387033008: Substance with protease mechanism of action (substance)

Status: retired, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 30-Jun 2022. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
proteasi	Is a	A substance containing enzymes, mainly lipase, with amylase and protease, obtained from the pancreas of the hog. It is a cream-coloured, amorphous powder having a faint characteristic, but not offensive odour. Its greatest activities are in neutral or faintly alkaline media; more than traces of mineral acids or large amounts of alkali hydroxides make it inert. An excess of alkali carbonate also inhibits its action. Pancrelipase contains, in each mg, not less than 24 USP units of lipase activity, not less than 100 USP units of amylase activity, and not less than 100 USP units of protease activity.	false	Inferred relationship	Some
proteasi	Is a	Hydrolase	false	Inferred relationship	Some
proteasi	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Protease	false	Inferred relationship	Some
proteasi	Is a	agent enzymatique	false	Inferred relationship	Some
proteasi	Is a	Substance categorized by disposition	false	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Protease-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some	1
Amylase + lipase + protease 16600unt/5000unt/18750unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 20000unt/4500unt/25000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 20000unt/5000unt/20000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 25000unt/4000unt/25000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 30000unt/10000unt/30000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 30000unt/8000unt/30000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 30000unt/8000unt/30000unt tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 3000unt/2400unt/3000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 33200unt/10000unt/37500unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 39000unt/12000unt/39000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 40000unt/8000unt/45000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 48000unt/16000unt/48000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 56000unt/20000unt/44000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 58500unt/18000unt/58500unt	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 58500unt/18000unt/58500unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 6000unt/16000unt/6000unt tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 65000unt/20000unt/65000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 66400unt/20000unt/75000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 664400unt/20000unt/75000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 70000unt/16800unt/70000unt powder	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 8000unt/30000unt/30000unt tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase + protease 12000unt/4000unt/12000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase, pancreatic + protease, pancreatic 12500unt/1000unt/12500unt tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Amylase + lipase, pancreatic + protease, pancreatic 65000unt/20000unt/65000unt capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
Product containing amylase and substance with protease mechanism of action and triacylglycerol lipase	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some	2
Product containing human protease inhibitor protein (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some
A substance containing enzymes, mainly lipase, with amylase and protease, obtained from the pancreas of the hog. It is a cream-coloured, amorphous powder having a faint characteristic, but not offensive odour. Its greatest activities are in neutral or faintly alkaline media; more than traces of mineral acids or large amounts of alkali hydroxides make it inert. An excess of alkali carbonate also inhibits its action. Pancrelipase contains, in each mg, not less than 24 USP units of lipase activity, not less than 100 USP units of amylase activity, and not less than 100 USP units of protease activity.	Is a	False	proteasi	Inferred relationship	Some
Ocriplasmin	Is a	False	proteasi	Inferred relationship	Some
Bromelains (substance)	Is a	False	proteasi	Inferred relationship	Some
Pepsin powder	Is a	False	proteasi	Inferred relationship	Some
Product containing only amylase and substance with protease mechanism of action and triacylglycerol lipase (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	proteasi	Inferred relationship	Some	2
Tissue plasminogen activator	Is a	False	proteasi	Inferred relationship	Some
Plasminogen activator	Is a	False	proteasi	Inferred relationship	Some

Reference Sets

Concept inactivation indicator reference set

SAME AS association reference set (foundation metadata concept)

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Id	Description	Lang	Type	Status	Case?	Module
1776049010	Protease	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3520807014	Substance with protease mechanism of action (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3559303012	Substance with protease mechanism of action	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
54631000195116	proteasi	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
855541000241114	protéase	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
855561000241110	substance avec mécanisme d'action protéase	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
69001000195113	Protease	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module