386874003: Quinapril (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\...

\Substance with renin-angiotensin system inhibitor mechanism of action (substance)\Angiotensin-converting enzyme inhibitor\Quinapril (substance)

\Hydrolase inhibitor\Peptide hydrolase inhibitor\Angiotensin-converting enzyme inhibitor\Quinapril (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Cardiovascular agent (substance)\Hypotensive agent (substance)\Substance with renin-angiotensin system inhibitor mechanism of action (substance)\Angiotensin-converting enzyme inhibitor\Quinapril (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Heterocyclic compound\Isoquinoline (substance)\Quinapril (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Quinapril (substance)	Is a	Angiotensin-converting enzyme inhibitor	true	Inferred relationship	Some
Quinapril (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Angiotensin-converting enzyme inhibitor (disposition)	true	Inferred relationship	Some
Quinapril (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Quinapril (substance)	Is a	Isoquinoline (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing quinapril (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Quinapril (substance)	Inferred relationship	Some	1
Quinapril adverse reaction	Causative agent (attribute)	True	Quinapril (substance)	Inferred relationship	Some	1
Quinapril allergy	Causative agent (attribute)	False	Quinapril (substance)	Inferred relationship	Some
Quinapril hydrochloride (substance)	Is a	False	Quinapril (substance)	Inferred relationship	Some
Product containing precisely hydrochlorothiazide 12.5 milligram and quinapril 10 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Quinapril (substance)	Inferred relationship	Some
Product containing precisely hydrochlorothiazide 12.5 milligram and quinapril 20 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Quinapril (substance)	Inferred relationship	Some
Product containing precisely hydrochlorothiazide 25 milligram and quinapril 20 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Quinapril (substance)	Inferred relationship	Some
Product containing hydrochlorothiazide and quinapril (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Quinapril (substance)	Inferred relationship	Some	1
Non-allergic hypersensitivity to quinapril (finding)	Causative agent (attribute)	False	Quinapril (substance)	Inferred relationship	Some
Non-allergic hypersensitivity to quinapril (finding)	Causative agent (attribute)	False	Quinapril (substance)	Inferred relationship	Some	2
Non-allergic hypersensitivity to quinapril (finding)	Causative agent (attribute)	True	Quinapril (substance)	Inferred relationship	Some	1
Quinapril (as quinapril hydrochloride) 5 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Quinapril (substance)	Inferred relationship	Some	1
Product containing precisely quinapril (as quinapril hydrochloride) 10 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Quinapril (substance)	Inferred relationship	Some	1
Product containing precisely quinapril (as quinapril hydrochloride) 20 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Quinapril (substance)	Inferred relationship	Some	1
Quinapril (as quinapril hydrochloride) 40 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Quinapril (substance)	Inferred relationship	Some	1
Product containing precisely hydrochlorothiazide 12.5 milligram and quinapril 20 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Quinapril (substance)	Inferred relationship	Some	1
Product containing precisely hydrochlorothiazide 12.5 milligram and quinapril 20 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Quinapril (substance)	Inferred relationship	Some	2
Product containing precisely hydrochlorothiazide 12.5 milligram and quinapril 20 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Quinapril (substance)	Inferred relationship	Some	2
Product containing precisely hydrochlorothiazide 25 milligram and quinapril 20 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Quinapril (substance)	Inferred relationship	Some	2
Product containing precisely hydrochlorothiazide 25 milligram and quinapril 20 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Quinapril (substance)	Inferred relationship	Some	2
Product containing precisely hydrochlorothiazide 12.5 milligram and quinapril 10 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Quinapril (substance)	Inferred relationship	Some	1
Product containing precisely hydrochlorothiazide 12.5 milligram and quinapril 10 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Quinapril (substance)	Inferred relationship	Some	1
Quinapril hydrochloride (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Quinapril (substance)	Inferred relationship	Some
Product containing precisely hydrochlorothiazide 12.5 milligram and quinapril 20 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Quinapril (substance)	Inferred relationship	Some	1
Product containing precisely hydrochlorothiazide 12.5 milligram and quinapril 10 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Quinapril (substance)	Inferred relationship	Some	1
Product containing precisely hydrochlorothiazide 25 milligram and quinapril 20 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Quinapril (substance)	Inferred relationship	Some	2
Product containing quinapril in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Quinapril (substance)	Inferred relationship	Some	1
Hydrochlorothiazide- and quinapril-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Quinapril (substance)	Inferred relationship	Some	1
Hydrochlorothiazide and quinapril only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Quinapril (substance)	Inferred relationship	Some	1
Quinapril only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Quinapril (substance)	Inferred relationship	Some	1
Hydrochlorothiazide and quinapril only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Quinapril (substance)	Inferred relationship	Some	1
Quinapril only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Quinapril (substance)	Inferred relationship	Some	1
Hydrochlorothiazide 12.5 mg and quinapril (as quinapril hydrochloride) 10 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Quinapril (substance)	Inferred relationship	Some	1
Product containing precisely hydrochlorothiazide 25 milligram and quinapril 20 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Quinapril (substance)	Inferred relationship	Some	1
Product containing precisely hydrochlorothiazide 25 milligram and quinapril 20 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Quinapril (substance)	Inferred relationship	Some	1
Product containing precisely hydrochlorothiazide 25 milligram and quinapril (as quinapril hydrochloride) 20 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Quinapril (substance)	Inferred relationship	Some	1
Product containing precisely hydrochlorothiazide 12.5 milligram and quinapril (as quinapril hydrochloride) 20 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Quinapril (substance)	Inferred relationship	Some	1

Reference Sets

Description inactivation indicator reference set

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Id	Description	Lang	Type	Status	Case?	Module
1461052013	Quinapril (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1480988015	Quinapril	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
55401000195112	quinapril	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
837011000172117	quinapril	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
70411000195115	Quinapril	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module