386855006: Donepezil (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Acetylcholinesterase inhibitor\Centrally acting acetylcholinesterase inhibitor\Donepezil (substance)
\Substance categorized by disposition\Receptor agonist\Substance with sigma-1 receptor agonist mechanism of action (substance)\Donepezil (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Autonomic agent (substance)\Parasympathomimetic agent (substance)\Acetylcholinesterase inhibitor\Centrally acting acetylcholinesterase inhibitor\Donepezil (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Central nervous system agent (substance)\Donepezil (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative (substance)\Donepezil (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative (substance)\Donepezil (substance)
\Organic compound\Organic nitrogen compound\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative (substance)\Donepezil (substance)
\Organic compound\Ketone\Cyclic ketone\Donepezil (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Donepezil (substance)	Is a	Substance with cholinesterase inhibitor mechanism of action	false	Inferred relationship	Some
Donepezil (substance)	Is a	classe d'allergènes	false	Inferred relationship	Some
Donepezil (substance)	Is a	allergène médicamenteux	false	Inferred relationship	Some
Donepezil (substance)	Is a	agent antidémence	false	Inferred relationship	Some
Donepezil (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Acetylcholine receptor agonist (disposition)	false	Inferred relationship	Some
Donepezil (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Cholinesterase inhibitor	false	Inferred relationship	Some
Donepezil (substance)	Is a	Parasympathomimetic agent (substance)	false	Inferred relationship	Some
Donepezil (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Donepezil (substance)	Is a	Centrally acting acetylcholinesterase inhibitor	true	Inferred relationship	Some
Donepezil (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Centrally acting acetylcholinesterase inhibitor (disposition)	true	Inferred relationship	Some
Donepezil (substance)	Is a	Piperidine derivative (substance)	true	Inferred relationship	Some
Donepezil (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Donepezil (substance)	Is a	Substance with sigma-1 receptor agonist mechanism of action (substance)	true	Inferred relationship	Some
Donepezil (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Sigma-1 receptor agonist (disposition)	true	Inferred relationship	Some
Donepezil (substance)	Is a	Cyclic ketone	true	Inferred relationship	Some
Donepezil (substance)	Is a	Central nervous system agent (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing donepezil (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Donepezil (substance)	Inferred relationship	Some	1
Donepezil hydrochloride (substance)	Is a	False	Donepezil (substance)	Inferred relationship	Some
Product containing donepezil and memantine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Donepezil (substance)	Inferred relationship	Some	1
Donepezil- and memantine-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Donepezil (substance)	Inferred relationship	Some	1
Donepezil-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Donepezil (substance)	Inferred relationship	Some	1
Donepezil hydrochloride (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Donepezil (substance)	Inferred relationship	Some
Product containing only donepezil (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Donepezil (substance)	Inferred relationship	Some	1
Product containing only donepezil and memantine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Donepezil (substance)	Inferred relationship	Some	1
Product containing only donepezil and memantine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Donepezil (substance)	Inferred relationship	Some	1
Donepezil only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Donepezil (substance)	Inferred relationship	Some	1
Donepezil only product in oromucosal dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Donepezil (substance)	Inferred relationship	Some	1
Product containing donepezil in oromucosal dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Donepezil (substance)	Inferred relationship	Some	1
Donepezil (as donepezil hydrochloride) 5 mg and memantine (as memantine hydrochloride) 10 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Donepezil (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461033019	Donepezil (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1480970011	Donepezil	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
57091000195116	donepezil	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
807121000172119	donépézil	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
72231000195113	Donepezil	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module