387003001: Trastuzumab (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Epidermal growth factor receptor inhibitor\Human epidermal growth factor receptor 2 inhibitor\Trastuzumab (substance)
\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Enzyme inhibitor protein\Trastuzumab (substance)
\Substance categorized by disposition\Immunomodulator\Immunosuppressant (substance)\Trastuzumab (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\...

\Enzyme inhibitor protein\Trastuzumab (substance)

\Antibody\Monoclonal antibody\Trastuzumab (substance)

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\...

\Enzyme inhibitor protein\Trastuzumab (substance)

\Antibody\Monoclonal antibody\Trastuzumab (substance)

\Biological substance\Protein and/or protein derivative\Protein\Enzyme inhibitor protein\Trastuzumab (substance)
\Biological substance\Protein and/or protein derivative\Protein\Antibody\Monoclonal antibody\Trastuzumab (substance)
\Biological substance\Immunologic substance\Antibody\Monoclonal antibody\Trastuzumab (substance)
\Biological substance\Polypeptide\Protein\Enzyme inhibitor protein\Trastuzumab (substance)
\Biological substance\Polypeptide\Protein\Antibody\Monoclonal antibody\Trastuzumab (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Trastuzumab (substance)	Is a	Antineoplastic agent (substance)	false	Inferred relationship	Some
Trastuzumab (substance)	Is a	anticorps monoclonal chimérique souris-humain d'isotype IgG	false	Inferred relationship	Some
Trastuzumab (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Murine-human monoclonal immunoglobulin G antibody	false	Inferred relationship	Some
Trastuzumab (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	A substance that modifies the immune response or the functioning of the immune system.	true	Inferred relationship	Some
Trastuzumab (substance)	Is a	Human epidermal growth factor receptor 2 inhibitor	true	Inferred relationship	Some
Trastuzumab (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Human epidermal growth factor receptor 2 inhibitor	true	Inferred relationship	Some
Trastuzumab (substance)	Is a	Enzyme inhibitor protein	true	Inferred relationship	Some
Trastuzumab (substance)	Is a	Immunosuppressant (substance)	true	Inferred relationship	Some
Trastuzumab (substance)	Is a	Monoclonal antibody	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing trastuzumab (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 150 mg powder for solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Trastuzumab (substance)	Inferred relationship	Some
Trastuzumab 440 mg powder for solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Trastuzumab (substance)	Inferred relationship	Some
Adverse reaction to trastuzumab administered by infusion	Causative agent (attribute)	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab emtansine	Is a	False	Trastuzumab (substance)	Inferred relationship	Some
Product containing trastuzumab in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 150 mg powder for solution for injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 150 mg powder for solution for injection vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing only trastuzumab (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab emtansine	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	False	Trastuzumab (substance)	Inferred relationship	Some
Trastuzumab 440 mg powder for solution for injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 440 mg powder for solution for injection vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab deruxtecan	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	False	Trastuzumab (substance)	Inferred relationship	Some
Product containing precisely trastuzumab 120 milligram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing precisely trastuzumab 120 milligram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing precisely trastuzumab 60 milligram/1 vial powder for conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing precisely trastuzumab 60 milligram/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing precisely trastuzumab 420 milligram/1 vial powder for conventional release solution for infusion (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing precisely trastuzumab 420 milligram/1 vial powder for conventional release solution for infusion (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 60 mg powder for solution for infusion vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 60 mg powder for solution for infusion vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 60 mg powder for solution for infusion and/or injection vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 60 mg powder for solution for infusion and/or injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing precisely pertuzumab 80 milligram/1 milliliter and trastuzumab 40 milligram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing precisely pertuzumab 80 milligram/1 milliliter and trastuzumab 40 milligram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing precisely pertuzumab 60 milligram/1 milliliter and trastuzumab 60 milligram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing precisely pertuzumab 60 milligram/1 milliliter and trastuzumab 60 milligram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Pertuzumab and trastuzumab only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing pertuzumab and trastuzumab in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Pertuzumab and trastuzumab only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing pertuzumab and trastuzumab (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Trastuzumab (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461181011	Trastuzumab (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481117012	Trastuzumab	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
55951000195118	trastuzumab	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
189321000077114	trastuzumab	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
71061000195118	Trastuzumab	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module