386948008: Filgrastim (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Immunomodulator\Immune enhancement agent (substance)\Colony stimulating factor (substance)\Colony-stimulating factor, granulocytic\Recombinant human granulocyte colony stimulating factor (substance)\Filgrastim (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Immune enhancement agent (substance)\Colony stimulating factor (substance)\Colony-stimulating factor, granulocytic\Recombinant human granulocyte colony stimulating factor (substance)\Filgrastim (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Recombinant protein (substance)\Recombinant glycoprotein\Recombinant human granulocyte colony stimulating factor (substance)\Filgrastim (substance)

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Recombinant protein (substance)\Recombinant glycoprotein\Recombinant human granulocyte colony stimulating factor (substance)\Filgrastim (substance)

\Biological substance\Protein and/or protein derivative\Protein\Recombinant protein (substance)\Recombinant glycoprotein\Recombinant human granulocyte colony stimulating factor (substance)\Filgrastim (substance)
\Biological substance\Colony stimulating factor (substance)\Colony-stimulating factor, granulocytic\Recombinant human granulocyte colony stimulating factor (substance)\Filgrastim (substance)
\Biological substance\Polypeptide\Protein\Recombinant protein (substance)\Recombinant glycoprotein\Recombinant human granulocyte colony stimulating factor (substance)\Filgrastim (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Filgrastim (substance)	Is a	Colony stimulating factor (substance)	false	Inferred relationship	Some
Filgrastim (substance)	Is a	Immunomodulator	false	Inferred relationship	Some
Filgrastim (substance)	Is a	Recombinant human granulocyte colony stimulating factor (substance)	true	Inferred relationship	Some
Filgrastim (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	A substance that modifies the immune response or the functioning of the immune system.	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing filgrastim (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Filgrastim (substance)	Inferred relationship	Some	1
Filgrastim adverse reaction	Causative agent (attribute)	True	Filgrastim (substance)	Inferred relationship	Some	1
Allergy to filgrastim (finding)	Causative agent (attribute)	False	Filgrastim (substance)	Inferred relationship	Some
Filgrastim 30million units/mL injection solution 1mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Filgrastim (substance)	Inferred relationship	Some
Filgrastim 48million units/mL injection solution 1.6mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Filgrastim (substance)	Inferred relationship	Some
Filgrastim 600mcg injection solution 1mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Filgrastim (substance)	Inferred relationship	Some
Filgrastim 300mcg/mL solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Filgrastim (substance)	Inferred relationship	Some
Filgrastim 480mcg/1.6mL solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Filgrastim (substance)	Inferred relationship	Some
Filgrastim 30million units/0.5mL prefilled syringe	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Filgrastim (substance)	Inferred relationship	Some
Filgrastim 48million units/0.5mL prefilled syringe	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Filgrastim (substance)	Inferred relationship	Some
Filgrastim 30million units/0.5mL prefilled syringe	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Filgrastim (substance)	Inferred relationship	Some
Filgrastim 48million units/0.5mL prefilled syringe	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Filgrastim (substance)	Inferred relationship	Some
Allergy to filgrastim (finding)	Causative agent (attribute)	True	Filgrastim (substance)	Inferred relationship	Some	1
Filgrastim-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Filgrastim (substance)	Inferred relationship	Some	1
Product containing precisely filgrastim (as pegfilgrastim) 6 milligram/0.6 milliliter conventional release solution for injection syringe	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Filgrastim (substance)	Inferred relationship	Some	1
Filgrastim only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Filgrastim (substance)	Inferred relationship	Some	1
Product containing only filgrastim in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Filgrastim (substance)	Inferred relationship	Some	1
Filgrastim (as pegfilgrastim) 10 mg/mL solution for injection	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Filgrastim (substance)	Inferred relationship	Some	1
Product containing precisely filgrastim 300 microgram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Filgrastim (substance)	Inferred relationship	Some	1
Product containing precisely filgrastim 300 microgram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Filgrastim (substance)	Inferred relationship	Some	1
Pegfilgrastim (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Filgrastim (substance)	Inferred relationship	Some
Lipegfilgrastim (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Filgrastim (substance)	Inferred relationship	Some
Product containing precisely filgrastim 600 microgram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Filgrastim (substance)	Inferred relationship	Some	1
Product containing precisely filgrastim 600 microgram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Filgrastim (substance)	Inferred relationship	Some	1
Filgrastim 960 microgram/mL solution for injection	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Filgrastim (substance)	Inferred relationship	Some	1
Filgrastim 960 microgram/mL solution for injection	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Filgrastim (substance)	Inferred relationship	Some	1
Product containing precisely filgrastim (as lipegfilgrastim) 10 milligram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Filgrastim (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461126016	Filgrastim (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481062013	Filgrastim	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
51831000195118	filgrastim	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
811761000172117	filgrastim	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
1119481000241119	filgrastim recombinant	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
236111000195115	Filgrastim	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
1390551001000115	Filgrastim rekombiniert	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module