387332007: Isosorbide dinitrate (substance)

SNOMED CT Concept\Substance\...

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Cardiovascular agent (substance)\Hypotensive agent (substance)\Vasodilator (substance)\Nitrate-based vasodilating agent (substance)\Isosorbide dinitrate (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\...

\Nitrate-based vasodilating agent (substance)\Isosorbide dinitrate (substance)

\Nitrous acid ester\Isosorbide dinitrate (substance)

\Organic compound\Organic cyclic compound\Isosorbide dinitrate (substance)
\Organic compound\Ester\Nitrous acid ester\Isosorbide dinitrate (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Isosorbide dinitrate (substance)	Is a	Isosorbide (substance)	false	Inferred relationship	Some
Isosorbide dinitrate (substance)	Is a	Nitrate-based vasodilating agent (substance)	true	Inferred relationship	Some
Isosorbide dinitrate (substance)	Is a	Nitrous acid ester	true	Inferred relationship	Some
Isosorbide dinitrate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	Isosorbide (substance)	false	Inferred relationship	Some
Isosorbide dinitrate (substance)	Is a	Organic cyclic compound	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Isosorbide dinitrate adverse reaction	Causative agent (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Parenteral isosorbide dinitrate adverse reaction	Causative agent (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Oral isosorbide dinitrate adverse reaction	Causative agent (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Modified release isosorbide dinitrate adverse reaction	Causative agent (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
allergie au dinitrate d'isosorbide	Causative agent (attribute)	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Parenteral isosorbide dinitrate allergy	Causative agent (attribute)	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Oral isosorbide dinitrate allergy	Causative agent (attribute)	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Modified release isosorbide dinitrate allergy	Causative agent (attribute)	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate overdose (disorder)	Causative agent (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate [generic additions]	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 5mg sublingual tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 20 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 30 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 20mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
dinitrate d'isosorbide 500 microgrammes/mL, fiole de 50 mL de solution pour injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 1.25 mg/actuation sublingual spray	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 30mg transdermal spray	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 40mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
dinitrate d'isosorbide 1 mg/mL, ampoule de 10 mL de solution pour injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
dinitrate d'isosorbide 1 mg/mL, fiole de 50 mL de solution pour injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Modified release isosorbide dinitrate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing isosorbide dinitrate in parenteral dosage form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing isosorbide dinitrate in oral dosage form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Transdermal isosorbide dinitrate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing precisely isosorbide dinitrate 2.5 milligram/1 each conventional release sublingual tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 40 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 40mg m/r capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing isosorbide dinitrate (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing hydralazine and isosorbide dinitrate (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing precisely hydralazine 37.5 milligram and isosorbide dinitrate 20 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing precisely isosorbide dinitrate 10 milligram/1 each conventional release sublingual tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing isosorbide dinitrate in sublingual dosage form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 5 mg sublingual tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing isosorbide dinitrate in oropharyngeal dosage form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Oral isosorbide dinitrate allergy	Causative agent (attribute)	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
allergie au dinitrate d'isosorbide	Causative agent (attribute)	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Modified release isosorbide dinitrate allergy	Causative agent (attribute)	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Parenteral isosorbide dinitrate allergy	Causative agent (attribute)	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 10 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 20 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 20 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 30 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 30 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 5 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 40 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 40 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely hydralazine 37.5 milligram and isosorbide dinitrate 20 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Product containing precisely hydralazine 37.5 milligram and isosorbide dinitrate 20 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Product containing precisely hydralazine 37.5 milligram and isosorbide dinitrate 20 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 20 milligram/1 each prolonged-release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 20 milligram/1 each prolonged-release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 40 milligram/1 each prolonged-release oral capsule (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 40 milligram/1 each prolonged-release oral capsule (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 40 milligram/1 each prolonged-release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 40 milligram/1 each prolonged-release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 30 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 10 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 20 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely hydralazine 37.5 milligram and isosorbide dinitrate 20 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 5 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 40 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 1.25 mg/actuation sublingual spray	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 1.25 mg/actuation sublingual spray	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 30 mg/actuation transdermal spray	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 30 mg/actuation transdermal spray	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 10 milligram/10 milliliter conventional release solution for injection ampule	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 10 milligram/10 milliliter conventional release solution for injection ampule	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 50 milligram/50 milliliter conventional release solution for injection bottle	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 50 milligram/50 milliliter conventional release solution for injection bottle	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 25 milligram/50 milliliter conventional release solution for injection bottle	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 25 milligram/50 milliliter conventional release solution for injection bottle	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 500 microgram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 500 microgram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 1 mg/mL solution for injection	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 1 mg/mL solution for injection	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 10 milligram/1 each conventional release sublingual tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 10 milligram/1 each conventional release sublingual tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 5 mg sublingual tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 5 mg sublingual tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 2.5 milligram/1 each conventional release sublingual tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 2.5 milligram/1 each conventional release sublingual tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Hydralazine hydrochloride 37.5 mg and isosorbide dinitrate 20 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Hydralazine hydrochloride 37.5 mg and isosorbide dinitrate 20 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Product containing only isosorbide dinitrate (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing isosorbide dinitrate (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing hydralazine and isosorbide dinitrate (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Product containing only hydralazine and isosorbide dinitrate (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Hydralazine- and isosorbide dinitrate-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Product containing only hydralazine and isosorbide dinitrate in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Isosorbide dinitrate only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate-containing product in oromucosal dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate only product in oromucosal dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate-containing product in transdermal dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate only product in transdermal dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461510013	Isosorbide dinitrate (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481431017	Isosorbide dinitrate	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
57531000195110	isosorbide dinitrato	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
15271000188119	isosorbide dinitrate	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
819101000172116	dinitrate d'isosorbide	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
72711000195114	Isosorbid dinitrat	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
236701000195116	Isosorbiddinitrat	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module