred relationship	Some
Methyldopa 125 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some
Methyldopa 250 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some
Methyldopa 500 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some
Methyldopa 250 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some
Methyldopa+diuretic	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some
Chlorothiazide 250 mg and methyldopa 250 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some
Hydrochlorothiazide + methyldopa 15mg/250mg	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some
Hydrochlorothiazide 15 mg and methyldopa 250 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some
Hydrochlorothiazide 25 mg and methyldopa 250 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some
Hydrochlorothiazide 30 mg and methyldopa 500 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some
Hydrochlorothiazide 50 mg and methyldopa 500 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some
Product containing methyldopa (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Methyldopa (substance)	Inferred relationship	Some	1
Product containing chlorothiazide and methyldopa (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Methyldopa (substance)	Inferred relationship	Some	2
Product containing hydrochlorothiazide and methyldopa (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Methyldopa (substance)	Inferred relationship	Some	1
Allergy to methyldopa (finding)	Causative agent (attribute)	True	Methyldopa (substance)	Inferred relationship	Some	1
Allergy to methyldopa and diuretic	Causative agent (attribute)	False	Methyldopa (substance)	Inferred relationship	Some	1
Product containing methyldopa in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Methyldopa (substance)	Inferred relationship	Some	1
Cirrhosis of liver caused by methyldopa (disorder)	Causative agent (attribute)	False	Methyldopa (substance)	Inferred relationship	Some	3
Methyldopa 125 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some	1
Methyldopa 125 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Methyldopa (substance)	Inferred relationship	Some	1
Methyldopa 250 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some	1
Methyldopa 250 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Methyldopa (substance)	Inferred relationship	Some	1
Methyldopa 500 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some	1
Methyldopa 500 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Methyldopa (substance)	Inferred relationship	Some	1
Methyldopa 250 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some	1
Methyldopa 250 mg oral capsule	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Methyldopa (substance)	Inferred relationship	Some	1
Chlorothiazide 250 mg and methyldopa 250 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some	2
Chlorothiazide 250 mg and methyldopa 250 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Methyldopa (substance)	Inferred relationship	Some	2
Hydrochlorothiazide 15 mg and methyldopa 250 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some	1
Hydrochlorothiazide 15 mg and methyldopa 250 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Methyldopa (substance)	Inferred relationship	Some	1
Hydrochlorothiazide 25 mg and methyldopa 250 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Methyldopa (substance)	Inferred relationship	Some	2
Hydrochlorothiazide 50 mg and methyldopa 500 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some	2
Hydrochlorothiazide 50 mg and methyldopa 500 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Methyldopa (substance)	Inferred relationship	Some	2
Hydrochlorothiazide 15 mg and methyldopa 250 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Methyldopa (substance)	Inferred relationship	Some	2
Hydrochlorothiazide 30 mg and methyldopa 500 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some	2
Hydrochlorothiazide 30 mg and methyldopa 500 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Methyldopa (substance)	Inferred relationship	Some	2
Hydrochlorothiazide 50 mg and methyldopa 500 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Methyldopa (substance)	Inferred relationship	Some	1
Hydrochlorothiazide 25 mg and methyldopa 250 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Methyldopa (substance)	Inferred relationship	Some	1
Hydrochlorothiazide 25 mg and methyldopa 250 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Methyldopa (substance)	Inferred relationship	Some	1
Chlorothiazide 250 mg and methyldopa 250 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Methyldopa (substance)	Inferred relationship	Some	2
Methyldopa 125 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Methyldopa (substance)	Inferred relationship	Some	1
Methyldopa 250 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Methyldopa (substance)	Inferred relationship	Some	1
Methyldopa 500 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Methyldopa (substance)	Inferred relationship	Some	1
Methyldopa 250 mg oral capsule	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Methyldopa (substance)	Inferred relationship	Some	1
Product containing chlorothiazide and methyldopa in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Methyldopa (substance)	Inferred relationship	Some	2
Hydrochlorothiazide 50 mg and methyldopa 500 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Methyldopa (substance)	Inferred relationship	Some	1
Hydrochlorothiazide 25 mg and methyldopa 250 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Methyldopa (substance)	Inferred relationship	Some	2
Hydrochlorothiazide 30 mg and methyldopa 500 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Methyldopa (substance)	Inferred relationship	Some	2
Hydrochlorothiazide 15 mg and methyldopa 250 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Methyldopa (substance)	Inferred relationship	Some	2
Product containing hydrochlorothiazide and methyldopa in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Methyldopa (substance)	Inferred relationship	Some	1
Chlorothiazide and methyldopa only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Methyldopa (substance)	Inferred relationship	Some	2
Product containing only hydrochlorothiazide and methyldopa (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Methyldopa (substance)	Inferred relationship	Some	1
Product containing only methyldopa (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Methyldopa (substance)	Inferred relationship	Some	1
Product containing only methyldopa in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Methyldopa (substance)	Inferred relationship	Some	1
Chlorothiazide and methyldopa only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Methyldopa (substance)	Inferred relationship	Some	2
Product containing only hydrochlorothiazide and methyldopa in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Methyldopa (substance)	Inferred relationship	Some	1
Methyldopa anhydrous	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Methyldopa (substance)	Inferred relationship	Some
Methyldopate (substance)	Is a	False	Methyldopa (substance)	Inferred relationship	Some
Cirrhosis of liver caused by methyldopa (disorder)	Causative agent (attribute)	True	Methyldopa (substance)	Inferred relationship	Some	1
Cirrhosis of liver caused by methyldopa (disorder)	Causative agent (attribute)	True	Methyldopa (substance)	Inferred relationship	Some	2
Hydrochlorothiazide 15 mg and methyldopa 250 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Methyldopa (substance)	Inferred relationship	Some	1
Hydrochlorothiazide 25 mg and methyldopa 250 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Methyldopa (substance)	Inferred relationship	Some	1
Hydrochlorothiazide 30 mg and methyldopa 500 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Methyldopa (substance)	Inferred relationship	Some	1
Hydrochlorothiazide 30 mg and methyldopa 500 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Methyldopa (substance)	Inferred relationship	Some	1
Methyldopa sesquihydrate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Methyldopa (substance)	Inferred relationship	Some
Methyldopate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Methyldopa (substance)	Inferred relationship	Some

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1198842010	Methyldopa (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1212009011	Methyldopa	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
364131000195117	metildopa	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
824871000172111	méthyldopa	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
2359191000195112	Methyldopa	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module