387568001: Clozapine (substance)

SNOMED CT Concept\Substance\...

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Central nervous system agent (substance)\Psychoactive substance (substance)\Psychotropic agent (substance)\Anti-psychotic agent (substance)\Clozapine (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Heterocyclic compound\Piperazine and/or piperazine derivative (substance)\Piperazine derivative\Clozapine (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Clozapine (substance)	Is a	Atypical antipsychotic	false	Inferred relationship	Some
Clozapine (substance)	Is a	classe d'allergènes	false	Inferred relationship	Some
Clozapine (substance)	Is a	allergène médicamenteux	false	Inferred relationship	Some
Clozapine (substance)	Is a	pipérazine	false	Inferred relationship	Some
Clozapine (substance)	Is a	Piperazine derivative	true	Inferred relationship	Some
Clozapine (substance)	Is a	Anti-psychotic agent (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Clozapine measurement	Component	True	Clozapine (substance)	Inferred relationship	Some	1
Clozapine poisoning	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Some	1
Accidental clozapine poisoning	Causative agent (attribute)	False	Clozapine (substance)	Inferred relationship	Some
Intentional clozapine poisoning	Causative agent (attribute)	False	Clozapine (substance)	Inferred relationship	Some
intoxication par la clozapine d'intention indéterminée	Causative agent (attribute)	False	Clozapine (substance)	Inferred relationship	Some	1
Clozapine adverse reaction	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Some	1
Allergy to clozapine	Causative agent (attribute)	False	Clozapine (substance)	Inferred relationship	Some
Clozapine overdose	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Some	1
Accidental clozapine overdose (disorder)	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Some	1
Intentional clozapine overdose	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Some	1
surdose de clozapine d'intention indéterminée	Causative agent (attribute)	False	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some
Clozapine 100 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some
Product containing clozapine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clozapine (substance)	Inferred relationship	Some	1
Product containing only clozapine orally disintegrating 25 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some
Product containing only clozapine orally disintegrating 100 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some
Clozapine 12.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some
Accidental clozapine poisoning	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Some	1
Intentional clozapine poisoning	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some
Product containing only clozapine orally disintegrating 12.5 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some
Product containing only clozapine orally disintegrating 50 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some
Allergy to clozapine	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Some	1
Clozapine-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clozapine (substance)	Inferred relationship	Some	1
Clozapine therapy (procedure)	Direct substance	True	Clozapine (substance)	Inferred relationship	Some	2
Clozapine 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 25 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 100 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 100 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clozapine (substance)	Inferred relationship	Some	1
Product containing only clozapine orally disintegrating 25 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some	1
Product containing only clozapine orally disintegrating 25 mg/1 each oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clozapine (substance)	Inferred relationship	Some	1
Product containing only clozapine orally disintegrating 100 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some	1
Product containing only clozapine orally disintegrating 100 mg/1 each oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 12.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 12.5 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 50 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clozapine (substance)	Inferred relationship	Some	1
Product containing only clozapine orally disintegrating 12.5 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some	1
Product containing only clozapine orally disintegrating 12.5 mg/1 each oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clozapine (substance)	Inferred relationship	Some	1
Product containing only clozapine orally disintegrating 50 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Some	1
Product containing only clozapine orally disintegrating 50 mg/1 each oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 100 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 50 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 12.5 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 25 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Clozapine (substance)	Inferred relationship	Some	1
Product containing only clozapine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clozapine (substance)	Inferred relationship	Some	1
Clozapine only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clozapine (substance)	Inferred relationship	Some	1
Monitoring of clozapine therapy	Direct substance	True	Clozapine (substance)	Inferred relationship	Some	2
Product containing precisely clozapine 200 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clozapine (substance)	Inferred relationship	Some	1
Product containing precisely clozapine 200 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 50 mg/mL oral suspension	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Clozapine (substance)	Inferred relationship	Some	1
Clozapine 50 mg/mL oral suspension	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clozapine (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461746018	Clozapine (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481658018	Clozapine	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
54791000195114	clozapina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
802221000172111	clozapine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
69171000195119	Clozapin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module