387014003: Sirolimus (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Sirolimus (substance)
\Substance categorized by disposition\Antibacterial\Substance with macrolide structure and antibacterial mechanism of action (substance)\Sirolimus (substance)
\Substance categorized by disposition\Immunomodulator\Immunosuppressant (substance)\Sirolimus (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Amide\Lactam\Sirolimus (substance)

\Organic compound\Substance with ether structure\Sirolimus (substance)
\Organic compound\Organic cyclic compound\Heterocyclic compound\Lactam\Sirolimus (substance)
\Organic compound\Lactone (substance)\Macrolide (substance)\Substance with macrolide structure and antibacterial mechanism of action (substance)\Sirolimus (substance)
\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Amide\Lactam\Sirolimus (substance)
\Organic compound\Ketone\Cyclic ketone\Sirolimus (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Sirolimus (substance)	Is a	Immunosuppressant (substance)	true	Inferred relationship	Some
Sirolimus (substance)	Is a	classe d'allergènes	false	Inferred relationship	Some
Sirolimus (substance)	Is a	allergène médicamenteux	false	Inferred relationship	Some
Sirolimus (substance)	Is a	Macrolide immunosuppressant	false	Inferred relationship	Some
Sirolimus (substance)	Is a	Protein kinase inhibitor	true	Inferred relationship	Some
Sirolimus (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Protein kinase inhibitor (disposition)	true	Inferred relationship	Some
Sirolimus (substance)	Is a	Macrolide (substance)	false	Inferred relationship	Some
Sirolimus (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Sirolimus (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	A substance that modifies the immune response or the functioning of the immune system.	true	Inferred relationship	Some
Sirolimus (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Sirolimus (substance)	Is a	Cyclic ketone	true	Inferred relationship	Some
Sirolimus (substance)	Is a	Lactam	true	Inferred relationship	Some
Sirolimus (substance)	Is a	Substance with macrolide structure and antibacterial mechanism of action (substance)	true	Inferred relationship	Some
Sirolimus (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some
Sirolimus (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Antibacterial (disposition)	true	Inferred relationship	Some
Sirolimus (substance)	Is a	éther	false	Inferred relationship	Some
Sirolimus (substance)	Is a	Substance with ether structure	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing glatiramer (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Some
Product containing sirolimus (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sirolimus (substance)	Inferred relationship	Some	1
Product containing precisely sirolimus 1 milligram/1 milliliter conventional release oral solution (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Some
Sirolimus 1mg/sachet oral solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Some
Sirolimus 2mg/sachet oral solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Some
Sirolimus 1mg/mL solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Some
Sirolimus 1mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Some
Glatiramer acetate 20mg/vial injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Some
Glatiramer acetate 20 mg powder for solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Some
Glatiramer acetate 20mg/vial injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Some
Sirolimus 2 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Some
Sirolimus 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Some
Sirolimus 140mcg/cc drug eluting stent	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Some	1
Blood sirolimus measurement (procedure)	Component	False	Sirolimus (substance)	Inferred relationship	Some	2
Measurement of sirolimus (procedure)	Component	True	Sirolimus (substance)	Inferred relationship	Some	1
Sirolimus therapy (procedure)	Direct substance	True	Sirolimus (substance)	Inferred relationship	Some	2
Sirolimus 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Some	1
Sirolimus 1 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Sirolimus (substance)	Inferred relationship	Some	1
Sirolimus 2 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Some	1
Sirolimus 2 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Sirolimus (substance)	Inferred relationship	Some	1
Product containing sirolimus in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sirolimus (substance)	Inferred relationship	Some	1
Sirolimus 2 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Sirolimus (substance)	Inferred relationship	Some	1
Sirolimus 1 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Sirolimus (substance)	Inferred relationship	Some	1
Product containing precisely sirolimus 1 milligram/1 milliliter conventional release oral solution (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Sirolimus (substance)	Inferred relationship	Some	1
Product containing precisely sirolimus 1 milligram/1 milliliter conventional release oral solution (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Sirolimus (substance)	Inferred relationship	Some	1
Sirolimus only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sirolimus (substance)	Inferred relationship	Some	1
Product containing only sirolimus in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sirolimus (substance)	Inferred relationship	Some	1
Sirolimus 140 microgram/cm2 drug eluting stent (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sirolimus (substance)	Inferred relationship	Some	1
Blood sirolimus measurement (procedure)	Component	True	Sirolimus (substance)	Inferred relationship	Some	1

Reference Sets

Description inactivation indicator reference set

GB English

US English

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Id	Description	Lang	Type	Status	Case?	Module
1461192012	Sirolimus (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481128011	Sirolimus	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2672939010	Rapamycin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
59021000195112	sirolimus	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
840391000172113	sirolimus	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
74191000195112	Sirolimus	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module