387009002: Temozolomide (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with etiopathic disposition mechanism of action (substance)\Cytotoxic\Temozolomide (substance)
\Substance categorized by disposition\Immunomodulator\Alkylating agent (substance)\Triazene antineoplastic (substance)\Temozolomide (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Immunologic agent (substance)\Triazene antineoplastic (substance)\Temozolomide (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Cytotoxic\Temozolomide (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Alkylating agent (substance)\Triazene antineoplastic (substance)\Temozolomide (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Hydride (substance)\Triazene (substance)\Triazene antineoplastic (substance)\Temozolomide (substance)

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Triazene (substance)\Triazene antineoplastic (substance)\Temozolomide (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Temozolomide (substance)	Is a	Triazene antineoplastic (substance)	true	Inferred relationship	Some
Temozolomide (substance)	Is a	Cytotoxic	true	Inferred relationship	Some
Temozolomide (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Alkylating agent (disposition)	true	Inferred relationship	Some
Temozolomide (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	A substance that destroys or impairs the function of living cells	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing temozolomide (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Temozolomide (substance)	Inferred relationship	Some	1
Product containing precisely temozolomide 5 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Temozolomide (substance)	Inferred relationship	Some
Temozolomide 20 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Temozolomide (substance)	Inferred relationship	Some
Temozolomide 100 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Temozolomide (substance)	Inferred relationship	Some
Temozolomide 250 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Temozolomide (substance)	Inferred relationship	Some
Product containing precisely temozolomide 100 milligram/1 vial powder for conventional release solution for injection (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Temozolomide (substance)	Inferred relationship	Some
Product containing precisely temozolomide 180 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Temozolomide (substance)	Inferred relationship	Some
Product containing precisely temozolomide 140 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Temozolomide (substance)	Inferred relationship	Some
Product containing precisely temozolomide 5 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Temozolomide (substance)	Inferred relationship	Some	1
Product containing precisely temozolomide 5 milligram/1 each conventional release oral capsule (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Temozolomide (substance)	Inferred relationship	Some	1
Temozolomide 20 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Temozolomide (substance)	Inferred relationship	Some	1
Temozolomide 20 mg oral capsule	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Temozolomide (substance)	Inferred relationship	Some	1
Temozolomide 100 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Temozolomide (substance)	Inferred relationship	Some	1
Temozolomide 100 mg oral capsule	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Temozolomide (substance)	Inferred relationship	Some	1
Temozolomide 250 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Temozolomide (substance)	Inferred relationship	Some	1
Temozolomide 250 mg oral capsule	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Temozolomide (substance)	Inferred relationship	Some	1
Product containing precisely temozolomide 140 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Temozolomide (substance)	Inferred relationship	Some	1
Product containing precisely temozolomide 140 milligram/1 each conventional release oral capsule (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Temozolomide (substance)	Inferred relationship	Some	1
Product containing precisely temozolomide 180 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Temozolomide (substance)	Inferred relationship	Some	1
Product containing precisely temozolomide 180 milligram/1 each conventional release oral capsule (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Temozolomide (substance)	Inferred relationship	Some	1
Product containing precisely temozolomide 180 milligram/1 each conventional release oral capsule (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Temozolomide (substance)	Inferred relationship	Some	1
Temozolomide 100 mg oral capsule	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Temozolomide (substance)	Inferred relationship	Some	1
Temozolomide 250 mg oral capsule	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Temozolomide (substance)	Inferred relationship	Some	1
Product containing temozolomide in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Temozolomide (substance)	Inferred relationship	Some	1
Product containing precisely temozolomide 140 milligram/1 each conventional release oral capsule (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Temozolomide (substance)	Inferred relationship	Some	1
Product containing precisely temozolomide 5 milligram/1 each conventional release oral capsule (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Temozolomide (substance)	Inferred relationship	Some	1
Temozolomide 20 mg oral capsule	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Temozolomide (substance)	Inferred relationship	Some	1
Product containing only temozolomide (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Temozolomide (substance)	Inferred relationship	Some	1
Product containing only temozolomide in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Temozolomide (substance)	Inferred relationship	Some	1
Product containing precisely temozolomide 100 milligram/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Temozolomide (substance)	Inferred relationship	Some	1
Product containing precisely temozolomide 100 milligram/1 vial powder for conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Temozolomide (substance)	Inferred relationship	Some	1
Temozolomide-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Temozolomide (substance)	Inferred relationship	Some	1
Temozolomide only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Temozolomide (substance)	Inferred relationship	Some	1

Reference Sets

Description inactivation indicator reference set

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Id	Description	Lang	Type	Status	Case?	Module
1461187010	Temozolomide (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481123019	Temozolomide	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
59361000195119	temozolomide	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
844111000172114	témozolomide	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
74671000195116	Temozolomid	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module