387297002: Melphalan (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with etiopathic disposition mechanism of action (substance)\Carcinogen\Melphalan (substance)
\Substance categorized by disposition\Immunomodulator\Immunosuppressant (substance)\Melphalan (substance)
\Substance categorized by disposition\Immunomodulator\Alkylating agent (substance)\Nitrogen mustard derivative (substance)\Melphalan (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Immunologic agent (substance)\Nitrogen mustard derivative (substance)\Melphalan (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Immunosuppressant (substance)\Melphalan (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Alkylating agent (substance)\Nitrogen mustard derivative (substance)\Melphalan (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Melphalan (substance)	Is a	Nitrogen mustard derivative (substance)	true	Inferred relationship	Some
Melphalan (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Alkylating agent (disposition)	true	Inferred relationship	Some
Melphalan (substance)	Is a	Immunosuppressant (substance)	true	Inferred relationship	Some
Melphalan (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	A substance that increases the risk of neoplasms in humans or animals either by directly affecting DNA or inducing neoplasms by other mechanisms	true	Inferred relationship	Some
Melphalan (substance)	Is a	Carcinogen	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Melphalan poisoning	Causative agent (attribute)	True	Melphalan (substance)	Inferred relationship	Some	1
Accidental melphalan poisoning	Causative agent (attribute)	False	Melphalan (substance)	Inferred relationship	Some
Intentional melphalan poisoning	Causative agent (attribute)	False	Melphalan (substance)	Inferred relationship	Some
intoxication par le melphalan d'intention indéterminée	Causative agent (attribute)	False	Melphalan (substance)	Inferred relationship	Some	1
Melphalan adverse reaction	Causative agent (attribute)	True	Melphalan (substance)	Inferred relationship	Some	1
Allergy to melphalan (finding)	Causative agent (attribute)	False	Melphalan (substance)	Inferred relationship	Some
Melphalan overdose	Causative agent (attribute)	True	Melphalan (substance)	Inferred relationship	Some	1
Accidental melphalan overdose	Causative agent (attribute)	True	Melphalan (substance)	Inferred relationship	Some	1
Intentional melphalan overdose	Causative agent (attribute)	True	Melphalan (substance)	Inferred relationship	Some	1
surdose de melphalan d'intention indéterminée	Causative agent (attribute)	False	Melphalan (substance)	Inferred relationship	Some	1
Melphalan 50mg powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Melphalan (substance)	Inferred relationship	Some
Melphalan 2 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Melphalan (substance)	Inferred relationship	Some
Melphalan 50mg/vial injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Melphalan (substance)	Inferred relationship	Some
Product containing melphalan (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Melphalan (substance)	Inferred relationship	Some	1
Melphalan 50mg/vial powder for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Melphalan (substance)	Inferred relationship	Some
Accidental melphalan poisoning	Causative agent (attribute)	True	Melphalan (substance)	Inferred relationship	Some	1
Intentional melphalan poisoning	Causative agent (attribute)	True	Melphalan (substance)	Inferred relationship	Some	1
Melphalan hydrochloride (substance)	Is a	False	Melphalan (substance)	Inferred relationship	Some
Allergy to melphalan (finding)	Causative agent (attribute)	True	Melphalan (substance)	Inferred relationship	Some	1
Melphalan 2 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Melphalan (substance)	Inferred relationship	Some	1
Melphalan 2 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Melphalan (substance)	Inferred relationship	Some	1
Melphalan hydrochloride (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Melphalan (substance)	Inferred relationship	Some
Melphalan 2 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Melphalan (substance)	Inferred relationship	Some	1
Product containing precisely melphalan (as melphalan hydrochloride) 50 milligram/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Melphalan (substance)	Inferred relationship	Some	1
Product containing melphalan in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Melphalan (substance)	Inferred relationship	Some	1
Melphalan-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Melphalan (substance)	Inferred relationship	Some	1
Melphalan only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Melphalan (substance)	Inferred relationship	Some	1
Melphalan only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Melphalan (substance)	Inferred relationship	Some	1
Melphalan only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Melphalan (substance)	Inferred relationship	Some	1
Melphalan flufenamide (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Melphalan (substance)	Inferred relationship	Some
Product containing precisely melphalan (as melphalan hydrochloride) 50 milligram/1 vial powder for conventional release solution for infusion and/or injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Melphalan (substance)	Inferred relationship	Some	1
Melphalan (as melphalan hydrochloride) 50 mg powder for solution for infusion vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Melphalan (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461475013	Melphalan (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481398013	Melphalan	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1491978014	Phenylalanine mustard	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1491979018	L-sarcolysin	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
58711000195110	melphalan	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
8001000188114	mélphalan	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
823461000172119	melphalan	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
73871000195117	Melphalan	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module