387220006: Phenytoin (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with cellular transport inhibitor mechanism of action (substance)\Substance with sodium channel blocker mechanism of action (substance)\Phenytoin (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Cardiovascular agent (substance)\Antiarrhythmic agent (substance)\Class I antiarrhythmic agent (substance)\Class Ib antiarrhythmic agent (substance)\Phenytoin (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Central nervous system agent (substance)\Anticonvulsant\Hydantoin derivative anticonvulsant (substance)\Phenytoin (substance)

\Diagnostic substance (substance)\Patch test substance\Extended series patch test substance\Shoe series patch test substance\Imidazolidinone\Phenytoin (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\...

\Azole\Imidazole\Hydantoin and/or hydantoin derivative (substance)\Hydantoin derivative (substance)\Hydantoin derivative anticonvulsant (substance)\Phenytoin (substance)

\Amide and/or amide derivative (substance)\Imidazolidinone\Phenytoin (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound\Azole\Imidazole\Hydantoin and/or hydantoin derivative (substance)\Hydantoin derivative (substance)\Hydantoin derivative anticonvulsant (substance)\Phenytoin (substance)
\Organic compound\Organic nitrogen compound\Azole\Imidazole\Hydantoin and/or hydantoin derivative (substance)\Hydantoin derivative (substance)\Hydantoin derivative anticonvulsant (substance)\Phenytoin (substance)
\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Imidazolidinone\Phenytoin (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Phenytoin (substance)	Is a	Hydantoin (substance)	false	Inferred relationship	Some
Phenytoin (substance)	Is a	Class Ib antiarrhythmic agent (substance)	true	Inferred relationship	Some
Phenytoin (substance)	Is a	Hydantoin derivative anticonvulsant (substance)	true	Inferred relationship	Some
Phenytoin (substance)	Is a	Imidazolidinone	true	Inferred relationship	Some
Phenytoin (substance)	Is a	Substance with sodium channel blocker mechanism of action (substance)	true	Inferred relationship	Some
Phenytoin (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Sodium channel blocker	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Phenytoin, free measurement	Component	False	Phenytoin (substance)	Inferred relationship	Some
Gingival hypertrophy caused by diphenylhydantoin (disorder)	Causative agent (attribute)	False	Phenytoin (substance)	Inferred relationship	Some	2
Accidental overdose of phenytoin	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Some	1
Phenytoin blood measurement	Component	False	Phenytoin (substance)	Inferred relationship	Some	2
Serum phenytoin measurement	Component	False	Phenytoin (substance)	Inferred relationship	Some	2
Accidental phenytoin poisoning (disorder)	Causative agent (attribute)	False	Phenytoin (substance)	Inferred relationship	Some
Intentional phenytoin poisoning	Causative agent (attribute)	False	Phenytoin (substance)	Inferred relationship	Some
intoxication par la phénytoïne d'intention indéterminée	Causative agent (attribute)	False	Phenytoin (substance)	Inferred relationship	Some	1
Phenytoin adverse reaction	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Some	1
Allergy to phenytoin (finding)	Causative agent (attribute)	False	Phenytoin (substance)	Inferred relationship	Some
Phenytoin overdose	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Some	1
Intentional phenytoin overdose	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Some	1
surdose de phénytoïne d'intention indéterminée	Causative agent (attribute)	False	Phenytoin (substance)	Inferred relationship	Some	1
Phenytoin 6 mg/mL oral suspension	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Phenytoin (substance)	Inferred relationship	Some
Phenytoin 90mg/5mL s/f suspension	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Phenytoin (substance)	Inferred relationship	Some
Phenytoin measurement	Component	True	Phenytoin (substance)	Inferred relationship	Some	1
Product containing precisely phenytoin 25 milligram/1 milliliter conventional release oral suspension (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Phenytoin (substance)	Inferred relationship	Some
Pentobarbital sodium 390mg/phenytoin sodium 50mg injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Phenytoin (substance)	Inferred relationship	Some
Phenytoin sodium (substance)	Is a	False	Phenytoin (substance)	Inferred relationship	Some
Product containing phenytoin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Phenytoin (substance)	Inferred relationship	Some	1
Product containing phenytoin in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Phenytoin (substance)	Inferred relationship	Some	1
Product containing phenytoin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Phenytoin (substance)	Inferred relationship	Some	1
Drug-induced lupus erythematosus caused by diphenylhydantoin	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Some	1
Poisoning by phenytoin	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Some	1
Accidental phenytoin poisoning (disorder)	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Some	1
Intentional phenytoin poisoning	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Some	1
Purple glove syndrome	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Some	1
Product containing precisely phenytoin 50 milligram/1 each conventional release chewable tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Phenytoin (substance)	Inferred relationship	Some
Allergy to phenytoin (finding)	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Some	1
Free phenytoin (substance)	Is a	False	Phenytoin (substance)	Inferred relationship	Some
Free phenytoin (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	False	Phenytoin (substance)	Inferred relationship	Some
Phenytoin sodium (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Phenytoin (substance)	Inferred relationship	Some
Product containing precisely phenytoin 50 milligram/1 each conventional release chewable tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Phenytoin (substance)	Inferred relationship	Some	1
Product containing precisely phenytoin 50 milligram/1 each conventional release chewable tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Phenytoin (substance)	Inferred relationship	Some	1
Phenytoin 18 mg/mL oral suspension	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Phenytoin (substance)	Inferred relationship	Some	1
Phenytoin 18 mg/mL oral suspension	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Phenytoin (substance)	Inferred relationship	Some	1
Phenytoin 6 mg/mL oral suspension	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Phenytoin (substance)	Inferred relationship	Some	1
Phenytoin 6 mg/mL oral suspension	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Phenytoin (substance)	Inferred relationship	Some	1
Phenytoin only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Phenytoin (substance)	Inferred relationship	Some	1
Phenytoin only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Phenytoin (substance)	Inferred relationship	Some	1
Phenytoin only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Phenytoin (substance)	Inferred relationship	Some	1
Product containing precisely phenytoin 25 milligram/1 milliliter conventional release oral suspension (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Phenytoin (substance)	Inferred relationship	Some	1
Product containing precisely phenytoin 25 milligram/1 milliliter conventional release oral suspension (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Phenytoin (substance)	Inferred relationship	Some	1
Gingival hypertrophy caused by diphenylhydantoin (disorder)	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Some	1
EMPACT (erythema multiforme associated with phenytoin and cranial radiation therapy) syndrome	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Some	1
Phenytoin calcium	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Phenytoin (substance)	Inferred relationship	Some
Serum phenytoin measurement	Component	True	Phenytoin (substance)	Inferred relationship	Some	1
Phenytoin blood measurement	Component	True	Phenytoin (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461398018	Phenytoin (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481323014	Phenytoin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1491929016	Diphenylhydantoin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1491930014	DPH	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
54681000195117	fenitoina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
861951000172115	phénytoïne	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
69061000195112	Phenytoin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module