387008005: Rofecoxib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Substance with prostaglandin-endoperoxide synthase inhibitor mechanism of action (substance)\Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)\Rofecoxib (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Substance with prostaglandin-endoperoxide synthase inhibitor mechanism of action (substance)\Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)\Rofecoxib (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Analgesic (substance)\Non-opioid analgesic (substance)\Non-steroidal anti-inflammatory agent (substance)\Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)\Rofecoxib (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Sulfur and/or sulfur compound\Sulfur compound\Sulfone (substance)\Rofecoxib (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Rofecoxib (substance)	Is a	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	true	Inferred relationship	Some
Rofecoxib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Cyclooxygenase-2 inhibitor	true	Inferred relationship	Some
Rofecoxib (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Rofecoxib (substance)	Is a	Sulfone (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing rofecoxib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Rofecoxib (substance)	Inferred relationship	Some	1
Rofecoxib 12.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Some
Rofecoxib 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Some
Product containing precisely rofecoxib 2.5 milligram/1 milliliter conventional release oral suspension (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Some
Rofecoxib 5 mg/mL oral suspension	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Some
Rofecoxib 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Some
Rofecoxib-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Rofecoxib (substance)	Inferred relationship	Some	1
Rofecoxib 12.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Some	1
Rofecoxib 12.5 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Rofecoxib (substance)	Inferred relationship	Some	1
Rofecoxib 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Some	1
Rofecoxib 25 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Rofecoxib (substance)	Inferred relationship	Some	1
Rofecoxib 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Some	1
Rofecoxib 50 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Rofecoxib (substance)	Inferred relationship	Some	1
Rofecoxib 25 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Rofecoxib (substance)	Inferred relationship	Some	1
Rofecoxib 50 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Rofecoxib (substance)	Inferred relationship	Some	1
Rofecoxib 12.5 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Rofecoxib (substance)	Inferred relationship	Some	1
Product containing precisely rofecoxib 2.5 milligram/1 milliliter conventional release oral suspension (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Rofecoxib (substance)	Inferred relationship	Some	1
Product containing precisely rofecoxib 2.5 milligram/1 milliliter conventional release oral suspension (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Rofecoxib (substance)	Inferred relationship	Some	1
Rofecoxib 5 mg/mL oral suspension	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Rofecoxib (substance)	Inferred relationship	Some	1
Rofecoxib 5 mg/mL oral suspension	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Rofecoxib (substance)	Inferred relationship	Some	1
Rofecoxib only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Rofecoxib (substance)	Inferred relationship	Some	1
Product containing only rofecoxib in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Rofecoxib (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461186018	Rofecoxib (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481122012	Rofecoxib	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
371361000195117	rofecoxib	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
838651000172114	rofécoxib	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
3337461001000115	Rofecoxib	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module