386856007: Donepezil hydrochloride (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Acetylcholinesterase inhibitor\Centrally acting acetylcholinesterase inhibitor\Donepezil hydrochloride (substance)
\Substance categorized by disposition\Receptor agonist\Substance with sigma-1 receptor agonist mechanism of action (substance)\Donepezil hydrochloride (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Autonomic agent (substance)\Parasympathomimetic agent (substance)\Acetylcholinesterase inhibitor\Centrally acting acetylcholinesterase inhibitor\Donepezil hydrochloride (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Central nervous system agent (substance)\Donepezil hydrochloride (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative (substance)\Donepezil hydrochloride (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative (substance)\Donepezil hydrochloride (substance)
\Organic compound\Organic nitrogen compound\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative (substance)\Donepezil hydrochloride (substance)
\Organic compound\Ketone\Cyclic ketone\Donepezil hydrochloride (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

1461034013 Donepezil hydrochloride (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

1480971010 Donepezil hydrochloride en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

46141000188116 donépézil chlorhydrate fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

807141000172111 chlorhydrate de donépézil fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Donepezil hydrochloride (substance)	Is a	Donepezil (substance)	false	Inferred relationship	Some
Donepezil hydrochloride (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Acetylcholine receptor agonist (disposition)	false	Inferred relationship	Some
Donepezil hydrochloride (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Cholinesterase inhibitor	false	Inferred relationship	Some
Donepezil hydrochloride (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Centrally acting acetylcholinesterase inhibitor (disposition)	true	Inferred relationship	Some
Donepezil hydrochloride (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	Donepezil (substance)	true	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	allergène médicamenteux	false	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Piperidine derivative (substance)	true	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Centrally acting acetylcholinesterase inhibitor	true	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Parasympathomimetic agent (substance)	false	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Substance with sigma-1 receptor agonist mechanism of action (substance)	true	Inferred relationship	Some
Donepezil hydrochloride (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Sigma-1 receptor agonist (disposition)	true	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Cyclic ketone	true	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Central nervous system agent (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing donepezil hydrochloride	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil hydrochloride 5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil hydrochloride 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil 1mg/mL oral solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil 5mg orally disintegrating tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil 10mg orally disintegrating tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Aricept odt 5mg orally disintegrating tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil hydrochloride 23 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil hydrochloride 5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 5 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 10 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 23 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 23 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride monohydrate (substance)	Is a	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil hydrochloride 10 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 23 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 5 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride monohydrate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Donepezil hydrochloride (substance)	Inferred relationship	Some
Product containing precisely donepezil hydrochloride 10 milligram/1 each conventional release orodispersible tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Product containing precisely donepezil hydrochloride 10 milligram/1 each conventional release orodispersible tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 1 mg/mL oral solution	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 1 mg/mL oral solution	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 5 mg orodispersible tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 5 mg orodispersible tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil (as donepezil hydrochloride) 5 mg and memantine (as memantine hydrochloride) 10 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461034013	Donepezil hydrochloride (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1480971010	Donepezil hydrochloride	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
46141000188116	donépézil chlorhydrate	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
807141000172111	chlorhydrate de donépézil	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module