387420009: Cyclophosphamide (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Immunomodulator\Alkylating agent (substance)\Nitrogen mustard derivative (substance)\Cyclophosphamide (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Immunologic agent (substance)\Nitrogen mustard derivative (substance)\Cyclophosphamide (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Alkylating agent (substance)\Nitrogen mustard derivative (substance)\Cyclophosphamide (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Cyclophosphamide (substance)	Is a	Nitrogen mustard derivative (substance)	true	Inferred relationship	Some
Cyclophosphamide (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Alkylating agent (disposition)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Accidental cyclophosphamide poisoning	Causative agent (attribute)	False	Cyclophosphamide (substance)	Inferred relationship	Some
Intentional cyclophosphamide poisoning	Causative agent (attribute)	False	Cyclophosphamide (substance)	Inferred relationship	Some
intoxication par le cyclophosphamide d'intention indéterminée	Causative agent (attribute)	False	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide adverse reaction	Causative agent (attribute)	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Allergy to cyclophosphamide (finding)	Causative agent (attribute)	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide overdose	Causative agent (attribute)	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Accidental cyclophosphamide overdose	Causative agent (attribute)	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Intentional cyclophosphamide overdose	Causative agent (attribute)	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
surdose de cyclophosphamide d'intention indéterminée	Causative agent (attribute)	False	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Product containing precisely cyclophosphamide (as cyclophosphamide monohydrate) 200 milligram/1 vial powder for conventional release solution for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 20mg/mL infusion solution 200mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 20mg/mL infusion solution 100mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 20mg/mL infusion solution 50mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 100mg/vial injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 200mg/vial injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 500mg/vial injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 1g/vial injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 2g/vial injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 100mg/vial powder for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 1000mg/vial injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Product containing cyclophosphamide in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Poisoning by cyclophosphamide	Causative agent (attribute)	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Product containing cyclophosphamide (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide 200mg/vial powder for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 1g/vial powder for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 500mg/vial powder for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Product containing precisely cyclophosphamide (as cyclophosphamide monohydrate) 2 gram/1 vial powder for conventional release solution for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Product containing precisely cyclophosphamide (as cyclophosphamide monohydrate) 500 milligram/1 vial powder for conventional release solution for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Product containing precisely cyclophosphamide (as cyclophosphamide monohydrate) 1 gram/1 vial powder for conventional release solution for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some
Accidental cyclophosphamide poisoning	Causative agent (attribute)	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Intentional cyclophosphamide poisoning	Causative agent (attribute)	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Allergy to cyclophosphamide (finding)	Causative agent (attribute)	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide therapy (procedure)	Direct substance	True	Cyclophosphamide (substance)	Inferred relationship	Some	2
Rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone chemotherapy regimen (regime/therapy)	Direct substance	True	Cyclophosphamide (substance)	Inferred relationship	Some	8
Cyclophosphamide monohydrate (substance)	Is a	False	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide 50 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide 25 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide monohydrate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Cyclophosphamide (substance)	Inferred relationship	Some
Cyclophosphamide 25 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide 50 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Product containing precisely cyclophosphamide (as cyclophosphamide monohydrate) 2 gram/1 vial powder for conventional release solution for injection	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Cyclophosphamide (substance)	Inferred relationship	Some	1
Product containing precisely cyclophosphamide (as cyclophosphamide monohydrate) 1 gram/1 vial powder for conventional release solution for injection	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Cyclophosphamide (substance)	Inferred relationship	Some	1
Product containing precisely cyclophosphamide (as cyclophosphamide monohydrate) 200 milligram/1 vial powder for conventional release solution for injection	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Cyclophosphamide (substance)	Inferred relationship	Some	1
Product containing precisely cyclophosphamide (as cyclophosphamide monohydrate) 500 milligram/1 vial powder for conventional release solution for injection	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Cyclophosphamide (substance)	Inferred relationship	Some	1
Product containing only cyclophosphamide (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Product containing only cyclophosphamide in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
R-CEOP (rituximab, cyclophosphamide, etoposide, vincristine, prednisone) antineoplastic chemotherapy	Direct substance	True	Cyclophosphamide (substance)	Inferred relationship	Some	5
Product containing precisely cyclophosphamide 2 gram/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Product containing precisely cyclophosphamide 2 gram/1 vial powder for conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide 200 mg powder for solution for injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide 200 mg powder for solution for injection vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide 500 mg powder for solution for injection vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide 500 mg powder for solution for injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide 1 g powder for solution for injection vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide 1 g powder for solution for injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Cyclophosphamide (substance)	Inferred relationship	Some	1
Cyclophosphamide anhydrous (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Cyclophosphamide (substance)	Inferred relationship	Some

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461598019	Cyclophosphamide (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481512014	Cyclophosphamide	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1492061017	CPM	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
1492062012	CTX	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
1492063019	CYT	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
59751000195118	ciclofosfamide	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
803221000172116	cyclophosphamide	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
75111000195117	Cyclophosphamid	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module