385556006: Tenofovir disoproxil fumarate (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Reverse transcriptase inhibitor\Tenofovir disoproxil fumarate (substance)
\Substance categorized by disposition\Substance with antiviral mechanism of action (substance)\Substance with antiretroviral mechanism of action (substance)\Reverse transcriptase inhibitor\Tenofovir disoproxil fumarate (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Anti-infective agent (substance)\Substance with antiviral mechanism of action (substance)\Substance with antiretroviral mechanism of action (substance)\Reverse transcriptase inhibitor\Tenofovir disoproxil fumarate (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\...

\Organic acid and/or organic acid derivative\Carboxylic acid and/or carboxylic acid derivative (substance)\Carboxylic ester (substance)\Tenofovir disoproxil fumarate (substance)

\Ester\Carboxylic ester (substance)\Tenofovir disoproxil fumarate (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

1459735016 Tenofovir disoproxil fumarate (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

1479761018 Tenofovir disoproxil fumarate en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

30261000188112 ténofovir disoproxil fumarate fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

844251000172117 fumarate de ténofovir disoproxil fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Tenofovir disoproxil fumarate (substance)	Is a	Reverse transcriptase inhibitor	true	Inferred relationship	Some
Tenofovir disoproxil fumarate (substance)	Is a	Tenofovir (substance)	false	Inferred relationship	Some
Tenofovir disoproxil fumarate (substance)	Is a	Tenofovir disoproxil (substance)	false	Inferred relationship	Some
Tenofovir disoproxil fumarate (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Reverse transcriptase inhibitor (disposition)	true	Inferred relationship	Some
Tenofovir disoproxil fumarate (substance)	Is a	Transferase inhibitor	false	Inferred relationship	Some
Tenofovir disoproxil fumarate (substance)	Is a	Carboxylic ester (substance)	true	Inferred relationship	Some
Tenofovir disoproxil fumarate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	Tenofovir disoproxil (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Tenofovir 300mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some
Product containing tenofovir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some
Tenofovir disoproxil 245mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some
Product containing precisely tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some
Tenofovir disoproxil 245mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some
Product containing emtricitabine and tenofovir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some
Product containing precisely emtricitabine 200 milligram and tenofovir disoproxil fumarate 136 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some
Product containing efavirenz and emtricitabine and tenofovir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some
Efavirenz 600 mg and emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some
Product containing precisely tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some
Product containing precisely tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	1
Product containing precisely emtricitabine 200 milligram and tenofovir disoproxil fumarate 136 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	2
Product containing precisely emtricitabine 200 milligram and tenofovir disoproxil fumarate 136 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	2
Product containing precisely emtricitabine 200 milligram and tenofovir disoproxil fumarate 136 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	1
Efavirenz 600 mg and emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	1
Efavirenz 600 mg and emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	1
Efavirenz 600 mg and emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	1
Product containing precisely tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	1
Product containing precisely emtricitabine 200 milligram and tenofovir disoproxil fumarate 136 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	1
Product containing precisely efavirenz 600 milligram and lamivudine 300 milligram and tenofovir disoproxil fumarate 300 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	1
Product containing precisely efavirenz 600 milligram and lamivudine 300 milligram and tenofovir disoproxil fumarate 300 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	1
Product containing precisely tenofovir disoproxil fumarate 150 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	1
Product containing precisely tenofovir disoproxil fumarate 150 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	1
Product containing precisely dolutegravir (as dolutegravir sodium) 50 milligram and lamivudine 300 milligram and tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	2
Product containing precisely efavirenz 400 milligram and lamivudine 300 milligram and tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	3
Emtricitabine 200 mg and tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	2
Product containing precisely lamivudine 300 milligram and tenofovir disoproxil fumarate 300 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	1
Product containing precisely lamivudine 300 milligram and tenofovir disoproxil fumarate 300 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	1
Doravirine 100 mg and lamivudine 300 mg and tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	2
Emtricitabine 200 mg and rilpivirine (as rilpivirine hydrochloride) 25 mg and tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Some	2

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1459735016	Tenofovir disoproxil fumarate (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1479761018	Tenofovir disoproxil fumarate	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
30261000188112	ténofovir disoproxil fumarate	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
844251000172117	fumarate de ténofovir disoproxil	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module